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Items 1 to 10 of about 80790
1. Li Y, Yang Z, Li J: Shelf-life extension of Pacific white shrimp using algae extracts during refrigerated storage. J Sci Food Agric; 2017 Jan;97(1):291-298
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Shelf-life extension of Pacific white shrimp using algae extracts during refrigerated storage.
  • BACKGROUND: Shrimp is a low-fat, high-protein aquatic product, and is susceptible to spoilage during storage.
  • To establish an effective method for the quality control of Pacific white shrimp, the effects of polyphenols (PP) and polysaccharides (PS) from Porphyra yezoensis on the quality of Pacific white shrimp were assessed during refrigerated storage.
  • Pacific white shrimp samples were treated with 5 g L<sup>-1</sup> polyphenols, and 8 g L<sup>-1</sup> polysaccharides, then stored at 4 ± 1 °C for 8 days.
  • All samples were subjected to measurement of total viable count (TVC), pH, total volatile basic nitrogen (TVB-N), K-value, thiobarbituric acid (TBA), polyphenol oxidase (PPO) activity, and were also assessed by sensory evaluation.
  • RESULTS: The results showed that PP, PS, and the mixture of polyphenols and polysaccharides (PP+PS) could inhibit the increase of total volatile basic nitrogen (TVB-N), thiobarbituric acid (TBA) and K-value, and reduce total viable count (TVC) compared with the control group.
  • PP could also inhibit polyphenol oxidase (PPO) activity.
  • Sensory evaluation proved the efficacy of PP and PS by maintaining the overall quality of Pacific white shrimp during refrigerated storage.
  • Moreover, PP+PS could extend the shelf-life of shrimp by 3-4 days compared with the control group.
  • CONCLUSION: PP+PS could more effectively maintain quality and extend shelf-life during refrigerated storage.
  • © 2016 Society of Chemical Industry.
  • [MeSH-major] Food Preservation / methods. Penaeidae. Polyphenols / administration & dosage. Polysaccharides / administration & dosage. Porphyra / chemistry. Shellfish
  • [MeSH-minor] Animals. Catechol Oxidase / antagonists & inhibitors. Cold Temperature. Nitrogen / analysis. Quality Control. Thiobarbiturates / analysis. Time Factors. Volatilization

  • Hazardous Substances Data Bank. Nitrogen, Elemental .
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  • [Copyright] © 2016 Society of Chemical Industry.
  • (PMID = 27013186.001).
  • [ISSN] 1097-0010
  • [Journal-full-title] Journal of the science of food and agriculture
  • [ISO-abbreviation] J. Sci. Food Agric.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Polyphenols; 0 / Polysaccharides; 0 / Thiobarbiturates; EC 1.10.3.1 / Catechol Oxidase; M1YZW5SS7C / thiobarbituric acid; N762921K75 / Nitrogen
  • [Keywords] NOTNLM ; Pacific white shrimp / Porphyra yezoensis / polyphenols / polysaccharides / refrigerated storage
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2. Li Y, Hu X, Lin H, Yang Z: A framework for semisupervised feature generation and its applications in biomedical literature mining. IEEE/ACM Trans Comput Biol Bioinform; 2011 Mar-Apr;8(2):294-307
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A framework for semisupervised feature generation and its applications in biomedical literature mining.
  • Feature representation is essential to machine learning and text mining.
  • In this paper, we present a feature coupling generalization (FCG) framework for generating new features from unlabeled data.
  • It selects two special types of features, i.e., example-distinguishing features (EDFs) and class-distinguishing features (CDFs) from original feature set, and then generalizes EDFs into higher-level features based on their coupling degrees with CDFs in unlabeled data.
  • The advantage is: EDFs with extreme sparsity in labeled data can be enriched by their co-occurrences with CDFs in unlabeled data so that the performance of these low-frequency features can be greatly boosted and new information from unlabeled can be incorporated.
  • We apply this approach to three tasks in biomedical literature mining: gene named entity recognition (NER), protein-protein interaction extraction (PPIE), and text classification (TC) for gene ontology (GO) annotation.
  • New features are generated from over 20 GB unlabeled PubMed abstracts.
  • The experimental results on BioCreative 2, AIMED corpus, and TREC 2005 Genomics Track show that 1) FCG can utilize well the sparse features ignored by supervised learning.
  • 2) It improves the performance of supervised baselines by 7.8 percent, 5.0 percent, and 5.8 percent, respectively, in the tree tasks.
  • 3) Our methods achieve 89.1, 64.5 F-score, and 60.1 normalized utility on the three benchmark data sets.

