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1. Kawano K, Hattori Y, Iwakura H, Akamizu T, Maitani Y: Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma. Cancer Med; 2013 Jun;2(3):286-95
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  • [Title] Combination therapy with gefitinib and doxorubicin inhibits tumor growth in transgenic mice with adrenal neuroblastoma.
  • Highly relevant mouse models of human neuroblastoma (NB) are needed to evaluate new therapeutic strategies against NB.
  • In this study, we characterized transgenic mice with bilateral adrenal tumors.
  • On the basis of information from the tumoral gene expression profiles, we examined the antitumor effects of unencapsulated and liposomal doxorubicin (DXR), alone and in combination with gefitinib, on adrenal NB.
  • Immunohistochemical analysis revealed that the adrenal tumor vasculature with abundant pericyte coverage was a less leaky structure for liposomes.
  • In conclusion, the combination of gefitinib and DXR induces growth inhibition of adrenal NBs in transgenic mice.
  • [MeSH-major] Adrenal Gland Neoplasms / drug therapy. Antineoplastic Combined Chemotherapy Protocols / pharmacology. Neuroblastoma / drug therapy

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  • [Cites] Med Pediatr Oncol. 2001 Jan;36(1):127-31 [11464864.001]
  • [Cites] Clin Cancer Res. 2000 Dec;6(12):4885-92 [11156248.001]
  • [Cites] Nature. 2003 Aug 28;424(6952):1071-4 [12944971.001]
  • [Cites] Cancer Res. 2004 Oct 15;64(20):7491-9 [15492275.001]
  • [Cites] Cancer Res. 1986 Dec;46(12 Pt 1):6387-92 [2946403.001]
  • [Cites] Biochim Biophys Acta. 1990 Jun 27;1025(2):143-51 [2364073.001]
  • [Cites] Biol Pharm Bull. 1995 Sep;18(9):1234-7 [8845812.001]
  • [Cites] FEBS Lett. 1996 May 20;386(2-3):243-6 [8647291.001]
  • [Cites] Drugs. 1997;54 Suppl 4:15-21 [9361957.001]
  • [Cites] Clin Cancer Res. 2005 Feb 1;11(3):971-81 [15709162.001]
  • [Cites] Neuro Oncol. 2005 Oct;7(4):452-64 [16212810.001]
  • [Cites] Cancer Res. 2005 Nov 1;65(21):9868-75 [16267010.001]
  • [Cites] Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3460-5 [17307870.001]
  • [Cites] Biochem Biophys Res Commun. 2007 Jun 22;358(1):226-32 [17482563.001]
  • [Cites] Lancet. 2007 Jun 23;369(9579):2106-20 [17586306.001]
  • [Cites] Arch Otolaryngol Head Neck Surg. 2007 Oct;133(10):1022-7 [17938326.001]
  • [Cites] J Pediatr Hematol Oncol. 2007 Nov;29(11):799-803 [17984703.001]
  • [Cites] J Magn Reson Imaging. 2007 Dec;26(6):1618-25 [17968965.001]
  • [Cites] Cancer. 2008 Sep 15;113(6):1412-22 [18671248.001]
  • [Cites] Clin Cancer Res. 2008 Nov 15;14(22):7320-9 [19010847.001]
  • [Cites] Int J Oncol. 2008 Dec;33(6):1195-9 [19020752.001]
  • [Cites] Cancer Sci. 2009 Jan;100(1):173-80 [19037999.001]
  • [Cites] Cancer Res. 2009 Aug 1;69(15):6347-54 [19622766.001]
  • [Cites] Int J Cancer. 2009 Dec 1;125(11):2547-55 [19623650.001]
  • [Cites] Br J Cancer. 2009 Dec 1;101(11):1884-90 [19888220.001]
  • [Cites] Clin Cancer Res. 2010 Mar 1;16(5):1478-85 [20179224.001]
  • [Cites] J Control Release. 2010 Jul 1;145(1):66-73 [20346382.001]
  • [Cites] Int J Oncol. 2010 Sep;37(3):695-705 [20664939.001]
  • [Cites] Cancer Sci. 2010 Oct;101(10):2207-13 [20608940.001]
  • [Cites] PLoS One. 2011;6(4):e19133 [21559450.001]
  • [Cites] Clin Lab. 2011;57(9-10):781-4 [22029196.001]
  • [Cites] Invest New Drugs. 2012 Aug;30(4):1660-70 [21796439.001]
  • [Cites] Pharmacol Rev. 1999 Dec;51(4):691-743 [10581328.001]
  • [Cites] Carcinogenesis. 2000 Dec;21(12):2211-8 [11133810.001]
  • [Cites] Oncologist. 2003;8(3):278-92 [12773750.001]
  • (PMID = 23930205.001).
