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Items 1 to 10 of about 830
1. Wilczynski NL, Walker CJ, McKibbon KA, Haynes RB: Preliminary assessment of the effect of more informative (structured) abstracts on citation retrieval from MEDLINE. Medinfo; 1995;8 Pt 2:1457-61
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Preliminary assessment of the effect of more informative (structured) abstracts on citation retrieval from MEDLINE.
  • OBJECTIVE: To compare the recall and precision of citation retrieval from MEDLINE when searching in journals containing traditional abstracts with journals containing abstracts prepared according to the guidelines of more informative abstracts (MIAs) for clinical journal articles.
  • DESIGN: Analytic survey of operating characteristics of MeSH terms and textwords selected to detect studies meeting basic methodological criteria for direct clinical use in general adult medicine in priority journals with and without MIAs.
  • MEASURES: The sensitivity, specificity, and precision of search terms were determined by comparison with a manual review of all articles (the gold standard) in 10 internal and general medicine journals for 1986 and 1991.
  • The performance of each search term was compared before and after the implementation of MIAs and in two journal sets with and without MIAs in 1991.
  • RESULTS: The sensitivity of some terms increased with the use of MIAs and also increased by the same amount in journals with usual abstracts in 1991 compared to 1986.
  • The use of MIAs had the greatest impact in the areas of etiology and prognosis.
  • Many MeSH and textwords had comparable performance before and after the implementation of MIAs and between journals with and without MIAs in 1991.
  • CONCLUSIONS: More informative abstracts improved the retrieval properties of some, but not all, textwords and medical subject headings.
  • Further work may be needed to enhance the effects of MIAs on bibliographic retrieval.
  • [MeSH-major] Abstracting and Indexing as Topic / methods. Information Storage and Retrieval. MEDLINE
  • [MeSH-minor] Natural Language Processing. Periodicals as Topic. Subject Headings

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  • (PMID = 8591474.001).
  • [ISSN] 1569-6332
  • [Journal-full-title] Medinfo. MEDINFO
  • [ISO-abbreviation] Medinfo
  • [Language] eng
  • [Publication-type] Comparative Study; Journal Article
  • [Publication-country] CANADA
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2. Wilczynski NL, Walker CJ, McKibbon KA, Haynes RB: Assessment of methodologic search filters in MEDLINE. Proc Annu Symp Comput Appl Med Care; 1993;:601-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Assessment of methodologic search filters in MEDLINE.
  • OBJECTIVE: To determine the retrieval characteristics of methodologic textwords and MeSH terms in MEDLINE for identifying methodologically sound studies on the etiology, prognosis, diagnosis, and prevention and treatment of disorders in general adult medicine.
  • DESIGN: Comparison of methodologic search terms and phrases for the retrieval of citations in MEDLINE with a manual hand search of the literature (the gold standard) for 10 internal and general medicine journals for 1986 and 1991.
  • MEASURES: Sensitivity (proportion of methodologically sound and correct topic studies retrieved) and specificity (proportion of unsound or wrong topic articles not retrieved) of the search strategies.
  • RESULTS: The individual terms yielding the best sensitivity for 1991 by purpose category were: risk (tw) for etiology; exp cohort studies for prognosis; sensitivity (tw) for diagnosis; and clinical trial (pt) for treatment.
  • The corresponding terms for 1986 were: risk (tw) for etiology; prognosis: (tw) for prognosis; sensitivity (tw) for diagnosis; and random: (tw) for treatment.
  • CONCLUSIONS: The performance of methodologic MeSH terms and textwords varied greatly in MEDLINE and changed from 1986 to 1991.
  • More complex search strategies may be required to optimize retrieval.