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  • (PMID = 20876938.001).
  • [ISSN] 1557-9964
  • [Journal-full-title] IEEE/ACM transactions on computational biology and bioinformatics
  • [ISO-abbreviation] IEEE/ACM Trans Comput Biol Bioinform
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] United States
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3. Huang C, Han L, Yang Z, Liu X: Ultimate analysis and heating value prediction of straw by near infrared spectroscopy. Waste Manag; 2009 Jun;29(6):1793-7
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  • [Title] Ultimate analysis and heating value prediction of straw by near infrared spectroscopy.
  • Ultimate analysis and heating value determination are two of the most important routine analyses for exploiting agricultural wastes for energy conversion.
  • The use of near infrared spectroscopy (NIRS) was investigated as an alternative method to predict the carbon, hydrogen, and nitrogen content and the heating value of straw.
  • A total of 222 straw samples, collected from 24 provinces of China, were used for NIRS calibration and validation in this study.
  • The R(v)(2) and standard error of predictions in independent validation were, respectively, 0.97 and 0.37% for C, 0.77 and 0.17% for H, 0.87 and 0.10% for N and 0.96 and 181 J/g for heating value.
  • A multiple linear regression (MLR) model was also built to predict the heating value from the contents of C, H and N.
  • The MLR equation gave good prediction (standard error of prediction=224 J/g) when evaluated using the same validation set as the NIRS.
  • Therefore, rapid analysis of straw can be achieved through the constructed equations, saving analytical time and cost.
  • [MeSH-major] Energy-Generating Resources. Hot Temperature. Oryza. Spectroscopy, Near-Infrared. Triticum
  • [MeSH-minor] Linear Models

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  • (PMID = 19138837.001).
  • [ISSN] 0956-053X
  • [Journal-full-title] Waste management (New York, N.Y.)
  • [ISO-abbreviation] Waste Manag
  • [Language] eng
  • [Publication-type] Journal Article; Validation Studies
  • [Publication-country] United States
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4. Yang Z, Qu X, Yu CY: Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at the MHC class III region. Front Biosci; 2001 Aug 1;6:D927-35
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Features of the two gene pairs RD-SKI2W and DOM3Z-RP1 located between complement component genes factor B and C4 at the MHC class III region.
  • Located at the 30 kb genomic region between complement factor B and component C4 are four ubiquitously expressed genes RD, SKI2W, DOM3Z and RP1.
  • Besides RP1, the protein products of the other three genes each has highly conserved homologues or related proteins in lower eukaryotes, contains leucine zipper motifs for protein interaction, and plays important roles related to RNA metabolism.
  • RD is a subunit of the negative transcription elongation factor, critical for the regulation of gene expression.
  • It has an RNA recognition motif and 24 copies of Arg-Asp (RD) repeats.
  • Ski2w is a nucleolar and cytoplasmic protein that has a putative RNA helicase domain.
  • Fusion proteins of human Ski2w expressed in insect cells and bacteria have ATPase activity.
  • The cytoplasmic protein of human Ski2w is associated with the polysomes and probably the 40S subunit of ribosomes.
  • Ski2w is probably involved in the regulation of translation and RNA turnover.
  • Dom3z is a nuclear protein whose yeast homologue forms a complex with an exoribonuclease.
  • RP1 (or STK19) is a Ser/Thr nuclear protein kinase.
  • No homologues of RP1 in lower eukaryotes have been discovered.
  • Six polymorphic residues are present in human Ski2w and two in Dom3z.
  • The potential roles of Ski2w and Dom3z on the clearance of degraded nuclear and cytoplasmic RNA raised their possibilities as susceptibility genes of systemic lupus erythematosus that is a disease with flawed processes in the removal of apoptotic materials.
  • [MeSH-major] DNA Helicases / genetics. DNA-Binding Proteins / genetics. Eye Proteins. Major Histocompatibility Complex. Nuclear Proteins / genetics. Trans-Activators / genetics
  • [MeSH-minor] Amino Acid Sequence. Animals. Complement C4 / genetics. Complement Factor B / genetics. Humans. Lupus Erythematosus, Systemic / genetics. Mice. Molecular Sequence Data. Multigene Family. RNA / metabolism. Sequence Homology, Amino Acid. Transcription Factors. Transcriptional Elongation Factors