  • [ISSN] 2045-7634
  • [Journal-full-title] Cancer medicine
  • [ISO-abbreviation] Cancer Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Quinazolines; 0 / liposomal doxorubicin; 30IQX730WE / Polyethylene Glycols; 80168379AG / Doxorubicin; S65743JHBS / gefitinib
  • [Other-IDs] NLM/ PMC3699840
  • [Keywords] NOTNLM ; Adrenal neuroblastoma / doxorubicin / gefitinib / liposome / transgenic mouse
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2. Prasad R, Metherell LA, Clark AJ, Storr HL: Deficiency of ALADIN impairs redox homeostasis in human adrenal cells and inhibits steroidogenesis. Endocrinology; 2013 Sep;154(9):3209-18
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  • [Title] Deficiency of ALADIN impairs redox homeostasis in human adrenal cells and inhibits steroidogenesis.
  • Triple A syndrome is a rare, autosomal recessive cause of adrenal failure.
  • The AAAS gene product is the nuclear pore complex protein alacrima-achalasia-adrenal insufficiency neurological disorder (ALADIN), of unknown function.
  • To provide an adrenal and neuronal-specific disease model, we established AAAS-gene knockdown in H295R human adrenocortical tumor cells and SH-SY5Y human neuroblastoma cells by lentiviral short hairpin RNA transduction.
  • CONCLUSION: Our in vitro data in AAAS-knockdown adrenal and neuronal cells not only corroborates previous studies implicating oxidative stress in this disorder but also provides further insights into the pathogenic mechanisms in triple A syndrome.
  • [MeSH-major] Adrenal Cortex / metabolism. Adrenal Cortex Hormones / metabolism. Nerve Tissue Proteins / metabolism. Neurons / metabolism. Nuclear Pore Complex Proteins / metabolism. Oxidative Stress. Phosphoproteins / metabolism. Steroid 11-beta-Hydroxylase / metabolism
  • [MeSH-minor] Adrenal Insufficiency / drug therapy. Adrenal Insufficiency / etiology. Adrenal Insufficiency / metabolism. Antioxidants / pharmacology. Antioxidants / therapeutic use. Apoptosis / drug effects. Cell Line, Tumor. Cell Survival / drug effects. Down-Regulation / drug effects. Esophageal Achalasia / drug therapy. Esophageal Achalasia / etiology. Esophageal Achalasia / metabolism. Gene Knockdown Techniques. Glutathione / metabolism. Humans. Oxidants / pharmacology. Oxidation-Reduction. Protein Synthesis Inhibitors / pharmacology. Puromycin / pharmacology. RNA, Small Interfering

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  • [Cites] Lancet. 1978 Jun 17;1(8077):1284-6 [78049.001]
  • [Cites] J Clin Endocrinol Metab. 2009 Oct;94(10):3865-71 [19773404.001]
  • [Cites] Mol Endocrinol. 2009 Dec;23(12):2086-94 [19855093.001]
  • [Cites] Toxicol Sci. 2010 Apr;114(2):285-94 [20100736.001]
  • [Cites] Eur J Pediatr. 1995 Jan;154(1):18-23 [7895750.001]
  • [Cites] Nature. 1995 Jul 6;376(6535):37-43 [7596430.001]
  • [Cites] J Biol Chem. 1998 Dec 11;273(50):33533-9 [9837934.001]
  • [Cites] Endocr Res. 2004 Nov;30(4):891-9 [15666842.001]
  • [Cites] Neuroscience. 2005;131(1):113-23 [15680696.001]
  • [Cites] Cell. 2005 Apr 22;121(2):223-34 [15851029.001]
