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1. Nash GM, Smith JD, Tang L, Weiser MR, Temple LK, O'Reilly E, Saltz LB, Guillem JG, Paty PB: Lymph Node Metastasis Predicts Disease Recurrence in a Single-Center Experience of 70 Stages 1-3 Appendix Cancers: A Retrospective Review. Ann Surg Oncol; 2015 Oct;22(11):3613-7
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  • [Title] Lymph Node Metastasis Predicts Disease Recurrence in a Single-Center Experience of 70 Stages 1-3 Appendix Cancers: A Retrospective Review.
  • BACKGROUND: Previous reports on the surgical management of appendix cancer show high recurrence rates among patients initially presenting with localized disease.
  • This study sought to characterize predictors of outcome among patients treated for stages 1-3 appendix cancer at the authors' institution.
  • METHODS: Patients with nonmetastatic appendix cancer undergoing definitive surgery at a single cancer center from 1994 to 2013 were retrospectively reviewed.
  • Patients with appendiceal adenomas, cystadenomas, or classical carcinoids were excluded from the study.
  • All were explored by an expert surgeon who had treated at least 20 appendiceal cancers.
  • These were smaller and more likely to present as acute appendicitis than appendiceal adenocarcinoma (AA), but were otherwise similar in clinical presentation and outcome.
  • The presence of lymph node (LN) metastasis was associated with a higher risk of recurrence than of stage 2 appendix cancer (78 vs. 4 % at 5 years; p < 0.0001).
  • Perforated appendix and T4 tumor stage were common but not associated with recurrence.

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  • [ErratumIn] Ann Surg Oncol. 2015 Dec;22 Suppl 3:S1613 [25862584.001]
  • (PMID = 25663593.001).
  • [ISSN] 1068-9265
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] ENG
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748; United States / NCI NIH HHS / CA / P30 CA008748
  • [Publication-type] Journal Article; Research Support, N.I.H., Extramural
  • [Publication-country] United States
  • [Other-IDs] NLM/ NIHMS782768 [Available on 10/01/16]; NLM/ PMC4878821 [Available on 10/01/16]
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2. Whitson MR, Mayo PH: Ultrasonography in the emergency department. Crit Care; 2016;20(1):227
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  • Some applications of POCUS unique to the emergency department include abdominal ultrasonography of the right upper quadrant and appendix, obstetric, testicular, soft tissue/musculoskeletal, and ocular ultrasonography.

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  • (PMID = 27523885.001).
  • [ISSN] 1466-609X
  • [Journal-full-title] Critical care (London, England)
  • [ISO-abbreviation] Crit Care
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4983783
  • [Keywords] NOTNLM ; Critical care / Emergency medicine / Ultrasound
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3. Flood L, Chang Kh, McAnena O: A rare case of Amyand's hernia presenting as an enterocutaneous fistula. J Surg Case Rep; 2010;2010(7):6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • The finding of the vermiform appendix in an inguinal hernia has an incidence of approximately 1%.
  • The clinical presentation varies, depending on the extent of inflammation of the appendix and is most often misdiagnosed as an incarcerated inguinal hernia.
  • She underwent laparotomy, which revealed that the appendix appeared inflamed, lay in the inguinal canal and was the origin of the enterocutaneous communication.

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  • [Copyright] © JSCR.
  • (PMID = 24946340.001).
  • [ISSN] 2042-8812
  • [Journal-full-title] Journal of surgical case reports
  • [ISO-abbreviation] J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3649149
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4. Karagin PH, Stenram U, Wadström T, Ljungh A: Helicobacter species and gut bacterial DNA in Meckel's diverticulum and the appendix. World J Gastroenterol; 2011 Sep 28;17(36):4104-8
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  • [Title] Helicobacter species and gut bacterial DNA in Meckel's diverticulum and the appendix.
  • Helicobacter pylori (H. pylori) was found in three, Enterobacter in 18, and Bacteroides in 19 out of 100 appendix samples by PCR.
  • Enterococcus was not found in any MD or appendix samples.
  • [MeSH-major] Appendicitis / microbiology. Appendix / microbiology. DNA, Bacterial / analysis. Helicobacter / genetics. Meckel Diverticulum / microbiology

