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1. Taverna G, Corinti M, Colombo P, Grizzi F, Severo M, Piccinelli A, Giusti G, Benetti A, Zucali PA, Graziotti P: Bladder metastases of appendiceal mucinous adenocarcinoma: a case presentation. BMC Cancer; 2010;10:62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Bladder metastases of appendiceal mucinous adenocarcinoma: a case presentation.
  • BACKGROUND: Appendiceal adenocarcinoma is rare with a frequency of 0.08% of all surgically removed appendices.
  • Few cases of appendiceal carcinoma infiltrating the bladder wall for spatial contiguity have been documented.
  • CASE PRESENTATION: A case is reported of a 45-years old woman with mucinous cystadenocarcinoma of the appendix with bladder metastasis.
  • Histopathology of the transurethral bladder resection revealed a bladder adenocarcinoma [6 cm (at the maximum diameter) x 2,5 cm; approximate weight: 10 gr] with focal mucinous aspects penetrating the muscle and perivisceral fat.
  • Laparotomy evidenced the presence of a solid mass of the appendix (2,5 cm x 3 cm x 2 cm) extending to the loco-regional lymph nodes.
  • The subsequent pathological examination revealed a mucinous cystadenocarcinoma of the appendix with metastatic cells colonising the anterior bladder wall and several colic lymph nodes.
  • CONCLUSIONS: The rarity of the appendiceal carcinoma invading the urinary bladder and its usual involvement of nearest organs and the posterior bladder wall, led us to describe this case which demonstrates the ability of the appendiceal cancer to metastasize different regions of urinary bladder.
  • [MeSH-major] Appendiceal Neoplasms / pathology. Cystadenocarcinoma, Mucinous / secondary. Urinary Bladder Neoplasms / secondary

  • MedlinePlus Health Information. consumer health - Bladder Cancer.
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  • (PMID = 20178637.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC2836301
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2. Kılıç MÖ, İnan A, Bozer M: Four mucinous cystadenoma of the appendix treated by different approaches. Ulus Cerrahi Derg; 2014;30(2):97-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Four mucinous cystadenoma of the appendix treated by different approaches.
  • Appendiceal mucocele is a rare clinical entity characterized by dilatation of the appendiceal lumen due to abnormal mucinous secretion.
  • It may occur as a result of mucoceles, mucosal hyperplasia, mucinous cystadenoma or mucinous cystadenocarcinoma.
  • Mucinous cystadenoma of the appendix is the most common form, although it manifests itself in many different clinical presentations.
  • Preoperative diagnosis is difficult, and it is often detected at laparotomy.
  • In this article, we discussed four patients with appendix mucinous cystadenoma where different surgical methods were applied in light of the literature.

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  • (PMID = 25931904.001).
  • [ISSN] 1300-0705
  • [Journal-full-title] Ulusal cerrahi dergisi
  • [ISO-abbreviation] Ulus Cerrahi Derg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Turkey
  • [Other-IDs] NLM/ PMC4379824
  • [Keywords] NOTNLM ; Mucocele / appendix / cystadenoma
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4. Hassan S, Dhebri A, Lin L, Haque M: Appendiceal mucocele: a missed diagnosis. BMJ Case Rep; 2013;2013
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Appendiceal mucocele: a missed diagnosis.
  • In view of persistent pain and recurrent admissions a CT scan was arranged which showed a dilated retrocaecal appendix suggesting recurrent appendicitis.
  • Further to CT findings the patient underwent an urgent appendicectomy for a presumed diagnosis of chronic appendicitis but histology in fact revealed a cystoadenoma of appendix.
  • It is important to note that in this case the diagnosis of appendiceal mucocele was not considered therefore not particularly accounted for during surgery.
  • Has this been a malignant cystadenocarcinoma any spillage of malignant cells into the abdominal cavity during the operation could have a grave impact on long-term recovery and prognosis.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Cystadenoma, Mucinous / diagnosis
  • [MeSH-minor] Adult. Appendectomy. Delayed Diagnosis. Humans. Male