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  • (PMID = 11487501.001).
  • [ISSN] 1093-9946
  • [Journal-full-title] Frontiers in bioscience : a journal and virtual library
  • [ISO-abbreviation] Front. Biosci.
  • [Language] eng
  • [Grant] United States / NCRR NIH HHS / RR / 1P41 RR06009; United States / NIAMS NIH HHS / AR / R01 AR43969
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Complement C4; 0 / DNA-Binding Proteins; 0 / DOM3Z protein, human; 0 / Eye Proteins; 0 / Nuclear Proteins; 0 / RP1 protein, human; 0 / Rdbp protein, mouse; 0 / Trans-Activators; 0 / Transcription Factors; 0 / Transcriptional Elongation Factors; 0 / negative elongation factor; 63231-63-0 / RNA; EC 3.4.21.47 / Complement Factor B; EC 3.6.4.- / DNA Helicases; EC 5.99.- / SKIV2L protein, human
  • [Number-of-references] 49
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5. Li Y, Hu X, Lin H, Yang Z: Learning an enriched representation from unlabeled data for protein-protein interaction extraction. BMC Bioinformatics; 2010;11 Suppl 2:S7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Learning an enriched representation from unlabeled data for protein-protein interaction extraction.
  • BACKGROUND: Extracting protein-protein interactions from biomedical literature is an important task in biomedical text mining.
  • Supervised machine learning methods have been used with great success in this task but they tend to suffer from data sparseness because of their restriction to obtain knowledge from limited amount of labelled data.
  • In this work, we study the use of unlabeled biomedical texts to enhance the performance of supervised learning for this task.
  • We use feature coupling generalization (FCG) - a recently proposed semi-supervised learning strategy - to learn an enriched representation of local contexts in sentences from 47 million unlabeled examples and investigate the performance of the new features on AIMED corpus.
  • RESULTS: The new features generated by FCG achieve a 60.1 F-score and produce significant improvement over supervised baselines.
  • The experimental analysis shows that FCG can utilize well the sparse features which have little effect in supervised learning.
  • The new features perform better in non-linear classifiers than linear ones.
  • We combine the new features with local lexical features, obtaining an F-score of 63.5 on AIMED corpus, which is comparable with the current state-of-the-art results.
  • We also find that simple Boolean lexical features derived only from local contexts are able to achieve competitive results against most syntactic feature/kernel based methods.
  • CONCLUSIONS: FCG creates a lot of opportunities for designing new features, since a lot of sparse features ignored by supervised learning can be utilized well.
  • Interestingly, our results also demonstrate that the state-of-the art performance can be achieved without using any syntactic information in this task.
  • [MeSH-major] Artificial Intelligence. Computational Biology / methods. Data Mining / methods. Protein Interaction Mapping
  • [MeSH-minor] Algorithms. Chi-Square Distribution

