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1. Abbasi-Kesbi R, Memarzadeh-Tehran H, Deen MJ: Technique to estimate human reaction time based on visual perception. Healthc Technol Lett; 2017 Apr;4(2):73-77

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Technique to estimate human reaction time based on visual perception.
  • The design and implementation of a wearable system to estimate the human reaction time (HRT) to visual stimulus based on two identical wireless motion sensors are described.
  • Relevant tests to estimate the HRT are performed in two different scenarios including <i>simple</i> and <i>recognition</i> tests for 90 pairs of measurements.
  • The root mean square error, standard deviation error and mean error of the results are 2.88, 6.17 and 0.3 ms for <i>simple</i> test while for <i>recognition</i> test as low as 3.34, 7.83 and 0.35 ms, respectively.
  • The outcomes of the HRT estimation tests confirm HRT can increase by 40-87% due to increased fatigue levels.

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  • [Cites] Sports Med. 1998 Oct;26(4):217-38 [9820922.001]
  • [Cites] Healthc Technol Lett. 2015 Jul 13;2(4):95-100 [26609413.001]
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  • (PMID = 28461901.001).
  • [ISSN] 2053-3713
  • [Journal-full-title] Healthcare technology letters
  • [ISO-abbreviation] Healthc Technol Lett
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; HRT / biomechanics / fatigue / fatigue levels / frequency 2.45 GHz / gyroscope / gyroscopes / human reaction time / mean error / mean square error methods / recognition test / root mean square error / simple test / standard deviation error / telemedicine / time 0.35 ms / time 3.34 ms / time 7.83 ms / transceiver / transceivers / visual perception / visual stimulus / wearable system / wireless motion sensors / wireless sensor networks
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2. Szeto DP, Griffin KJ, Kimelman D: HrT is required for cardiovascular development in zebrafish. Development; 2002 Nov;129(21):5093-101
ZFIN. ZFIN .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] HrT is required for cardiovascular development in zebrafish.
  • The recently identified zebrafish T-box gene hrT is expressed in the developing heart and in the endothelial cells forming the dorsal aorta.
  • Orthologs of hrT are expressed in cardiovascular cells from Drosophila to mouse, suggesting that the function of hrT is evolutionarily conserved.
  • The role of hrT in cardiovascular development, however, has not thus far been determined in any animal model.
  • Using morpholino antisense oligonucleotides, we show that zebrafish embryos lacking hrT function have dysmorphic hearts and an absence of blood circulation.
  • Although the early events in heart formation were normal in hrT morphant embryos, subsequently the hearts failed to undergo looping, and late onset defects in chamber morphology and gene expression were observed.
  • In particular, we found that the loss of hrT function led to a dramatic upregulation of tbx5, a gene required for normal heart morphogenesis.
  • Conversely, we show that overexpression of hrT causes a significant downregulation of tbx5, indicating that one key role of hrT is to regulate the levels of tbx5.
  • Secondly, we found that HrT is required to inhibit the expression of the blood lineage markers gata1 and gata2 in the most posterior lateral plate mesoderm.
  • Finally, we show that HrT is required for vasculogenesis in the trunk, leading to similar vascular defects to those observed in midline mutants such as floating head. hrT expression in the vascular progenitors depends upon midline mesoderm, indicating that this expression is one important component of the response to a midline-derived signal during vascular morphogenesis.
  • [MeSH-minor] Animals. Gene Expression Regulation, Developmental. Heart Defects, Congenital / embryology. Heart Defects, Congenital / genetics. Hematopoiesis / genetics. Hematopoiesis / physiology. Homeodomain Proteins / genetics. Homeodomain Proteins / physiology. Humans. In Situ Hybridization. Mice. Mutation. Oligodeoxyribonucleotides, Antisense / genetics. Oligodeoxyribonucleotides, Antisense / pharmacology. Recombinant Fusion Proteins / genetics. Transcription Factors / genetics. Transcription Factors / physiology

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  • (PMID = 12397116.001).
  • [ISSN] 0950-1991
  • [Journal-full-title] Development (Cambridge, England)
  • [ISO-abbreviation] Development
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / F32 HD08725; United States / PHS HHS / / T32 07312
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Homeodomain Proteins; 0 / Oligodeoxyribonucleotides, Antisense; 0 / Recombinant Fusion Proteins; 0 / T-Box Domain Proteins; 0 / T-box transcription factor 5; 0 / TBX20 protein, human; 0 / Tbx20 protein, mouse; 0 / Transcription Factors; 0 / Zebrafish Proteins; 0 / flh protein, zebrafish; 0 / tbx20 protein, zebrafish
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3. Tagliabue M, Gianfranchi E, Sarlo M: A First Step toward the Understanding of Implicit Learning of Hazard Anticipation in Inexperienced Road Users Through a Moped-Riding Simulator. Front Psychol; 2017;8:768

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In the present study, we attempted to understand how the ability to anticipate hazards develops during training with a moped-riding simulator: the Honda Riding Trainer (HRT).
  • Several studies have already validated the HRT as a tool to enhance adolescents' hazard perception and riding abilities.
  • We administered to a group of inexperienced road users five road courses two times a week apart.
  • Participants had to ride along the HRT courses, facing the potentially hazardous situations, following traffic rules, and trying to avoid accidents.