  • [Cites] Mol Cell Biol. 2006 Mar;26(5):1879-87 [16479006.001]
  • [Cites] Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2298-303 [16467144.001]
  • [Cites] Biochem Cell Biol. 2006 Apr;84(2):243-9 [16609705.001]
  • [Cites] Drug Metab Rev. 2006;38(1-2):171-96 [16684656.001]
  • [Cites] Ann Neurol. 2006 Aug;60(2):214-22 [16786527.001]
  • [Cites] Biochem Biophys Res Commun. 2008 Oct 3;374(4):631-4 [18662670.001]
  • [Cites] Am J Hum Genet. 2009 Jan;84(1):44-51 [19118815.001]
  • [Cites] Exp Mol Med. 2009 Jun 30;41(6):381-6 [19322026.001]
  • [Cites] Eur J Pediatr. 2010 Nov;169(11):1323-8 [20499090.001]
  • [Cites] J Mol Med (Berl). 2010 Dec;88(12):1233-42 [20706703.001]
  • [Cites] Curr Opin Pediatr. 2010 Dec;22(6):751-7 [21610332.001]
  • [Cites] PLoS One. 2011;6(5):e20178 [21647419.001]
  • [Cites] J Pediatr Endocrinol Metab. 1999 Apr;12 Suppl 1:277-93 [10698592.001]
  • [Cites] Endocr Res. 2000 Nov;26(4):751-9 [11196451.001]
  • [Cites] Hum Mol Genet. 2001 Feb 1;10(3):283-90 [11159947.001]
  • [Cites] J Cell Biol. 2002 Sep 2;158(5):915-27 [12196509.001]
  • [Cites] Brain. 2002 Dec;125(Pt 12):2681-90 [12429595.001]
  • [Cites] Am J Surg Pathol. 2003 May;27(5):667-72 [12717251.001]
  • [Cites] Proc Natl Acad Sci U S A. 2003 May 13;100(10):5823-7 [12730363.001]
  • [Cites] Cell Signal. 2011 Oct;23(10):1555-62 [21683138.001]
  • [Cites] J Neurol. 2012 Jan;259(1):39-46 [21656342.001]
  • [Cites] Cell Signal. 2012 May;24(5):981-90 [22286106.001]
  • [Cites] Mol Cell. 2012 Jun 8;46(5):584-94 [22681886.001]
  • [Cites] Nat Genet. 2012 Jul;44(7):740-2 [22634753.001]
  • [Cites] Biochim Biophys Acta. 2012 Sep;1822(9):1475-88 [22353463.001]
  • [Cites] Biochim Biophys Acta. 2012 Sep;1822(9):1465-74 [22483867.001]
  • [Cites] J Biol Chem. 2013 Apr 19;288(16):11509-19 [23467407.001]
  • [Cites] Endocrinology. 2003 Jul;144(7):2882-91 [12810543.001]
  • [Cites] Ann N Y Acad Sci. 2003 May;995:59-72 [12814939.001]
  • [Cites] BMC Ophthalmol. 2004;4:7 [15217518.001]
  • (PMID = 23825130.001).
  • [ISSN] 1945-7170
  • [Journal-full-title] Endocrinology
  • [ISO-abbreviation] Endocrinology
  • [Language] eng
  • [Grant] United Kingdom / Medical Research Council / / G0801265; United Kingdom / Medical Research Council / / MR/K020455/1; United Kingdom / Wellcome Trust / / WT095984AIA
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / AAAS protein, human; 0 / Adrenal Cortex Hormones; 0 / Antioxidants; 0 / Nerve Tissue Proteins; 0 / Nuclear Pore Complex Proteins; 0 / Oxidants; 0 / Phosphoproteins; 0 / Protein Synthesis Inhibitors; 0 / RNA, Small Interfering; 0 / steroidogenic acute regulatory protein; 4A6ZS6Q2CL / Puromycin; EC 1.14.15.4 / Steroid 11-beta-Hydroxylase; GAN16C9B8O / Glutathione; Achalasia Addisonianism Alacrimia syndrome
  • [Other-IDs] NLM/ PMC3958737
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3. Do AY, Kim JS, Choi SJ, Oh SY, Roh CR, Kim JH: Prenatal diagnosis of congenital mesoblastic nephroma. Obstet Gynecol Sci; 2015 Sep;58(5):405-8
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  • [Title] Prenatal diagnosis of congenital mesoblastic nephroma.