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  • [Cites] Control Clin Trials. 1985 Dec;6(4):271-9 [3907971.001]
  • [Cites] Ann Intern Med. 1986 Nov;105(5):810-6 [3532898.001]
  • [Cites] Control Clin Trials. 1985 Dec;6(4):306-17 [3907973.001]
  • [Cites] Pediatrics. 1989 Apr;83(4):543-6 [2648304.001]
  • (PMID = 8130545.001).
  • [ISSN] 0195-4210
  • [Journal-full-title] Proceedings. Symposium on Computer Applications in Medical Care
  • [ISO-abbreviation] Proc Annu Symp Comput Appl Med Care
  • [Language] ENG
  • [Grant] United States / NLM NIH HHS / LM / R01 LM04696-03
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC2850647
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3. Fatti G, Shaikh N, Eley B, Grimwood A: Effectiveness of community-based support for pregnant women living with HIV: a cohort study in South Africa. AIDS Care; 2016;28 Suppl 1:114-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effectiveness of community-based support for pregnant women living with HIV: a cohort study in South Africa.
  • Antiretroviral treatment (ART) initiation in HIV-infected pregnant women in sub-Saharan Africa (SSA) remains inadequate, and there is a severe shortage of professional healthcare workers in the region.
  • The effectiveness of community support programmes for HIV-infected pregnant women and their infants in SSA is unclear.
  • This study compared initiation of maternal antiretrovirals and infant outcomes amongst HIV-infected pregnant women and their infants who received and did not receive community-based support (CBS) in a high HIV-prevalence setting in South Africa.
  • A cohort study, including HIV-infected pregnant women and their infants, was conducted at three sentinel surveillance facilities between January 2009 and June 2012, utilising enhanced routine clinical data.
  • Through home visits, CBS workers encouraged uptake of interventions in the ART cascade, provided HIV-related education, ART initiation counselling and psychosocial support.
  • Outcomes were compared using Kaplan-Meier analyses and multivariable Cox and log-binomial regression.
  • Amongst 1105 mother-infant pairs included, 264 (23.9%) received CBS.
  • Amongst women eligible to start ART antenatally, women who received CBS had a reduced risk of not initiating antenatal ART, 5.4% vs. 30.3%; adjusted risk ratio (aRR) = 0.18 (95% CI: 0.08-0.44; P < .0001).
  • Women who received CBS initiated antenatal ART with less delay after the first antenatal visit, median 26 days vs. 39 days; adjusted hazard ratio (aHR) = 1.57 (95% CI: 1.15-2.14; P = .004).
  • Amongst women who initiated antenatal zidovudine (ZDV) to prevent vertical transmission, women who received CBS initiated ZDV with less delay, aHR = 1.52 (95% CI: 1.18-2.01; P = .001).
  • Women who received CBS had a lower risk of stillbirth, 1.5% vs. 5.4%; aRR = 0.24 (95% CI: 0.07-1.00; P = .050).
  • Pregnant women living with HIV who received CBS had improved antenatal triple ART initiation in eligible women, women initiated ART and ZDV with shorter delays, and had a lower risk of stillbirth.
  • CBS is an intervention that shows promise in improving maternal and infant health in high HIV-prevalence settings.
  • [MeSH-major] Anti-HIV Agents / therapeutic use. HIV Infections / drug therapy. Infectious Disease Transmission, Vertical / prevention & control. Pregnancy Complications, Infectious / drug therapy. Pregnant Women / psychology
  • [MeSH-minor] Adult. Cohort Studies. Community Health Services. Community-Based Participatory Research. Counseling. Female. Humans. Infant. Pregnancy. Pregnancy Outcome. Prenatal Care. Prevalence. South Africa / epidemiology. Treatment Outcome. Urban Population. Young Adult


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4. Logan AG, Milne BJ, Achber C, Campbell WA, Haynes RB: A comparison of community and occupationally provided antihypertensive care. J Occup Med; 1982 Nov;24(11):901-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A comparison of community and occupationally provided antihypertensive care.
  • [MeSH-major] Antihypertensive Agents / therapeutic use. Hypertension / drug therapy. Occupational Medicine
  • [MeSH-minor] Clinical Trials as Topic. Community Health Services. Consumer Behavior. Humans. Ontario. Outcome and Process Assessment (Health Care). Patient Compliance. Random Allocation

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  • (PMID = 6757394.001).
  • [ISSN] 0096-1736
  • [Journal-full-title] Journal of occupational medicine. : official publication of the Industrial Medical Association
  • [ISO-abbreviation] J Occup Med
  • [Language] eng
  • [Publication-type] Clinical Trial; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antihypertensive Agents
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5. Khan MH, Baldo O, Koenig P, Shaikh N: Use of prophylactic antibiotics for intra-vesicle Botox® injection. Neurourol Urodyn; 2017 Mar;36(3):828
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Use of prophylactic antibiotics for intra-vesicle Botox® injection.
  • AIM: Botox injection in bladder wall is increasingly used in urology for over active bladder and neurogenic bladder.
  • Aim of this audit is to assess the incidence of UTI after procedure and need for routine use of pre and post procedure antibiotics.
  • METHOD: It was case notes and lab results based retrospective study of all the patients attended for intra-vesicle Botox injection.
  • RESULTS: Rate of UTI's were lower in the group who received antibiotics pre and post operatively as compared to those who did not.
  • CONCLUSION: Routine antibiotics use lowers the risk of UTI's in patients receiving intra-vesicle botox. Neurourol. Urodynam.
  • 36:828-828, 2017.
  • © 2016 Wiley Periodicals, Inc.

