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1. Luciano TF, de Oliveira Marques S, da Silva Pieri BL, Roxo de Souza D, Araújo LV, Nesi RT, da Luz Scheffer D, Comin VH, Pinho RA, Muller AP, de Souza CT: Responses of skeletal muscle hypertrophy in Wistar rats to different resistance exercise models. Physiol Res; 2016 Dec 16;
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  • Twenty-four male Wistar rats were divided into untrained (control), endurance resistance training, strength resistance training, and hypertrophy resistance training (HRT) groups (n = 6).
  • However, the HRT group presented better results than the other two experimental groups.
  • In summary, our study showed that HRT leads to high levels of mTOR phosphorylation as well as of other proteins involved in the upstream regulation of mTOR.


2. De Sanctis V, Soliman AT, Elsedfy H, Albu A, Al Jaouni S, Anastasi S, Bisconte MG, Canatan D, Christou S, Daar S, Di Maio S, El Kholy M, Khater D, Elshinawy M, Kilinc Y, Mattei R, Mosli HH, Quota A, Roberti MG, Sobti P, Yaarubi SA, Canpisi S, Kattamis C: Review and Recommendations on Management of Adult Female Thalassemia Patients with Hypogonadism based on Literature Review and Experience of ICET-A Network Specialists. Mediterr J Hematol Infect Dis; 2017;9(1):e2017001
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  • Also to be aware of the side effects, contraindications and monitoring of sex steroid therapy.
  • RESULTS: The completed questionnaires were returned by 16 of 27 specialists (59.2%) following 590 female TM patients over the age of 18 years; 315 patients (53.3%) had hypogonadism, and only 245 (74.6%) were on hormone replacement therapy (HRT).
  • The frequency of required tests for follow-up HRT, in addition to the regular check-up for thalassemia, was variable in the participating centers.
  • They should know the potential effects of HRT including advantages and disadvantages of estrogen and progestins.

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  • (PMID = 28101307.001).
  • [Journal-full-title] Mediterranean journal of hematology and infectious diseases
  • [ISO-abbreviation] Mediterr J Hematol Infect Dis
  • [Language] eng
  • [Publication-type] Review; Journal Article
  • [Publication-country] Italy
  • [Keywords] NOTNLM ; Thalassemia / benefits and disadvantages / hormone replacement therapy / hypogonadism
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3. Kaneko S, Murota H, Murata S, Katayama I, Morita E: Usefulness of Sweat Management for Patients with Adult Atopic Dermatitis, regardless of Sweat Allergy: A Pilot Study. Biomed Res Int; 2017;2017:8746745
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  • Participant responses were compared with histamine release tests (HRT).
  • </i> Sweat HRT results were class ≥ 2 in 13 patients, but HRT results were not correlated with the patients' self-assessments of symptom aggravation by sweat.
  • [MeSH-major] Dermatitis, Atopic / therapy. Hypersensitivity / therapy. Sweat / secretion
  • [MeSH-minor] Adult. Female. Histamine Release. Humans. Male

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  • (PMID = 28210628.001).
  • [ISSN] 2314-6141
  • [Journal-full-title] BioMed research international
  • [ISO-abbreviation] Biomed Res Int
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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4. Balasubramanian M, Bowd C, Weinreb RN, Zangwill LM: Agreement between the Heidelberg Retina Tomograph (HRT) stereometric parameters estimated using HRT-I and HRT-II. Optom Vis Sci; 2011 Jan;88(1):140-9
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  • [Title] Agreement between the Heidelberg Retina Tomograph (HRT) stereometric parameters estimated using HRT-I and HRT-II.
  • PURPOSE: To assess agreement between Heidelberg Retina Tomograph (HRT)-I and HRT-II stereometric parameters and to determine whether parabolic error correction (PEC) to the topographies improves agreement.
  • METHODS: University of California San Diego Diagnostic Innovations in Glaucoma Study participants with two HRT-II examinations (n = 380) or one HRT-I and one HRT-II examinations (n = 344) acquired on the same day were included.
  • From the group of 380 eyes, 200 eyes were randomly selected to estimate the repeatability coefficients of HRT-II rim area and volume, cup area and volume, and mean retinal nerve fiber layer (RNFL) thickness parameters (HRT-II control group), and the remaining 180 eyes were used to assess agreement between two HRT-II examinations (HRT-II study group).
  • Agreement between stereometric parameters of HRT-I and HRT-II examinations (HRT-I vs. HRT-II study group) were assessed with (1) no PEC, (2) HRT PEC, and (3) a modified PEC.
  • RESULTS: In the HRT-II study group, agreement between stereometric parameters was good, with no statistically significant biases.
  • In the HRT-I vs. HRT-II study group, there was a small statistically significant bias between the stereometric parameters, but all differences were within CLA for ≥95% of participants.
  • CONCLUSIONS: Agreement between HRT-I and HRT-II stereometric parameters was good, and PEC did not improve agreement.
  • These results suggest that HRT-I and HRT-II examinations can be used interchangeably to detect changes in stereometric parameters over time.

