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1. Giorgini E, Sabbatini S, Conti C, Rubini C, Rocchetti R, Re M, Vaccari L, Mitri E, Librando V: Vibrational mapping of sinonasal lesions by Fourier transform infrared imaging spectroscopy. J Biomed Opt; 2015;20(12):125003
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • In addition, they can sometimes be confused with the more common inflammatory polyps.
  • Therefore, an early and definitive diagnosis of this pathology is mandatory.
  • Progressing in our research on the study of oral cavity lesions, 15 sections consisting of inflammatory sinonasal polyps, benign Schneiderian papillomas, and sinonasal undifferentiated carcinomas were analyzed using FTIRI.
  • To allow a rigorous description of these pathologies and to gain objective diagnosis, the epithelial layer and the adjacent connective tissue of each section were separately investigated by following a multivariate analysis approach.

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  • (PMID = 26677069.001).
  • [ISSN] 1560-2281
  • [Journal-full-title] Journal of biomedical optics
  • [ISO-abbreviation] J Biomed Opt
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Lipids; Sinonasal undifferentiated carcinoma
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2. McKenna MT, Wang S, Nguyen TB, Burns JE, Petrick N, Summers RM: Strategies for improved interpretation of computer-aided detections for CT colonography utilizing distributed human intelligence. Med Image Anal; 2012 Aug;16(6):1280-92
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  • Computer-aided detection (CAD) systems have been shown to improve the diagnostic performance of CT colonography (CTC) in the detection of premalignant colorectal polyps.
  • CAD annotations on true lesions are incorrectly dismissed, and false positives are misinterpreted as true polyps.
  • Here, we conduct an observer performance study utilizing distributed human intelligence in the form of anonymous knowledge workers (KWs) to investigate human performance in classifying polyp candidates under different presentation strategies.
  • We evaluated 600 polyp candidates from 50 patients, each case having at least one polyp ≥6 mm, from a large database of CTC studies.
  • Each polyp candidate was labeled independently as a true or false polyp by 20 KWs and an expert radiologist.
  • We asked each labeler to determine whether the candidate was a true polyp after looking at a single 3D-rendered image of the candidate and after watching a video fly-around of the candidate.
  • We noted that performance degraded with increasing interpretation time and increasing difficulty, but distributed human intelligence performed better than our CAD classifier for "easy" and "moderate" polyp candidates.
  • [MeSH-major] Colonic Polyps / radiography. Colonography, Computed Tomographic / methods. Colorectal Neoplasms / radiography. Intestinal Polyps / radiography. Pattern Recognition, Automated / methods. Radiographic Image Interpretation, Computer-Assisted / methods

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  • [Copyright] Copyright © 2012. Published by Elsevier B.V.
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  • (PMID = 22705287.001).
  • [ISSN] 1361-8423
  • [Journal-full-title] Medical image analysis
  • [ISO-abbreviation] Med Image Anal
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / / ZIA CL040003-09
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ NIHMS387696; NLM/ PMC3443285
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3. Korbar B, Olofson AM, Miraflor AP, Nicka CM, Suriawinata MA, Torresani L, Suriawinata AA, Hassanpour S: Deep Learning for Classification of Colorectal Polyps on Whole-slide Images. J Pathol Inform; 2017;8:30
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  • [Title] Deep Learning for Classification of Colorectal Polyps on Whole-slide Images.
  • CONTEXT: Histopathological characterization of colorectal polyps is critical for determining the risk of colorectal cancer and future rates of surveillance for patients.
  • AIMS: We built an automatic image analysis method that can accurately classify different types of colorectal polyps on whole-slide images to help pathologists with this characterization and diagnosis.
  • SUBJECTS AND METHODS: Our method covers five common types of polyps (i.e., hyperplastic, sessile serrated, traditional serrated, tubular, and tubulovillous/villous) that are included in the US Multisociety Task Force guidelines for colorectal cancer risk assessment and surveillance.
  • RESULTS: Our evaluation shows that our method with residual network architecture achieves the best performance for classification of colorectal polyps on whole-slide images (overall accuracy: 93.0%, 95% confidence interval: 89.0%-95.9%).
  • CONCLUSIONS: Our method can reduce the cognitive burden on pathologists and improve their efficacy in histopathological characterization of colorectal polyps and in subsequent risk assessment and follow-up recommendations.