  • Differential diagnoses include Wilms tumor, adrenal neuroblastoma, and other abdominal tumors.

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  • (PMID = 26430667.001).
  • [ISSN] 2287-8572
  • [Journal-full-title] Obstetrics & gynecology science
  • [ISO-abbreviation] Obstet Gynecol Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4588847
  • [Keywords] NOTNLM ; Drug therapy / Nephroma, mesoblastic / Pregnancy / Prenatal diagnosis / Renal tumor
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4. Easton JC, Gomez S, Asdahl PH, Conner JM, Fynn AB, Ruiz C, Ojha RP: Survival of high-risk pediatric neuroblastoma patients in a developing country. Pediatr Transplant; 2016 Sep;20(6):825-30
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  • [Title] Survival of high-risk pediatric neuroblastoma patients in a developing country.
  • Little information is available about survival of high-risk pediatric neuroblastoma patients in developing countries.
  • We aimed to assess survival among high-risk pediatric neuroblastoma patients in La Plata, Argentina.
  • Individuals eligible for our cohort were aged <20 yr when diagnosed with high-risk neuroblastoma and received cancer-directed therapy including stem cell transplantation at Hospital de Niños Sor Maria Ludovica between February 1999 and February 2015.
  • Our study population comprised 39 high-risk neuroblastoma patients, of whom 39% were aged >4 yr at diagnosis, 54% were male, and 62% had adrenal neuroblastoma.
  • In contrast, five-yr survival of high-risk neuroblastoma patients ranges between 23% and 76% in developed countries.
  • Survival among high-risk neuroblastoma patients is generally poor regardless of geographic location, but our results illustrate dramatically worse survival for patients in a developing country.
  • [MeSH-major] Adrenal Gland Neoplasms / mortality. Mediastinal Neoplasms / mortality. Neuroblastoma / mortality. Retroperitoneal Neoplasms / mortality

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  • [Copyright] © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
  • [CommentIn] Pediatr Transplant. 2016 Sep;20(6):742-3 [27501322.001]
  • [Cites] AIDS. 2010 Oct 23;24(16):2423-31 [20827167.001]
  • [Cites] J Clin Oncol. 2009 Mar 1;27(7):1007-13 [19171716.001]
  • [Cites] Pediatr Clin North Am. 2015 Feb;62(1):225-56 [25435121.001]
  • [Cites] Pediatr Blood Cancer. 2005 Apr;44(4):348-57 [15546135.001]
  • [Cites] J Clin Oncol. 2006 Jun 20;24(18):2891-6 [16782928.001]
  • [Cites] Nutrition. 2003 Oct;19(10):823-5 [14559314.001]
  • [Cites] J Korean Med Sci. 2007 Sep;22 Suppl:S66-72 [17923758.001]
  • [Cites] Pediatr Blood Cancer. 2011 Dec 1;57(6):965-71 [21744481.001]
  • [Cites] Pediatr Blood Cancer. 2015 Sep;62(9):1529-35 [25810376.001]
  • [Cites] Bone Marrow Transplant. 2007 Oct;40(8):741-6 [17724446.001]
  • [Cites] Pediatr Blood Cancer. 2015 Feb;62(2):204-207 [25307693.001]
  • [Cites] Lancet Oncol. 2005 Sep;6(9):649-58 [16129365.001]
  • [Cites] Int J Cancer. 1992 Oct 21;52(4):538-43 [1399133.001]
  • [Cites] J Clin Oncol. 2015 Sep 20;33(27):3065-73 [26304881.001]
  • [Cites] J Pediatr Hematol Oncol. 2003 Jan;25(1):8-13 [12544767.001]
  • [Cites] Pediatr Blood Cancer. 2013 Jun;60(6):985-93 [23255319.001]
  • [Cites] Curr Opin Oncol. 2014 Nov;26(6):650-5 [25202926.001]
  • [Cites] Epidemiology. 2012 Jul;23(4):565-73 [22517300.001]
  • [Cites] Int J Hematol. 2003 Dec;78(5):383-9 [14704030.001]
  • [Cites] Oncotarget. 2016 Jan 26;7(4):4155-66 [26623730.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):858-62 [25245583.001]
  • [Cites] Pediatr Blood Cancer. 2014 Jun;61(6):977-81 [23970413.001]
  • [Cites] Curr Opin Pediatr. 2013 Feb;25(1):3-15 [23295716.001]
  • [Cites] J Clin Oncol. 2010 Jul 20;28(21):3516-24 [20567002.001]
  • [Cites] Singapore Med J. 2012 Jan;53(1):19-25 [22252178.001]
  • [Cites] Eur J Cancer. 2013 Jan;49(2):465-73 [22980725.001]
  • [Cites] Pediatr Blood Cancer. 2012 Nov;59(5):902-7 [22744917.001]
  • (PMID = 27235336.001).