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  • (PMID = 21037499.001).
  • [ISSN] 1538-9235
  • [Journal-full-title] Optometry and vision science : official publication of the American Academy of Optometry
  • [ISO-abbreviation] Optom Vis Sci
  • [Language] ENG
  • [Grant] United States / NEI NIH HHS / EY / EY011008-15; United States / NEI NIH HHS / EY / R01 EY011008; United States / NEI NIH HHS / EY / R01 EY011008-15; United States / NEI NIH HHS / EY / EY011008-14; United States / NEI NIH HHS / EY / K99 EY020518; United States / NEI NIH HHS / EY / EY11008; United States / NEI NIH HHS / EY / R01 EY011008-14
  • [Publication-type] Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS252970; NLM/ PMC3014384
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5. Rahman O, McGuire J, Storch EA, Lewin AB: Preliminary Randomized Controlled Trial of Habit Reversal Training for Treatment of Hair Pulling in Youth. J Child Adolesc Psychopharmacol; 2017 Mar;27(2):132-139
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • OBJECTIVES: This study evaluated the treatment efficacy of habit reversal training (HRT) relative to treatment as usual (TAU) for children and adolescents aged 7-17 years with a primary diagnosis of trichotillomania (TTM).
  • Participants (N = 40, 85% female) meeting diagnostic criteria for TTM were randomized to either 8 weekly sessions of HRT by trained therapists or 8 weeks of TAU.
  • One week after the final HRT session or final TAU week, patients completed a posttreatment assessment, followed by 1- and 3-month follow-up assessments.
  • RESULTS: The group by time analysis of variance yielded a significant interaction on the National Institute of Mental Health-Trichotillomania Severity Scale Total Score (F<sub>1,38</sub> = 16.47, p < 0.001, η<sup>2</sup><sub>p</sub> = 0.30).
  • The mean score decreased from 12.67 ± 4.60 at baseline to 5.62 ± 4.38 at posttreatment in the HRT group (t<sub>20</sub> = 5.99, p < 0.001, d = 1.31), whereas the TAU group changed from 10.42 ± 4.35 to 9.32 ± 4.11 (t<sub>18</sub> = 1.34, p = 0.20, d = 0.31).
  • The Massachusetts General Hospital-Hair Pulling Scale Total Score decreased from 15.14 ± 3.86 at baseline to 7.14 ± 5.54 at posttreatment in the HRT group (t<sub>20</sub> = 6.16, p < 0.001, d = 1.34); the TAU group changed from 14.16 ± 4.51 to 12.26 ± 4.34 (t<sub>18</sub> = 1.50, p = 0.15, d = 0.34).
  • On the Clinical Global Impressions-Improvement, 16/21 participants (76%) were rated as treatment responders in the HRT group versus 4/19 (21%) in the TAU group (χ<sup>2</sup> = 12.13, p < 0.001, V = 0.55).
  • CONCLUSIONS: HRT can be an effective treatment for TTM in youth.

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  • (PMID = 28005403.001).
  • [ISSN] 1557-8992
  • [Journal-full-title] Journal of child and adolescent psychopharmacology
  • [ISO-abbreviation] J Child Adolesc Psychopharmacol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; habit reversal training / hair pulling / trichotillomania
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6. Compston JE: The risks and benefits of HRT. J Musculoskelet Neuronal Interact; 2004 Jun;4(2):187-90
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  • [Title] The risks and benefits of HRT.
  • For many years hormone replacement therapy (HRT) was regarded as the gold standard for treatment of osteoporosis.
  • The current consensus is that HRT is no longer regarded as a front-line option for prevention of osteoporotic fractures and that its use for this purpose should be restricted to women with osteoporosis who have menopausal symptoms and to older women who are intolerant of other therapies and/or express a strong preference for HRT despite being informed about potential adverse effects.
  • Nevertheless, the mechanisms by which estrogen exerts its beneficial skeletal effects remain a major area of research that has important implications for the development of novel therapies.
  • [MeSH-major] Breast Neoplasms / epidemiology. Cardiovascular Diseases / epidemiology. Estrogen Replacement Therapy / adverse effects. Osteoporosis / drug therapy

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  • (PMID = 15615123.001).
  • [ISSN] 1108-7161
  • [Journal-full-title] Journal of musculoskeletal & neuronal interactions
  • [ISO-abbreviation] J Musculoskelet Neuronal Interact
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Greece
  • [Number-of-references] 25
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7. Pinto-Almazán R, Segura-Uribe JJ, Farfán-García ED, Guerra-Araiza C: Effects of Tibolone on the Central Nervous System: Clinical and Experimental Approaches. Biomed Res Int; 2017;2017:8630764
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  • Hormone replacement therapy (HRT) increases the risk of endometrial and breast cancer.
  • Although there are few studies on the effect of this hormone in the CNS, it has been reported that TIB decreases lipid peroxidation levels and improves memory and learning.
  • TIB has important neuroprotective effects that could prevent the risk of neurodegenerative diseases in postmenopausal women as well as the benefits of HRT in counteracting hot flashes, improving mood, and libido.
  • [MeSH-minor] Climacteric / drug effects. Cognition Disorders / drug therapy. Humans. Neuronal Plasticity / drug effects. Oxidative Stress / drug effects