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  • (PMID = 28828201.001).
  • [ISSN] 2229-5089
  • [Journal-full-title] Journal of pathology informatics
  • [ISO-abbreviation] J Pathol Inform
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Keywords] NOTNLM ; Colorectal polyps / deep learning / digital pathology / histopathological characterization
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4. Du N, Wang X, Guo J, Xu M: Attraction Propagation: A User-Friendly Interactive Approach for Polyp Segmentation in Colonoscopy Images. PLoS One; 2016;11(5):e0155371
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  • [Title] Attraction Propagation: A User-Friendly Interactive Approach for Polyp Segmentation in Colonoscopy Images.
  • The article raised a user-friendly interactive approach-Attraction Propagation (AP) in segmentation of colorectal polyps.
  • Compared with other interactive approaches, the AP relied on only one foreground seed to get different shapes of polyps, and it can be compatible with pre-processing stage of Computer-Aided Diagnosis (CAD) under the systematically procedure of Optical Colonoscopy (OC).
  • [MeSH-major] Colonic Polyps / pathology. Colonoscopy / methods. Diagnosis, Computer-Assisted / methods. Software

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  • (PMID = 27191849.001).
  • [ISSN] 1932-6203
  • [Journal-full-title] PloS one
  • [ISO-abbreviation] PLoS ONE
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4871526
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5. Linguraru MG, Panjwani N, Fletcher JG, Summers RM: Automated image-based colon cleansing for laxative-free CT colonography computer-aided polyp detection. Med Phys; 2011 Dec;38(12):6633-42
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  • [Title] Automated image-based colon cleansing for laxative-free CT colonography computer-aided polyp detection.
  • PURPOSE: To evaluate the performance of a computer-aided detection (CAD) system for detecting colonic polyps at noncathartic computed tomography colonography (CTC) in conjunction with an automated image-based colon cleansing algorithm.
  • Cases were selected from a polyp-enriched cohort and included scans in which at least 90% of the solid stool was visually estimated to be tagged and each colonic segment was distended in either the prone or supine view.
  • RESULTS: The dataset comprised 38 CTC scans from prone and/or supine scans of 19 patients containing 44 polyps larger than 10 mm (22 unique polyps, if matched between prone and supine scans).
  • The results are robust on fine details around folds, thin-stool linings on the colonic wall, near polyps and in large fluid/stool pools.
  • The sensitivity of the CAD system is 70.5% per polyp at a rate of 5.75 false positives/scan without using the stool subtraction module.
  • [MeSH-major] Algorithms. Colon / diagnostic imaging. Colonic Polyps / diagnostic imaging. Colonography, Computed Tomographic / methods. Pattern Recognition, Automated / methods. Radiographic Image Enhancement / methods. Radiographic Image Interpretation, Computer-Assisted / methods

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  • (PMID = 22149845.001).
  • [ISSN] 0094-2405
  • [Journal-full-title] Medical physics
  • [ISO-abbreviation] Med Phys
  • [Language] eng
  • [Grant] United States / Intramural NIH HHS / /
  • [Publication-type] Journal Article; Research Support, N.I.H., Intramural
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Laxatives
  • [Other-IDs] NLM/ PMC3254579
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6. Thomson M, Venkatesh K, Elmalik K, van der Veer W, Jaacobs M: Double balloon enteroscopy in children: diagnosis, treatment, and safety. World J Gastroenterol; 2010 Jan 7;16(1):56-62
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  • [Title] Double balloon enteroscopy in children: diagnosis, treatment, and safety.
  • METHODS: Fourteen patients (10 males) with a median age of 12.9 years (range 8.1-16.7) underwent DBE; 5 for Peutz-Jeghers syndrome (PJ syndrome), 2 for chronic abdominal pain, 4 for obscure gastrointestinal (GI) bleeding, 2 with angiomatous malformations (1 blue rubber bleb nevus syndrome) having persistent GI bleeding, and 1 with Cowden's syndrome with multiple polyps and previous intussusception.
  • Seven patients had both antegrade (trans-oral) and retrograde (trans-anal and via ileostomy) examinations.
  • Polyps were detected and successfully removed in all 5 patients with PJ syndrome, in a patient with tubulo-villous adenoma of the duodenum, in a patient with significant anemia and occult bleeding, and in a patient with Cowden's syndrome.
  • A diagnosis was made in a patient with multiple angiomata not amenable to endotherapy, and in 1 with a discrete angioma which was treated with argon plasma coagulation.
  • [MeSH-major] Endoscopy, Gastrointestinal / methods. Intestinal Diseases / diagnosis. Intestinal Diseases / therapy. Intestine, Small / pathology

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  • [ISSN] 2219-2840
  • [Journal-full-title] World journal of gastroenterology
  • [ISO-abbreviation] World J. Gastroenterol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Other-IDs] NLM/ PMC2799917
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7. Birk JW, Tadros M, Moezardalan K, Nadyarnykh O, Forouhar F, Anderson J, Campagnola P: Second harmonic generation imaging distinguishes both high-grade dysplasia and cancer from normal colonic mucosa. Dig Dis Sci; 2014 Jul;59(7):1529-34
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  • CONCLUSIONS: SHG signal intensity can differentiate malignant from non-malignant colonic polyp tissue with high sensitivity and specificity.
  • Anisotropic polarization can discern HGD from normal colonic polyp tissue.
  • [MeSH-minor] Anisotropy. Colonic Polyps / pathology. Diagnosis, Differential. Feasibility Studies. Humans. ROC Curve. Sensitivity and Specificity