  • [ISSN] 1399-3046
  • [Journal-full-title] Pediatric transplantation
  • [ISO-abbreviation] Pediatr Transplant
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / R25 CA023944
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] Denmark
  • [Keywords] NOTNLM ; developing country (major topic) / disparity (major topic) / mortality (major topic) / neuroblastoma (major topic) / stem cell transplantation (major topic)
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5. Le-Xiang Z, Yao-Hao W, Na L, Rong-Lin Q, Jia-Jia Z, Wen-Li J, Jie Z, Xiao-Geng D: Analysis of treatment of large abdominal malignancies in children complicated with abdominal compartment syndrome: Report of six cases. Medicine (Baltimore); 2017 Apr;96(17):e6705
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  • To explore effective treatment of large abdominal malignancies in children complicated with abdominal compartment syndrome (ACS).Six children with large abdominal malignancies complicated with ACS were admitted to our department from January 2013 to January 2016, and the changes in their breathing, heart rate, oxygen saturation, abdominal circumference, bladder pressure, and urine output, as well as the treatment measures and outcomes, were retrospectively analyzed.The 6 children included 1 child with bilateral nephroblastoma, 1 child with abdominal alveolar rhabdomyosarcoma, 1 child with right ovarian malignant teratoma complicated with abdominal glioma, 1 child with abdominal malignant teratoma, 1 child with right nephroblastoma, and 1 child with left adrenal gland neuroblastoma.
  • [MeSH-minor] Adrenal Gland Neoplasms / complications. Adrenal Gland Neoplasms / mortality. Adrenal Gland Neoplasms / physiopathology. Adrenal Gland Neoplasms / therapy. Child, Preschool. Emergency Treatment. Female. Follow-Up Studies. Glioma / complications. Glioma / mortality. Glioma / physiopathology. Glioma / therapy. Humans. Infant. Infant, Newborn. Male. Neuroblastoma / complications. Neuroblastoma / mortality. Neuroblastoma / physiopathology. Neuroblastoma / therapy. Retrospective Studies. Teratoma / complications. Teratoma / mortality. Teratoma / physiopathology. Teratoma / therapy. Treatment Outcome. Wilms Tumor / complications. Wilms Tumor / mortality. Wilms Tumor / physiopathology. Wilms Tumor / therapy

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  • [Cites] Ann Surg. 1984 Jan;199(1):28-30 [6691728.001]
  • [Cites] Crit Care Med. 2008 Jul;36(7):2157-62 [18552691.001]
  • [Cites] J Pediatr Surg. 2010 Jun;45(6):1324-9 [20620339.001]
  • [Cites] J Clin Diagn Res. 2014 Dec;8(12):PC06-7 [25653998.001]
  • [Cites] Crit Care. 2008;12(1):R4 [18197961.001]
  • [Cites] J Trauma. 1992 Aug;33(2):279-82; discussion 282-3 [1507294.001]
  • [Cites] Crit Care Med. 2005 Feb;33(2):315-22 [15699833.001]
  • [Cites] World J Surg. 2009 Feb;33(2):199-207 [19089494.001]
  • [Cites] Langenbecks Arch Surg. 2008 Nov;393(6):833-47 [18560882.001]
  • [Cites] Crit Care Med. 2000 Jun;28(6):1747-53 [10890613.001]
  • [Cites] Crit Care Med. 2010 Feb;38(2):402-7 [20095067.001]
  • (PMID = 28445278.001).
