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1. Uchiyama S, Ikenaga N, Haruyama Y, Nagaike K, Hotokezaka M, Kai M, Tanaka H, Chijiiwa K: Asymptomatic extra-adrenal paraganglioma masquerading as retroperitoneal sarcoma. Clin J Gastroenterol; 2010 Feb;3(1):13-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Asymptomatic extra-adrenal paraganglioma masquerading as retroperitoneal sarcoma.
  • A low-density nodule was detected in the left adrenal gland, 10 mm in diameter.
  • Retroperitoneal sarcoma and nonfunctional left adrenal tumor were suspected, and surgical treatment was performed.
  • Blood pressure normalized after excision of the tumor; thus, a diagnosis of paraganglioma was favored over that of retroperitoneal sarcoma.
  • The left adrenal gland was resected together with the adrenal tumor.
  • Extra-adrenal retroperitoneal paraganglioma was considered, and the adrenal tumor was diagnosed as cortical adenoma.
  • In patients with retroperitoneal tumor, even in the absence of clinical symptoms, we should keep in mind the possibility of extra-adrenal paraganglioma.

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  • (PMID = 26189900.001).
  • [ISSN] 1865-7257
  • [Journal-full-title] Clinical journal of gastroenterology
  • [ISO-abbreviation] Clin J Gastroenterol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Asymptomatic paraganglioma / Extra-adrenal paraganglioma / Retroperitoneal sarcoma / Retroperitoneal tumor
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2. King KS, Darmani NA, Hughes MS, Adams KT, Pacak K: Exercise-induced nausea and vomiting: another sign and symptom of pheochromocytoma and paraganglioma. Endocrine; 2010 Jun;37(3):403-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Exercise-induced nausea and vomiting: another sign and symptom of pheochromocytoma and paraganglioma.
  • A cohort of nine patients, mostly young adults, presented with a new sign/symptom of pheochromocytoma/paraganglioma: exercise-induced nausea and vomiting.
  • Following a 2000 report from a paraganglioma patient experiencing exercise-induced nausea and vomiting, we began asking patients about instances of nausea and vomiting with exercise.
  • A total of nine patients, 4.4% of our pheochromocytoma/paraganglioma population, presented with reports of exercise-induced nausea and vomiting, initially with moderate-to-intense levels of exercise, at the first presentation of their disease.
  • Exercise-induced nausea and vomiting should be considered a sign/symptom of pheochromocytoma/paraganglioma and should be addressed in the clinical evaluation of these patients, especially in young adults.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Exercise. Nausea / etiology. Paraganglioma / diagnosis. Pheochromocytoma / diagnosis. Vomiting / etiology


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4. Ramachandran R, Rewari V: Current perioperative management of pheochromocytomas. Indian J Urol; 2017 Jan-Mar;33(1):19-25
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  • Neuroendocrine tumors which have the potential to secrete catecholamines are either associated with sympathetic adrenal (pheochromocytoma) or nonadrenal (paraganglioma) tissue.

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  • (PMID = 28197025.001).
  • [ISSN] 0970-1591
  • [Journal-full-title] Indian journal of urology : IJU : journal of the Urological Society of India
  • [ISO-abbreviation] Indian J Urol
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] India
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5. Butt N, Salih M, Khan MR, Ahmed R, Haider Z, Shah SH: An incidentally discovered asymptomatic para-aortic paraganglioma with Peutz-Jeghers syndrome. Saudi J Gastroenterol; 2012 Nov-Dec;18(6):388-91
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An incidentally discovered asymptomatic para-aortic paraganglioma with Peutz-Jeghers syndrome.
  • CT scan guided left para-aortic lymph node biopsy revealed the characteristic features of extra-adrenal para-aortic paraganglioma.
  • Although cases of various GI and extra GI malignancies in PJS patients has been reported, the present case appears to be the first in literature in which the PJS syndrome was associated with asymptomatic extraadrenal para-aortic paraganglioma.
  • [MeSH-major] Incidental Findings. Jejunal Neoplasms / diagnosis. Paraganglioma / diagnosis. Peutz-Jeghers Syndrome / complications