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  • [ISSN] 1573-2568
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8. Oluyemi A, Awolola N, Oyedeji O: Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria. Pan Afr Med J; 2016;24:333
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  • [Title] Clinicopathologic review of polyps biopsied at colonoscopy in Lagos, Nigeria.
  • INTRODUCTION: Colorectal polyps are known precursors of colorectal cancers.
  • The aim of this study is to evaluate the clinicopathological profile of colorectal polyps biopsied during the inaugural 12 month period of colonoscopy from a private endoscopy suite in Nigeria.
  • METHODS: This is a retrospective review of all the clients who had polyps diagnosed at colonoscopy over a 12 month period (August 2014 -July 2015) at a private endoscopy suite in Lagos, Nigeria.
  • Of these, 14 individuals had a total of 18 polyps- 4 clients (28.6% of the persons with polyps) had two polyps each.
  • The polyp detection rate was 11.2% while the polyp per colonoscopy rate was 14.4%.
  • The presenting complaint at colonoscopy was hematochezia in 11 (78.6%), new onset constipation in 2 (14.2%) and peri-anal pain in 1 patient (7.1%).
  • The polyps were distributed as follows; 2 (11.1%) in the ascending colon, 1 (5.6%) each in the transverse and descending colons, 8 (44.4%) in the sigmoid colon, 6(33.3%) located in the rectum.
  • Pathologically, tubular (adenomatous) polyp with or without low grade dysplastic changes was diagnosed in 6 of the 18 polyps (giving an adenoma detection rate of 4.8%), 4 (22.2%) were inflammatory polyps, 1 (5.6%) was malignant and another had the rare inflammatory fibroid polyp.
  • CONCLUSION: The study supports the present wisdom that polyps are clearly less prevalent in our environment when compared to the Western world.
  • A case is also advanced for the increased deployment of endoscopy as a tool for the detection of these polyps and ultimately, the reduction of colorectal cancer in our population.
  • [MeSH-major] Adenoma / pathology. Colonic Polyps / pathology. Colonoscopy / methods. Colorectal Neoplasms / pathology
  • [MeSH-minor] Adult. Aged. Biopsy. Colitis / diagnosis. Colitis / epidemiology. Constipation / etiology. Female. Gastrointestinal Hemorrhage / etiology. Humans. Male. Middle Aged. Nigeria / epidemiology. Pain / etiology. Prevalence. Retrospective Studies

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  • [Journal-full-title] The Pan African medical journal
  • [ISO-abbreviation] Pan Afr Med J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Uganda
  • [Keywords] NOTNLM ; Nigeria / Polyps / adenoma / colonoscopy
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9. Summers RM: Polyp size measurement at CT colonography: what do we know and what do we need to know? Radiology; 2010 Jun;255(3):707-20
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  • [Title] Polyp size measurement at CT colonography: what do we know and what do we need to know?
  • Polyp size is a critical biomarker for clinical management.
  • Larger polyps have a greater likelihood of being or of becoming an adenocarcinoma.
  • To balance the referral rate for polypectomy against the risk of leaving potential cancers in situ, sizes of 6 and 10 mm are increasingly being discussed as critical thresholds for clinical decision making (immediate polypectomy versus polyp surveillance) and have been incorporated into the consensus CT Colonography Reporting and Data System (C-RADS).
  • Polyp size measurement at optical colonoscopy, pathologic examination, and computed tomographic (CT) colonography has been studied extensively but the reported precision, accuracy, and relative sizes have been highly variable.
  • This review summarizes current best practices for polyp size measurement, describes the role of automated size measurement software, discusses how to manage the measurement uncertainties, and identifies areas requiring further research.

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  • (PMID = 20501711.001).
  • [ISSN] 1527-1315
  • [Journal-full-title] Radiology
  • [ISO-abbreviation] Radiology
  • [Language] ENG
  • [Grant] United States / CLC NIH HHS / CL / Z01 CL040003
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Number-of-references] 76
  • [Other-IDs] NLM/ PMC2875919
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10. Goto H: Diagnosis and treatment of small bowel diseases are advanced by capsule endoscopy and double-balloon enteroscopy. Clin J Gastroenterol; 2010 Oct;3(5):219-25
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  • [Title] Diagnosis and treatment of small bowel diseases are advanced by capsule endoscopy and double-balloon enteroscopy.
  • DBE, which was developed by Yamamoto, employs two balloons combined with an overtube and allows deeper insertion into the small bowel, and can be a modality for examination of the entire small bowel with combined oral and anal approaches.
  • This modality enables biopsy specimens to be taken, polyps to be resected and hemostatic procedures to be performed throughout the small bowel.
  • The understanding of small bowel disease is being extended by using CE and DBE for diagnosis.

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  • (PMID = 26190324.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Capsule endoscopy / Double-balloon enteroscopy / Small bowel
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