  • [ISSN] 1536-5964
  • [Journal-full-title] Medicine
  • [ISO-abbreviation] Medicine (Baltimore)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Observational Study
  • [Publication-country] United States
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6. Terrile M, Bryan K, Vaughan L, Hallsworth A, Webber H, Chesler L, Stallings RL: miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs. PLoS One; 2011;6(12):e28356
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  • [Title] miRNA expression profiling of the murine TH-MYCN neuroblastoma model reveals similarities with human tumors and identifies novel candidate miRNAs.
  • BACKGROUND: MicroRNAs are small molecules which regulate gene expression post-transcriptionally and aberrant expression of several miRNAs is associated with neuroblastoma, a childhood cancer arising from precursor cells of the sympathetic nervous system.
  • TH-MYCN is a well-characterized transgenic model of MYCN-driven neuroblastoma which recapitulates many clinicopathologic features of the human disease.
  • PRINCIPAL FINDINGS: We analyzed the expression of 591 miRNAs in control (adrenal) and neuroblastoma tumor tissues derived from either TH-MYCN or TH-MYCN/p53ER(TAM) mice, respectively wild-type or deficient in p53.
  • Using data previously obtained from human neuroblastoma samples, we performed a comparison of miRNA expression between murine and human tumors to assess the concordance between murine and human expression data.
  • SIGNIFICANCE: Our study represents the first miRNA profiling of an important mouse model of neuroblastoma.
  • Similarities and differences in miRNAs expression between human and murine neuroblastoma were identified, providing important insight into the efficacy of this mouse model for assessing miRNA involvement in neuroblastoma and their potential effectiveness as therapeutic targets.
  • [MeSH-major] Gene Expression Profiling. Gene Expression Regulation, Neoplastic. MicroRNAs / metabolism. Neuroblastoma / metabolism. Proto-Oncogene Proteins / genetics. Tumor Suppressor Protein p53 / genetics
  • [MeSH-minor] Adrenal Glands / metabolism. Animals. Cell Line, Tumor. Cluster Analysis. Disease Models, Animal. Humans. Mice. Mice, Transgenic. Signal Transduction


7. Watanabe Nemoto M, Isobe K, Togasaki G, Kanazawa A, Kurokawa M, Saito M, Harada R, Kobayashi H, Ito H, Uno T: Delayed renal dysfunction after total body irradiation in pediatric malignancies. J Radiat Res; 2014 Sep;55(5):996-1001
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  • The median age at the time of diagnosis was 6 years old (range: 1-17 years old).
  • The kidneys and the liver were not shielded except in one patient with a left adrenal neuroblastoma.
  • [MeSH-major] Hematopoietic Stem Cell Transplantation / adverse effects. Kidney Diseases / diagnosis. Kidney Diseases / etiology. Neoplasms / complications. Neoplasms / radiotherapy. Survivors. Whole-Body Irradiation / adverse effects

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  • [Copyright] © The Author 2014. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.
  • [Cites] Kidney Int. 2000 Aug;58(2):903-18 [10916120.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):539-46 [20133075.001]
  • [Cites] Bone Marrow Transplant. 2002 Jan;29(2):129-36 [11850707.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2002 Nov 15;54(4):1165-73 [12419445.001]
  • [Cites] Q J Med. 1971 Jan;40(157):145-57 [5090542.001]
  • [Cites] Pediatr Clin North Am. 1987 Jun;34(3):571-90 [3588043.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1988 Jul;15(1):99-104 [2968967.001]
  • [Cites] Transplant Proc. 1989 Feb;21(1 Pt 3):3092-4 [2650432.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1991 May 15;21(1):109-22 [2032882.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1992;23(3):681-6 [1612975.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1995 Mar 30;31(5):1249-56 [7713786.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 1996 Mar 1;34(4):843-51 [8598361.001]
  • [Cites] Bone Marrow Transplant. 1997 Dec;20(12):1069-74 [9466280.001]
  • [Cites] Ann Intern Med. 2004 Dec 21;141(12):929-37 [15611490.001]
  • [Cites] Strahlenther Onkol. 2005 Nov;181(11):704-8 [16254705.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2006 Jul 15;65(4):1228-32 [16682132.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2008 Aug 1;71(5):1436-43 [18355974.001]
  • [Cites] Radiother Oncol. 2009 Feb;90(2):242-6 [18973960.001]
  • [Cites] Ann Intern Med. 2009 May 5;150(9):604-12 [19414839.001]
  • [Cites] Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S108-15 [20171504.001]
  • [Cites] Bone Marrow Transplant. 2001 Feb;27(3):319-27 [11277181.001]
  • (PMID = 24914103.001).