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  • (PMID = 28553254.001).
  • [ISSN] 1664-1078
  • [Journal-full-title] Frontiers in psychology
  • [ISO-abbreviation] Front Psychol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; electrodermal activity / hazard perception / learning processes / moped-riding abilities / novice road users
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4. Brufani M, Rizzi N, Meda C, Filocamo L, Ceccacci F, D'Aiuto V, Bartoli G, Bella A, Migneco LM, Bettolo RM, Leonelli F, Ciana P, Maggi A: Novel Locally Active Estrogens Accelerate Cutaneous Wound Healing-Part 2. Sci Rep; 2017 May 31;7(1):2510

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Estrogen deprivation is associated with delayed healing, while estrogen replacement therapy (ERT) accelerates acute wound healing and protects against development of chronic wounds.

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  • (PMID = 28566747.001).
  • [ISSN] 2045-2322
  • [Journal-full-title] Scientific reports
  • [ISO-abbreviation] Sci Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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5. Meuret AE, Simon E, Bhaskara L, Ritz T: Ultra-brief behavioral skills trainings for blood injection injury phobia. Depress Anxiety; 2017 Mar 15;
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • One of the interventions was a novel Hypoventilation Respiratory Training (HRT) aimed at reducing the exaggerated ventilation response (hyperventilation) seen in BII phobia.
  • METHOD: Sixty BII patients were randomly assigned to one of three 12-min video-guided trainings: Symptom-Associated Tension (SAT) training, Relaxation Skills Training (RST), or HRT.
  • RESULTS: Both SAT and HRT resulted in overall greater reductions of phobic fears and symptoms than RST.
  • SAT significantly increased heart rate during exposure, and HRT led to significantly reduced ventilation, increases in PCO<sub>2</sub> , and elevated blood pressure throughout exposure and recovery.
  • Treatment expectancy was rated equally high across conditions, whereas credibility ratings were highest for HRT.
  • CONCLUSIONS: Brief, video-based instructions in muscle tension and normocapnic breathing are effective in reducing BII symptom severity and require minimal time and expertise.
  • HRT may be particularly helpful in reducing fainting caused by cerebral vasoconstriction.

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  • [Copyright] © 2017 Wiley Periodicals, Inc.
  • (PMID = 28294471.001).
  • [ISSN] 1520-6394
  • [Journal-full-title] Depression and anxiety
  • [ISO-abbreviation] Depress Anxiety
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; applied tension / biological markers / blood injection injury phobia / blood phobia / brief intervention / exposure / hyperventilation
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6. Compston JE: The risks and benefits of HRT. J Musculoskelet Neuronal Interact; 2004 Jun;4(2):187-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The risks and benefits of HRT.
  • For many years hormone replacement therapy (HRT) was regarded as the gold standard for treatment of osteoporosis.
  • The current consensus is that HRT is no longer regarded as a front-line option for prevention of osteoporotic fractures and that its use for this purpose should be restricted to women with osteoporosis who have menopausal symptoms and to older women who are intolerant of other therapies and/or express a strong preference for HRT despite being informed about potential adverse effects.
  • Nevertheless, the mechanisms by which estrogen exerts its beneficial skeletal effects remain a major area of research that has important implications for the development of novel therapies.
  • [MeSH-major] Breast Neoplasms / epidemiology. Cardiovascular Diseases / epidemiology. Estrogen Replacement Therapy / adverse effects. Osteoporosis / drug therapy

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  • (PMID = 15615123.001).
  • [ISSN] 1108-7161
  • [Journal-full-title] Journal of musculoskeletal & neuronal interactions
  • [ISO-abbreviation] J Musculoskelet Neuronal Interact
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Number-of-references] 25
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7. Maslin JS, Mansouri K, Dorairaj SK: HRT for the Diagnosis and Detection of Glaucoma Progression. Open Ophthalmol J; 2015;9:58-67

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] HRT for the Diagnosis and Detection of Glaucoma Progression.
  • Confocal scanning laser ophthalmoscopy through the Heidelberg Retina Tomograph (HRT) provides a rapid, safe, noncontact, and noninvasive imaging of the optic disc in three-dimensions, and provides precise detailed information about the optic disc beyond that which the clinical exam can measure.
  • The HRT I was developed for research purposes only and was not used clinically.
  • The HRT II was developed to be user-friendly, more rapid, and was used as an adjunct to clinical examination in the detection and progression of glaucoma.
  • One of the main pitfalls of the HRT II was that it was operator-dependent.
  • The HRT III was developed to be operator-independent.
  • Numerous studies have compared these two methods of analysis, with the conclusion that the Glaucoma Probability Score provides a higher sensitivity and a lower specificity than the Moorsfield Regression Analysis, which may indicate that it has potential as a screening test for glaucoma.
  • However, there is no consensus on the use of the Glaucoma Probability Score as a screening test for glaucoma.
  • While HRT data may be useful as a clinical adjunct in the screening and diagnosis of glaucoma, it should ultimately only be used to support clinical examination.