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  • (PMID = 22039324.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] China
  • [Chemical-registry-number] 0 / DNA, Bacterial
  • [Other-IDs] NLM/ PMC3203361
  • [Keywords] NOTNLM ; Appendix / Helicobacter / Meckel’s diverticulum / Polymerase chain reaction
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5. Lee CH, Lee MR, Kim JC, Kang MJ, Jeong YJ: Torsion of a mucocele of the vermiform appendix: a case report and review of the literature. J Korean Surg Soc; 2011 Dec;81 Suppl 1:S47-50
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  • [Title] Torsion of a mucocele of the vermiform appendix: a case report and review of the literature.
  • Torsion of a mucocele of the vermiform appendix is an extremely rare condition and also a rare cause of an acute abdomen with a clinical presentation that is indistinguishable from acute appendicitis, and thus, the condition is diagnosed during operation.
  • The appendix had a pelvic position and the torsion was counterclockwise.
  • In addition, the torsion was associated with mucocele of the appendix, which was considered a secondary factor of torsion.

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  • (PMID = 22319738.001).
  • [ISSN] 2093-0488
  • [Journal-full-title] Journal of the Korean Surgical Society
  • [ISO-abbreviation] J Korean Surg Soc
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3267065
  • [Keywords] NOTNLM ; Appendectomy / Mucocele / Torsion abnormality
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6. Franciotta D, Gastaldi M, Benedetti L, Pesce G, Biagioli T, Lolli F, Costa G, Melis C, Andreetta F, Simoncini O, Giannotta C, Bazzigaluppi E, Fazio R, Bedin R, Ferraro D, Mariotto S, Ferrari S, Galloni E, De Riva V, Zardini E, Cortese A, Nobile-Orazio E: Diagnostics of dysimmune peripheral neuropathies. Neurol Sci; 2017 Oct;38(Suppl 2):243-247
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  • Main clinical information on dysimmune peripheral neuropathies, indications and limits of anti-ganglioside antibody testing, instructions for result interpretation, and an agreed laboratory protocol (Appendix) are reported for the communicative community of neurologists and clinical pathologists.

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  • (PMID = 29030769.001).
  • [ISSN] 1590-3478
  • [Journal-full-title] Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
  • [ISO-abbreviation] Neurol. Sci.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Italy
  • [Keywords] NOTNLM ; Laboratory diagnostics / Neurological autoimmune diseases / Peripheral nervous system
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7. Yilmaz M, Akbulut S, Kutluturk K, Sahin N, Arabaci E, Ara C, Yilmaz S: Unusual histopathological findings in appendectomy specimens from patients with suspected acute appendicitis. World J Gastroenterol; 2013 Jul 7;19(25):4015-22
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  • METHODS: The demographic and histopathological data of 1621 patients (≥ 16 years-old) who underwent appendectomy to treat an initial diagnosis of acute appendicitis between January 1999 and November 2011 were retrospectively assessed.
  • Microscopic findings were used to classify the patients under six categories: appendix vermiformis, phlegmonous appendicitis, gangrenous appendicitis, perforated appendicitis, supurative appendicitis, and unusual histopathologic findings.
  • The demographic and clinicopathologic characteristics of patients with unusual histopathologic findings were evaluated in detail, and re-analysis of archived resected appendix specimens was carried out.
  • RESULTS: A total of 912 males and 709 females, from 16 to 94 years old, were included in the study and comprised 789 cases of suppurative appendicitis, 370 cases of appendix vermiformis, 243 cases of perforated gangrenous appendicitis, 53 cases of flegmaneous appendicitis, 32 cases of gangrenous appendicitis, and 134 (8.3%) cases of unusual histopathological findings.
  • The unusual histopathological findings included fibrous obliteration (n = 62), enterobius vermicularis (n = 31), eosinophilic infiltration (n = 10), mucinous cystadenoma (n = 8), carcinoid tumor (n = 6), granulomatous inflammation (n = 5), adenocarcinoma (n = 4; one of them mucinous), and mucocele (n = 3), adenomatous polyp (n = 1), taenia sup (n = 1), ascaris lumbricoides (n = 1), appendiceal diverticula (n = 1), and B cell non-hodgkin lymphoma (n = 1).
  • None of the 11 patients with subsequent diagnosis of tumor were suspected of cancer prior to the appendectomy.
  • CONCLUSION: Even when the macroscopic appearance of appendectomy specimens is normal, histopathological assessment will allow early diagnosis of many unusual diseases.
  • [MeSH-major] Appendectomy. Appendicitis / pathology. Appendix / pathology