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  • (PMID = 23314881.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3603825
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5. Rabie ME, Al Shraim M, Al Skaini MS, Alqahtani S, El Hakeem I, Al Qahtani AS, Malatani T, Hummadi A: Mucus containing cystic lesions "mucocele" of the appendix: the unresolved issues. Int J Surg Oncol; 2015;2015:139461
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucus containing cystic lesions "mucocele" of the appendix: the unresolved issues.
  • BACKGROUND: Mucocele of the appendix is a rare condition, the pathological classification and management strategy of which have not been standardized yet.
  • AIM: To report on our management of appendiceal mucocele, highlighting the pitfalls and possible means for avoiding them.
  • MATERIALS AND METHODS: Our registries were reviewed to retrieve cases of appendiceal mucocele, encountered in the period from July 2008 to May 2013.
  • Abdominal ultrasound (US) and computerized axial tomography scan (CT) suspected the diagnosis in only one case each.
  • Open appendectomy was done in two cases of mucinous cystadenoma with no further surgery performed, despite the positive margin in one.
  • Laparoscopic appendectomy was done in three cases: mucinous cystadenoma in one case which needed no further surgery, mucinous cystadenocarcinoma with pseudomyxoma peritonei in another, and low grade mucinous tumour in a third case, and all needed subsequent right hemicolectomy.
  • Exploratory laparotomy was done in three cases: of these, synchronous right hemicolectomy was done in one case of mucinous cystadenoma/?mucinous tumour of uncertain malignant potential; in the other two cases, appendectomy only was done for mucinous hyperplasia with carcinoid tumour of the appendix in one case and mucinous cystadenoma/?mucinous tumour of uncertain malignant potential in another.
  • The 9th case was discovered upon laparoscopy for cholecystectomy; when pseudomyxoma peritonei arising from an appendiceal mucocele was found, laparoscopic appendectomy with peritoneal biopsy was then performed instead.
  • Histopathologic diagnostic uncertainty was present in two cases of mucinous cystadenoma where mucinous tumour of uncertain malignant potential was an alternative possibility.
  • CONCLUSION: Mucocele of the appendix should be considered in the differential diagnosis of cystic lesions in the right lower abdomen.
  • For mucinous cystadenocarcinoma, right hemicolectomy is usually needed, whereas for hyperplasia and cystadenoma, appendectomy usually suffices if the resection margins are free.
  • For mucinous tumours of uncertain malignant potential and low grade mucinous tumours as well as pseudomyxoma peritonei, the decision is not as simple.
  • [MeSH-major] Appendix. Cecal Diseases. Mucocele

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  • (PMID = 25878899.001).
  • [ISSN] 2090-1410
  • [Journal-full-title] International journal of surgical oncology
  • [ISO-abbreviation] Int J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4386699
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6. Mastoraki A, Sakorafas G, Vassiliu P, Contopoulou C, Arkadopoulos N: Mucocele of the Appendix: Dilemmas in Differential Diagnosis and Therapeutic Management. Indian J Surg Oncol; 2016 Mar;7(1):86-90
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mucocele of the Appendix: Dilemmas in Differential Diagnosis and Therapeutic Management.
  • Mucocele of the appendix (AM) is a descriptive term for mucinous distension of the appendiceal lumen.
  • It refers to the progressive retrograde dilatation of the vermiform appendix.
  • We present three isolated cases of AM complicated by the development of acute inflammation of the appendix.
  • Currently, the assessment of appendiceal lesions relies heavily on Ultra Sonography (US) as the primary diagnostic tool.
  • Despite recent research on the therapeutic strategies against appendiceal neoplastic disorders, surgical resection appears the only potentially curative approach.
  • Even if laparoscopy has been successfully used to perform appendectomy, some concerns exist regarding its use in dealing with mucinous secreting lesions because of possible spillage of mucin intra-operatively.
  • The aim of this investigation was to analyze all cases of AM complicated by the development of acute inflammation of the appendix presented in our institution.
  • Clinical features, diagnostic approach and management algorithm for appendiceal lesions are also discussed.

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  • (PMID = 27065689.001).
  • [ISSN] 0975-7651
  • [Journal-full-title] Indian journal of surgical oncology
  • [ISO-abbreviation] Indian J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4811825 [Available on 03/01/17]
  • [Keywords] NOTNLM ; Appendiceal mucocele / Cystadenocarcinoma / Cystadenoma / Diagnostic approach / Surgical management
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