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  • (PMID = 26069518.001).
  • [ISSN] 1874-3641
  • [Journal-full-title] The open ophthalmology journal
  • [ISO-abbreviation] Open Ophthalmol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4460217
  • [Keywords] NOTNLM ; Glaucoma / Heidelberg retina tomograph / retinal nerve fiber layer / topographic change analysis
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8. Cerrillo M, Herrero L, Guillén A, Mayoral M, García-Velasco JA: Impact of Endometrial Preparation Protocols for Frozen Embryo Transfer on Live Birth Rates. Rambam Maimonides Med J; 2017 Apr 28;8(2)

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: It has been reported that a natural cycle (NC) is similar to or even better than hormone replacement therapy (HRT) in patients with regular cycles who undergo frozen embryo transfer (FET).
  • METHODS: Hence we carried out a prospective study between June 2011 and June 2012, which included 530 patients (570 FET cycles) randomly allocated to two study groups: Group 1 (n=280 cycles), artificial cycle (HRT); or group 2 (n=290 cycles), natural cycle.
  • Natural cycles were later divided into two groups: 169 patients scheduled with human chorionic gonadotropin (hCG) and 121 with endogenous luteinizing hormone (LH) surge.
  • The exclusion criteria were polycystic ovarian syndrome and endometriosis stage III/IV.
  • RESULTS: No statistical differences were found in the baseline characteristics among groups, nor between implantation or ongoing pregnancy rates (30.8% HRT group; 32.7% hCG group; 34.5% LH surge group).
  • However, a higher miscarriage rate was observed in the HRT group when compared to hCG or LH surge (21.2% versus 12.9% versus 11.1%, P<0.01).
  • CONCLUSIONS: We conclude that scheduling FET with HRT on weekdays and avoiding work overload at weekends prove efficient and safe in cycle outcome terms.
  • Another reason for the convenience of an HRT protocol is having fewer visits to the clinic compared to natural cycle protocols.

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  • (PMID = 28467767.001).
  • [ISSN] 2076-9172
  • [Journal-full-title] Rambam Maimonides medical journal
  • [ISO-abbreviation] Rambam Maimonides Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Israel
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9. Sismondi P, Biglia N, Giai M, Ponzone R, Roagna R, Sgro L, Campagnoli C: HRT, breast and endometrial cancers: strategies and intervention options. Maturitas; 1999 Aug 16;32(3):131-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] HRT, breast and endometrial cancers: strategies and intervention options.
  • The demand for hormone replacement therapy (HRT) by women who enter the menopause is rapidly increasing in all developed countries.
  • The concern that HRT may enhance morbidity and mortality from malignant diseases still limits the widespread adoption of hormonal treatments.
  • Overall, epidemiological data on cancer incidence and HRT are reassuring, although long-term or inappropriate therapies may slightly increase the risk of developing malignant diseases.
  • Many commercial hormonal compounds are currently available and the safest HRT regimen with regard to cancer risk must be identified.
  • It is equally important that the best strategies for breast and endometrial surveillance in women commencing HRT be outlined, bearing in mind that the diffusion of hormonal therapies may be halted by unnecessary medical interventions.
  • [MeSH-major] Breast Neoplasms / chemically induced. Endometrial Neoplasms / chemically induced. Hormone Replacement Therapy / adverse effects

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  • (PMID = 10515669.001).
  • [ISSN] 0378-5122
  • [Journal-full-title] Maturitas
  • [ISO-abbreviation] Maturitas
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] IRELAND
  • [Number-of-references] 33
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10. Griffiths F: Women's control and choice regarding HRT. Soc Sci Med; 1999 Aug;49(4):469-81
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Women's control and choice regarding HRT.
  • The promotion and use of hormone replacement therapy (HRT) is the focus of much medical activity and a social phenomenon studied by sociology.
  • The decision to prescribe HRT by a doctor may be a response to a woman's distress and is a decision involving uncertainty about risks and benefits.
  • Sociological analysis has seen the promotion and use of HRT as medicalisation of the menopause.
  • Through individual interviews and focus groups, this study hears from women how they approach the decision to take HRT or not, and what influences them.
  • The interviews reveal how women who dislike medication in general may consider HRT, influenced by fear of ill health which may be enhanced by the experience of illness in the family and by medical advice.
  • For the women the media and their social contacts were the major sources of information about HRT.
  • In the focus groups the women explored the control they had over the choice to take HRT and what limited this control and they explored the uncertainties and complexities of the decision to take HRT or not.
  • This study brings lay women's voices to the debate about the use and promotion of HRT.
  • The results are also used to test the limits of the theory of medicalisation and to inform doctors of the issues women may bring to a consultation about HRT.
  • [MeSH-major] Attitude to Health. Decision Making. Estrogen Replacement Therapy / psychology. Patient Participation

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  • (PMID = 10414807.001).
  • [ISSN] 0277-9536
  • [Journal-full-title] Social science & medicine (1982)
  • [ISO-abbreviation] Soc Sci Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
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