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  • [Journal-full-title] Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
  • [ISO-abbreviation] Saudi J Gastroenterol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC3530995
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6. Crona J, Nordling M, Maharjan R, Granberg D, Stålberg P, Hellman P, Björklund P: Integrative genetic characterization and phenotype correlations in pheochromocytoma and paraganglioma tumours. PLoS One; 2014;9(1):e86756
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Integrative genetic characterization and phenotype correlations in pheochromocytoma and paraganglioma tumours.
  • BACKGROUND: About 60% of Pheochromocytoma (PCC) and Paraganglioma (PGL) patients have either germline or somatic mutations in one of the 12 proposed disease causing genes; SDHA, SDHB, SDHC, SDHD, SDHAF2, VHL, EPAS1, RET, NF1, TMEM127, MAX and H-RAS.
  • [MeSH-major] Adrenal Gland Neoplasms / genetics. Genes, Neoplasm / genetics. Paraganglioma / genetics. Phenotype. Pheochromocytoma / genetics


7. Chang RY, Lang BH, Wong KP, Lo CY: High pre-operative urinary norepinephrine is an independent determinant of peri-operative hemodynamic instability in unilateral pheochromocytoma/paraganglioma removal. World J Surg; 2014 Sep;38(9):2317-23
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] High pre-operative urinary norepinephrine is an independent determinant of peri-operative hemodynamic instability in unilateral pheochromocytoma/paraganglioma removal.
  • BACKGROUND: Peri-operative hemodynamic instability (HDI) may increase peri-operative morbidity in pheochromocytoma/paraganglioma (PPGL) patients.
  • [MeSH-major] Adrenal Gland Neoplasms / physiopathology. Adrenal Gland Neoplasms / urine. Norepinephrine / urine. Paraganglioma, Extra-Adrenal / physiopathology. Paraganglioma, Extra-Adrenal / urine. Pheochromocytoma / physiopathology. Pheochromocytoma / urine

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  • (PMID = 24782037.001).
  • [ISSN] 1432-2323
  • [Journal-full-title] World journal of surgery
  • [ISO-abbreviation] World J Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers; X4W3ENH1CV / Norepinephrine
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8. Snabboon T, Plengpanich W, Houngngam N, Buranasupkajorn P, Plengvidhya N, Sereepapong W, Sunthornyothin S, Shotelersuk V: Concurrent bilateral pheochromocytoma and thoracic paraganglioma during pregnancy. Endocrine; 2010 Apr;37(2):261-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent bilateral pheochromocytoma and thoracic paraganglioma during pregnancy.
  • After the fetal death, additional studies were performed and revealed a thoracic paraganglioma.
  • [MeSH-major] Adrenal Gland Neoplasms / complications. Mediastinal Neoplasms / complications. Paraganglioma / complications. Pheochromocytoma / complications. Pregnancy Complications, Neoplastic. von Hippel-Lindau Disease / complications


9. Hirai H, Midorikawa S, Suzuki S, Sasano H, Watanabe T, Satoh H: Somatostatin-secreting Pheochromocytoma Mimicking Insulin-dependent Diabetes Mellitus. Intern Med; 2016;55(20):2985-2991
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • : We herein present the findings of a 42-year-old woman with either adrenal pheochromocytoma or intraadrenal paraganglioma that simultaneously secreted somatostatin, thus mimicking insulin-dependent diabetes mellitus.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Adrenal Gland Neoplasms / secretion. Diabetes Mellitus, Type 1 / diagnosis. Pheochromocytoma / diagnosis. Pheochromocytoma / secretion. Somatostatin / secretion


10. Baez JC, Jagannathan JP, Krajewski K, O'Regan K, Zukotynski K, Kulke M, Ramaiya NH: Pheochromocytoma and paraganglioma: imaging characteristics. Cancer Imaging; 2012;12:153-62
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Pheochromocytoma and paraganglioma: imaging characteristics.
  • The accurate diagnosis of adult pheochromocytoma and paraganglioma necessitates a multidisciplinary approach that includes clinical history, biochemical testing, and multimodality imaging such as computed tomography, magnetic resonance imaging, and nuclear medicine studies.
  • [MeSH-major] Adrenal Gland Neoplasms / diagnosis. Paraganglioma / diagnosis. Pheochromocytoma / diagnosis. Soft Tissue Neoplasms / diagnosis

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  • (PMID = 22571874.001).
  • [ISSN] 1470-7330
  • [Journal-full-title] Cancer imaging : the official publication of the International Cancer Imaging Society
  • [ISO-abbreviation] Cancer Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Contrast Media; 0 / Radiopharmaceuticals
  • [Other-IDs] NLM/ PMC3362869
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