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  • (PMID = 23840147.001).
  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC3703189
  • [Keywords] NOTNLM ; Appendectomy specimens / Appendiceal malignancy / Appendicitis / Histopathology / Unusual findings
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8. Papadopoulos IN, Christodoulou S, Kokoropoulos P, Konstantudakis G, Economopoulos N, Leontara V: Perforated mucinous cystadenoma of the vermiform appendix: an overview in reasoning clinical decisions. BMJ Case Rep; 2011;2011
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  • [Title] Perforated mucinous cystadenoma of the vermiform appendix: an overview in reasoning clinical decisions.
  • Recent advances in the management of appendiceal mucinous neoplasms (AMN) such as peritonectomy combined with hyperthermic intraperitoneal chemotherapy have introduced new standards of care.
  • A 74-year-old woman was admitted with an appendiceal cystadenoma found in a preadmission CT scan.
  • However, the tumour was not documented by the in hospital investigation due to its perforation and its reduction in size.
  • A spontaneous perforation was suspected, but the accurate diagnosis was documented postoperatively by histopathology.
  • [MeSH-major] Appendiceal Neoplasms / diagnosis. Cystadenoma, Mucinous / diagnosis
  • [MeSH-minor] Aged. Appendix / pathology. Appendix / surgery. Biopsy. Colectomy / methods. Colonoscopy. Decision Making. Diagnosis, Differential. Female. Humans. Magnetic Resonance Imaging. Neoplasm Staging. Tomography, X-Ray Computed. Ultrasonography

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  • (PMID = 22689271.001).
  • [ISSN] 1757-790X
  • [Journal-full-title] BMJ case reports
  • [ISO-abbreviation] BMJ Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3166594
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9. Wani NA, Farooq M, Gojwari T, Kosar T: Perinephric abscess caused by ruptured retrocecal appendix: MDCT demonstration. Urol Ann; 2010 Jan;2(1):29-31
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  • [Title] Perinephric abscess caused by ruptured retrocecal appendix: MDCT demonstration.
  • Inflamed retrocecal appendix was seen on thick multiplanar reformat images with its tip at the lower extent of the abscess.
  • A ruptured retrocecal appendix was confirmed as the cause of the abscess.

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  • (PMID = 20842255.001).
  • [ISSN] 0974-7834
  • [Journal-full-title] Urology annals
  • [ISO-abbreviation] Urol Ann
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC2934582
  • [Keywords] NOTNLM ; Perinephric abscess / multidetector-row CT-MDCT / retrocecal appendicitis
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10. Yamana I, Kawamoto S, Inada K, Nagao S, Yoshida T, Yamashita Y: Clinical characteristics of 12 cases of appendiceal diverticulitis: a comparison with 378 cases of acute appendicitis. Surg Today; 2012 Apr;42(4):363-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Clinical characteristics of 12 cases of appendiceal diverticulitis: a comparison with 378 cases of acute appendicitis.
  • PURPOSE: Previous authors have suggested that a diverticulum of the vermiform appendix has a higher risk of perforation than acute appendicitis.
  • Therefore, this study compared appendiceal diverticulitis with acute appendicitis to explain the characteristics of appendiceal diverticulitis.
  • METHODS: Data for this study came from a retrospective analysis at the Department of Surgery at Fukuoka Tokushukai Hospital from January 2005 to June 2008.
  • Twelve cases of appendiceal diverticulitis and 378 cases of acute appendicitis were analyzed.
  • RESULTS: The patients with appendiceal diverticulitis were older than those with acute appendicitis (42.7 ± 15.4 vs. 29.1 ± 17.7; p = 0.009).
  • The white blood cell (WBC) level was lower (11332 ± 4658 vs. 14236 ± 3861; p = 0.011) and the CRP level was higher (8.65 ± 8.94 vs. 4.34 ± 6.34, p = 0.022) in those with appendiceal diverticulitis than in those with acute appendicitis.
  • A preoperative diagnosis for appendiceal diverticulitis was made in 4 out of 12 (33.3%) by ultrasonography (US).
  • The perforation rate was higher in appendiceal diverticulitis than that in acute appendicitis (33.3 vs. 9.8%; p = 0.009).
  • CONCLUSIONS: Appendiceal diverticulitis is more likely to perforate over the progression of the clinical course, which would mandate appendectomy when appendiceal diverticulitis is detected by US, even if the patient has no severe abdominal pain.
  • [MeSH-major] Appendectomy. Appendicitis / diagnosis. Appendix / pathology. Diverticulitis / diagnosis
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. C-Reactive Protein. Chi-Square Distribution. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies. Sex Factors. Statistics as Topic. Ultrasonography. Young Adult






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