  • [ISSN] 1349-9157
  • [Journal-full-title] Journal of radiation research
  • [ISO-abbreviation] J. Radiat. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4202299
  • [Keywords] NOTNLM ; long-term survivor / pediatrics / renal toxicity / total body irradiation
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8. Park KU, Prahlow JA: Sudden death due to adrenal neuroblastoma: child abuse mimic? Forensic Sci Med Pathol; 2011 Mar;7(1):47-52
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sudden death due to adrenal neuroblastoma: child abuse mimic?
  • Neuroblastoma is one of the most common malignancies in children.
  • A case of sudden, unexpected death in a 2-year-old due to previously undiagnosed neuroblastoma is presented.
  • [MeSH-major] Adrenal Gland Neoplasms / complications. Adrenal Gland Neoplasms / diagnosis. Child Abuse / diagnosis. Death, Sudden / etiology. Neuroblastoma / complications. Neuroblastoma / diagnosis
  • [MeSH-minor] Autopsy. Cause of Death. Child, Preschool. Diagnosis, Differential. Forensic Pathology. Humans. Male

  • Genetic Alliance. consumer health - Neuroblastoma.
  • MedlinePlus Health Information. consumer health - Adrenal Gland Cancer.
  • MedlinePlus Health Information. consumer health - Child Abuse.
  • MedlinePlus Health Information. consumer health - Neuroblastoma.
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  • [Cites] Pediatr Clin North Am. 2002 Dec;49(6):1369-92, viii [12580370.001]
  • [Cites] J Pediatr. 1970 Aug;77(2):297-300 [5431211.001]
  • [Cites] Pediatr Dermatol. 2006 Jul-Aug;23(4):311-20 [16918624.001]
  • [Cites] AJR Am J Roentgenol. 1994 Mar;162(3):661-3 [8109518.001]
  • [Cites] Pediatr Dev Pathol. 2005 Jan-Feb;8(1):20-5 [15803214.001]
  • [Cites] Med Pediatr Oncol. 1982;10(1):21-6 [7062895.001]
  • [Cites] Pediatr Clin North Am. 2000 Aug;47(4):937-63 [10943267.001]
  • [Cites] J Forensic Sci. 2008 Nov;53(6):1430-3 [18808370.001]
  • [Cites] Hematol Oncol Clin North Am. 2010 Feb;24(1):65-86 [20113896.001]
  • [Cites] Am J Dis Child. 1982 Apr;136(4):370-1 [7072672.001]
  • [Cites] Pediatr Infect Dis J. 1992 Jul;11(7):595-6 [1528655.001]
  • [Cites] Acad Radiol. 1999 Jul;6(7):433-43 [10410169.001]
  • [Cites] Med Pediatr Oncol. 2000 May;34(5):343-7 [10797356.001]
  • [Cites] Am J Clin Pathol. 2005 Jun;123 Suppl:S119-24 [16100873.001]
  • [Cites] Am J Pediatr Hematol Oncol. 1979 Fall;1(3):201-5 [543514.001]
  • [Cites] Cancer. 1974 Feb;33(2):568-73 [4591273.001]
  • [Cites] Pediatr Emerg Care. 2008 Jan;24(1):37-8 [18212608.001]
  • (PMID = 20857235.001).