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  • [Cites] Bioinformatics. 2004 Nov 22;20(17):3206-13 [15231534.001]
  • [Cites] Artif Intell Med. 2005 Feb;33(2):139-55 [15811782.001]
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  • (PMID = 20406505.001).
  • [ISSN] 1471-2105
  • [Journal-full-title] BMC bioinformatics
  • [ISO-abbreviation] BMC Bioinformatics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC3166043
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6. Chen L, Yang L, Yang Z, Dai Z: [Magnetic resonance angiography in assessing changes of pre-and post-disconnective portal system in patients with portal hypertension]. Zhonghua Wai Ke Za Zhi; 2000 Feb;38(2):92-4
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  • [Title] [Magnetic resonance angiography in assessing changes of pre-and post-disconnective portal system in patients with portal hypertension].
  • OBJECTIVE: To evaluate the role of magnetic resonance angiography (MRA) in assessing the portal system changes in patients with portal hypertension after pericardial devascularization and splenectomy.
  • METHODS: The portal diameter, blood velocity and flow, collateral circulation, variceal vein and other portal parameters of 15 patients with portal hypertension receiving pericardial devascularization and splenectomy and splenectomy were comparatively evaluated with Siemens 1.5 T MRI 1 week before operation and 2 weeks after operation.
  • RESULTS: The portal diameters decreased after operation, with the disappearance or alleviation of esophageal and fundal variceal veins.
  • In 15 patients, 9 showed.
  • The blood velocity and flow of the portal veins were lower postoperatively. than those preoperatively; In 15 patients, 9 showed increased gastric imaging intensity after operation.
  • CONCLUSIONS: MRA can provide high quality and concrete 3-dimensional information about the portal system and hemodynamics of portal hypertensive patients.
  • It is an important non-invasive way in evaluating the effects of operations and long-term follow-up.
  • Postoperative gastric venous congestion possibly causes increased portal hypertensive gastropathy after disconnection.
  • [MeSH-major] Hypertension, Portal / pathology. Magnetic Resonance Angiography. Portal System / pathology
  • [MeSH-minor] Blood Flow Velocity. Female. Hemodynamics. Humans. Male. Middle Aged. Regional Blood Flow. Splenectomy

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  • (PMID = 11831996.001).
  • [ISSN] 0529-5815
  • [Journal-full-title] Zhonghua wai ke za zhi [Chinese journal of surgery]
  • [ISO-abbreviation] Zhonghua Wai Ke Za Zhi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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7. Gan M, Zuo H, Yang Z, Jiang Y: [The method of time series modeling and its application in the spectral analysis of lubricating oil]. Guang Pu Xue Yu Guang Pu Fen Xi; 2000 Feb;20(1):64-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [The method of time series modeling and its application in the spectral analysis of lubricating oil].
  • In this paper, we discuss the applications of time series modeling method in the analysis of lubricating oil of mechanical equipment.
  • We obtained satisfactory results by applying AR model to perform time series modeling and forecasting analysis to the collected spectral analysis data of the air engine.
  • So we have built a practical method for state monitoring and trouble forecasting of mechanical equipment.

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  • (PMID = 12953452.001).
  • [ISSN] 1000-0593
  • [Journal-full-title] Guang pu xue yu guang pu fen xi = Guang pu
  • [ISO-abbreviation] Guang Pu Xue Yu Guang Pu Fen Xi
  • [Language] chi
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] China
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8. Zhao X, Yang Z, Qian M, Zhu X: Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub. Biochem Biophys Res Commun; 2001 Jan 19;280(2):513-7
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  • [Title] Interactions among subunits of human Arp2/3 complex: p20-Arc as the hub.
  • The Arp2/3 complex is critical for nucleation and crosslinking of actin filaments.
  • To gain insight into its subunit topology and assembly pathway, we systematically examined interactions among subunits of human Arp2/3 complex by yeast two-hybrid assays.
  • It was shown that p20-Arc was able to interact with p21-Arc, p34-Arc, and p16-Arc, respectively.
  • In contrast, p41-Arc only interacted with p20-Arc/p16-Arc heterodimer.
  • In addition, we found that structural integrity was important for association between p20-Arc and p21-Arc, while the N-terminal half of p34-Arc was dispensable for its binding to p20-Arc.
  • Our data suggest a key role of p20-Arc and a multistep pathway for the complex formation.
  • [MeSH-major] Actins / metabolism. Cytoskeletal Proteins. Microfilament Proteins / chemistry. Microfilament Proteins / metabolism
  • [MeSH-minor] Actin-Related Protein 2. Actin-Related Protein 3. Dimerization. Humans. Macromolecular Substances. Molecular Weight. Protein Binding. Protein Subunits. Two-Hybrid System Techniques