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  • (PMID = 28191467.001).
  • [ISSN] 2314-6141
  • [Journal-full-title] BioMed research international
  • [ISO-abbreviation] Biomed Res Int
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Norpregnenes; FF9X0205V2 / tibolone
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8. Naumann DN, Mellis C, Smith IM, Mamuza J, Skene I, Harris T, Midwinter MJ, Hutchings SD: Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study. BMJ Open; 2016 Dec 21;6(12):e014162
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  • [Title] Safety and feasibility of sublingual microcirculation assessment in the emergency department for civilian and military patients with traumatic haemorrhagic shock: a prospective cohort study.
  • OBJECTIVES: Sublingual microcirculatory monitoring for traumatic haemorrhagic shock (THS) may predict clinical outcomes better than traditional blood pressure and cardiac output, but is not usually performed until the patient reaches the intensive care unit (ICU), missing earlier data of potential importance.
  • This pilot study assessed for the first time the feasibility and safety of sublingual video-microscopy for THS in the emergency department (ED), and whether it yields useable data for analysis.
  • PARTICIPANTS: There were 15 casualties (2 military, 13 civilian) who presented with traumatic haemorrhagic shock with a median injury severity score of 26.
  • CONCLUSIONS: Early sublingual microcirculatory monitoring in the ED for patients with THS is safe and feasible, even in a deployed military setting, and yields videos of satisfactory quality in a high proportion of cases.

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  • [Copyright] Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
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  • (PMID = 28003301.001).
  • [ISSN] 2044-6055
  • [Journal-full-title] BMJ open
  • [ISO-abbreviation] BMJ Open
  • [Language] eng
  • [Databank-accession-numbers] ClinicalTrials.gov/ NCT02111109
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Microcirculation / TRAUMA MANAGEMENT / haemorrhage / shock / sublingual
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9. Paudel S, Kang Y, Yoo YS, Seo GT: Effect of volumetric organic loading rate (OLR) on H&lt;sub&gt;2&lt;/sub&gt; and CH&lt;sub&gt;4&lt;/sub&gt; production by two-stage anaerobic co-digestion of food waste and brown water. Waste Manag; 2017 Mar;61:484-493
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effect of volumetric organic loading rate (OLR) on H<sub>2</sub> and CH<sub>4</sub> production by two-stage anaerobic co-digestion of food waste and brown water.
  • The aim of this study is to determine optimum Hydraulic Retention Time (HRT) of the two-stage anaerobic digester system for hydrogen and methane production.
  • This paper also discusses the effect of OLR with change in HRT on the system.
  • Four different HRTs of 48, 24, 12, 8h were monitored for acidogenic reactor, which provided OLR of 17.7, 34.8, 70.8, 106gVS/L·d respectively.
  • Two HRTs of 15days and 20days were studied with OLR of 1.24 and 1.76gVS/L·d respectively in methanogenic reactor.
  • Hydrogen production at higher OLR and shorter HRT seemed favorable 106gVS/L·d (8h) in acidogenic reactor system.
  • In methanogenic reactor system HRT of 20day with OLR of 1.24gVS/L·d was found optimum in terms of methane production and organic removal.
  • The result of this study illustrated the optimum HRT of 8h and 20days in acidogenic stage and methanogenic stage for maximum hydrogen and methane production.

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  • [Copyright] Copyright © 2016 Elsevier Ltd. All rights reserved.
  • (PMID = 28017551.001).
  • [ISSN] 1879-2456
  • [Journal-full-title] Waste management (New York, N.Y.)
  • [ISO-abbreviation] Waste Manag
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Anaerobic co-digestion / Brown water / Food waste / Hydrogen / Methane / Organic loading / Two-stage system
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10. Ismail MM, Essam TM, Ragab YM, El-Sayed AE, Mourad FE: Remediation of a mixture of analgesics in a stirred-tank photobioreactor using microalgal-bacterial consortium coupled with attempt to valorise the harvested biomass. Bioresour Technol; 2017 May;232:364-371
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • A hydraulic retention time (HRT) of 3days supported poor treatment because of the formation of p-aminophenol (paracetamol toxic metabolite).
  • Increasing the HRT to 4days enhanced the bioremediation efficiency.
  • However, shortening the HRT again to 3days neither improved the COD reduction nor ketoprofen removal.

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  • [Copyright] Copyright © 2017 Elsevier Ltd. All rights reserved.
  • (PMID = 28254731.001).
  • [ISSN] 1873-2976
  • [Journal-full-title] Bioresource technology
  • [ISO-abbreviation] Bioresour. Technol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Antioxidants / Biofuel / Bioremediation / Chlorella / Wastewater
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