  • [ISSN] 1556-2891
  • [Journal-full-title] Forensic science, medicine, and pathology
  • [ISO-abbreviation] Forensic Sci Med Pathol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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9. Alavi S, Fahimzad A, Jadali F, Ghazizadeh F, Rashidi A: Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case. Case Rep Pediatr; 2013;2013:931703
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Concurrent adrenal neuroblastoma and kawasaki disease: a report of a rare case.
  • Neuroblastoma is the most common extracranial solid tumor in young children.
  • It mainly originates from primordial neural crest cells that generate the adrenal medulla and sympathetic ganglia.
  • A diagnosis of concurrent KD and neuroblastoma in a living child has been made in only one previous report.

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  • [Cites] Arch Pediatr Adolesc Med. 2002 Feb;156(2):162-5 [11814378.001]
  • [Cites] J Clin Endocrinol Metab. 2000 Feb;85(2):637-44 [10690869.001]
  • [Cites] Pediatrics. 1974 Sep;54(3):277-80 [4414762.001]
  • [Cites] Acta Pathol Jpn. 1986 Oct;36(10):1513-27 [3799188.001]
  • [Cites] Eur J Pediatr. 1991 Jan;150(3):179-82 [1904353.001]
  • [Cites] Am J Hematol. 1995 Dec;50(4):299-300 [7485107.001]
  • [Cites] Cancer. 1996 Aug 1;78(3):532-41 [8697401.001]
  • [Cites] J Pediatr Hematol Oncol. 1997 Sep-Oct;19(5):428-32 [9329464.001]
  • [Cites] J Clin Oncol. 2005 Sep 20;23(27):6459-65 [16116153.001]
  • [Cites] Am Fam Physician. 2006 Oct 1;74(7):1141-8 [17039750.001]
  • [Cites] Nat Genet. 2008 Jan;40(1):35-42 [18084290.001]
  • [Cites] Expert Rev Anti Infect Ther. 2010 Feb;8(2):197-203 [20109049.001]
  • [Cites] J Epidemiol. 2012;22(3):216-21 [22447211.001]
  • [Cites] Korean J Pediatr. 2012 Jun;55(6):202-5 [22745644.001]
  • [Cites] Best Pract Res Clin Endocrinol Metab. 2012 Aug;26(4):405-19 [22863384.001]
  • [Cites] Eur J Pediatr. 2002 Nov;161(11):631 [12532947.001]
  • (PMID = 23476867.001).
  • [ISSN] 2090-6803
  • [Journal-full-title] Case reports in pediatrics
  • [ISO-abbreviation] Case Rep Pediatr
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3580901
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10. Sano H, Fujimoto M, Okuno K, Ueyama J, Takano S, Hayashi K, Kanzaki S: Epstein-Barr virus-associated posttransplant lymphoproliferative disorder involving the central nervous system following autologous hematopoietic stem cell transplantation for neuroblastoma. Springerplus; 2014;3:582
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Epstein-Barr virus-associated posttransplant lymphoproliferative disorder involving the central nervous system following autologous hematopoietic stem cell transplantation for neuroblastoma.
  • INTRODUCTION: Posttransplant lymphoproliferative disorder (PTLD) is a serious complication following solid organ or hematopoietic stem cell transplantation (HSCT).
  • CASE DESCRIPTION: Herein, we report the first report of a patient with neuroblastoma that progressed to CNS-PTLD after autologous peripheral blood stem cell transplantation (auto-PBSCT).
  • A 27-month-old boy with stage IV neuroblastoma of the left adrenal gland received auto-PBSCT after intensive chemotherapy, tumor resection, and radiation of tumor bed and regional lymph node.
  • The histological diagnosis of the intracranial tumor was diffuse large B-cell lymphoma with latency type III Epstein-Barr virus infection.

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  • (PMID = 25332882.001).
  • [ISSN] 2193-1801
  • [Journal-full-title] SpringerPlus
  • [ISO-abbreviation] Springerplus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Other-IDs] NLM/ PMC4194306
  • [Keywords] NOTNLM ; Autologous hematopoietic stem cell transplantation / Central nervous system / Epstein-Barr virus / Neuroblastoma / Posttransplant lymphoproliferative disorder
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