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  • [Copyright] Copyright 2001 Academic Press.
  • (PMID = 11162547.001).
  • [ISSN] 0006-291X
  • [Journal-full-title] Biochemical and biophysical research communications
  • [ISO-abbreviation] Biochem. Biophys. Res. Commun.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / ACTR2 protein, human; 0 / ACTR3 protein, human; 0 / Actin-Related Protein 2; 0 / Actin-Related Protein 3; 0 / Actins; 0 / Cytoskeletal Proteins; 0 / Macromolecular Substances; 0 / Microfilament Proteins; 0 / Protein Subunits
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9. Zhong L, Li W, Yang Z, Chen L, Li Y, Qing K, Weigel-Kelley KA, Yoder MC, Shou W, Srivastava A: Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo. Gene Ther; 2004 Jul;11(14):1165-9
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  • [Title] Improved transduction of primary murine hepatocytes by recombinant adeno-associated virus 2 vectors in vivo.
  • Adeno-associated virus 2 (AAV) vectors are currently in use in Phase I/II clinical trials for gene therapy of cystic fibrosis and hemophilia B.
  • Although 100% of murine hepatocytes can be targeted by AAV vectors, the transgene expression is limited to approximately 5% of hepatocytes.
  • Since the viral genome is a single-stranded DNA, and single strands of both polarities are encapsidated with equal frequency, it has been suggested that failure to undergo DNA strand-annealing accounts for the lack of efficient transgene expression.
  • We and others, on the other hand, have proposed that failure to undergo viral second-strand DNA synthesis attributes to the observed low efficiency of transgene expression.
  • We have previously documented that a cellular protein, designated FKBP52, when present in phosphorylated forms, inhibits the viral second-strand DNA synthesis, and consequently, limits transgene expression in nonhepatic cells, whereas unphosphorylated forms of FKBP52 have no effect.
  • To further evaluate whether phosphorylated FKBP52 is also involved in regulating AAV-mediated transgene expression in murine hepatocytes, we generated transgenic mice overexpressing the cellular T-cell protein tyrosine phosphatase (TC-PTP) protein, known to catalyze dephosphorylation of FKBP52, as well as mice deficient in FKBP52.
  • We demonstrate here that dephosphorylation of FKBP52 in TC-PTP transgenic (TC-PTP-TG) mice, and removal of FKBP52 in FKBP52-knockout (FKBP52-KO) mice results in efficient transduction of murine hepatocytes following tail-vein injection of recombinant AAV vectors.
  • We also document efficient viral second-strand DNA synthesis in hepatocytes from both TC-PTP-TG and FKBP52-KO mice.
  • Thus, our data strongly support the contention that the viral second-strand DNA synthesis, rather than DNA strand-annealing, is the rate-limiting step in the efficient transduction of hepatocytes, which should have implications in the optimal use of recombinant AAV vectors in human gene therapy.
  • [MeSH-major] Dependovirus / genetics. Genetic Therapy / methods. Genetic Vectors / administration & dosage. Hepatocytes / metabolism. Transduction, Genetic / methods
  • [MeSH-minor] Animals. DNA / biosynthesis. Gene Expression Regulation. Mice. Mice, Knockout. Mice, Transgenic. Protein Tyrosine Phosphatase, Non-Receptor Type 2. Protein Tyrosine Phosphatases / genetics. Protein Tyrosine Phosphatases / metabolism. Tacrolimus Binding Proteins / genetics. Tacrolimus Binding Proteins / metabolism

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  • (PMID = 15164097.001).
  • [ISSN] 0969-7128
  • [Journal-full-title] Gene therapy
  • [ISO-abbreviation] Gene Ther.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R01 HL-65570; United States / NIBIB NIH HHS / EB / R01EB-002073; United States / NHLBI NIH HHS / HL / R01HL-70259; United States / NHLBI NIH HHS / HL / T32HL-07910
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] England
  • [Chemical-registry-number] 9007-49-2 / DNA; EC 3.1.3.48 / PTPN2 protein, human; EC 3.1.3.48 / Protein Tyrosine Phosphatase, Non-Receptor Type 2; EC 3.1.3.48 / Protein Tyrosine Phosphatases; EC 3.1.3.48 / Ptpn2 protein, mouse; EC 5.2.1.- / Tacrolimus Binding Proteins; EC 5.2.1.- / tacrolimus binding protein 4
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