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  • [Copyright] © 2016 Wiley Periodicals, Inc.
  • (PMID = 27177011.001).
  • [ISSN] 1520-6777
  • [Journal-full-title] Neurourology and urodynamics
  • [ISO-abbreviation] Neurourol. Urodyn.
  • [Language] eng
  • [Publication-type] Letter
  • [Publication-country] United States
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6. Shaikh N, Ummunissa F, Abdel Sattar M: Traumatic mitral valve and pericardial injury. Case Rep Crit Care; 2013;2013:385670
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Traumatic mitral valve and pericardial injury.
  • Cardiac injury after blunt trauma is common but underreported.
  • Common cardiac trauma after the blunt chest injury (BCI) is cardiac contusion; it is very rare to have cardiac valve injury.
  • The mitral valve injury during chest trauma occurs when extreme pressure is applied at early systole during the isovolumic contraction between the closure of the mitral valve and the opening of the aortic valve.
  • Traumatic mitral valve injury can involve valve leaflet, chordae tendineae, or papillary muscles.
  • For the diagnosis of mitral valve injury, a high index of suspicion is required, as in polytrauma patients, other obvious severe injuries will divert the attention of the treating physician.
  • Clinical picture of patients with mitral valve injury may vary from none to cardiogenic shock.
  • The echocardiogram is the main diagnostic modality of mitral valve injuries.
  • Patient's clinical condition will dictate the timing and type of surgery or medical therapy.
  • We report a case of mitral valve and pericardial injury in a polytrauma patient, successfully treated in our intensive care unit.

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  • (PMID = 24829821.001).
  • [ISSN] 2090-6420
  • [Journal-full-title] Case reports in critical care
  • [ISO-abbreviation] Case Rep Crit Care
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4010058
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8. Wright D, Young A, Iserman E, Maeso R, Turner S, Haynes RB, Milne R: The clinical relevance and newsworthiness of NIHR HTA-funded research: a cohort study. BMJ Open; 2014;4(5):e004556
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] The clinical relevance and newsworthiness of NIHR HTA-funded research: a cohort study.
  • OBJECTIVE: To assess the clinical relevance and newsworthiness of the UK National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme funded reports.
  • STUDY DESIGN: Retrospective cohort study.
  • SETTING: The cohort included 311 NIHR HTA Programme funded reports publishing in HTA in the period 1 January 2007-31 December 2012.
  • The McMaster Online Rating of Evidence (MORE) system independently identified the clinical relevance and newsworthiness of NIHR HTA publications and non-NIHR HTA publications.
  • The MORE system involves over 4000 physicians rating publications on a scale of relevance (the extent to which articles are relevant to practice) and a scale of newsworthiness (the extent to which articles contain news or something clinicians are unlikely to know).
  • MAIN OUTCOME MEASURES: The proportion of reports published in HTA meeting MORE inclusion criteria and mean average relevance and newsworthiness ratings were calculated and compared with publications from the same studies publishing outside HTA and non-NIHR HTA funded publications.
  • RESULTS: 286/311 (92.0%) of NIHR HTA reports were assessed by MORE, of which 192 (67.1%) passed MORE criteria.
  • The average clinical relevance rating for NIHR HTA reports was 5.48, statistically higher than the 5.32 rating for non-NIHR HTA publications (mean difference=0.16, 95% CI 0.04 to 0.29, p=0.01).
  • Average newsworthiness ratings were similar between NIHR HTA reports and non-NIHR HTA publications (4.75 and 4.70, respectively; mean difference=0.05, 95% CI -0.18 to 0.07, p=0.402).
  • NIHR HTA-funded original research reports were statistically higher for newsworthiness than reviews (5.05 compared with 4.64) (mean difference=0.41, 95% CI 0.18 to 0.64, p=0.001).
  • CONCLUSIONS: Funding research of clinical relevance is important in maximising the value of research investment.
  • The NIHR HTA Programme is successful in funding projects that generate outputs of clinical relevance.
  • [MeSH-major] Biomedical Research. Technology Assessment, Biomedical
  • [MeSH-minor] Cohort Studies. Government Agencies. Great Britain. Program Evaluation. Publishing. Retrospective Studies

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  • [Cites] Lancet. 2000 Jun 10;355(9220):2037-40 [10885355.001]
  • [Cites] BMC Med. 2004 Sep 6;2:33 [15350200.001]
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  • (PMID = 24812191.001).
  • [ISSN] 2044-6055
  • [Journal-full-title] BMJ open
  • [ISO-abbreviation] BMJ Open
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4024580
  • [Keywords] NOTNLM ; Statistics & Research Methods
  • [General-notes] NLM/ Original DateCompleted: 20140509
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9. Shaikh N, Morone NE, Bost JE, Farrell MH: Prevalence of urinary tract infection in childhood: a meta-analysis. Pediatr Infect Dis J; 2008 Apr;27(4):302-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prevalence of urinary tract infection in childhood: a meta-analysis.
  • BACKGROUND: Knowledge of baseline risk of urinary tract infection can help clinicians make informed diagnostic and therapeutic decisions.
  • We conducted a meta-analysis to determine the pooled prevalence of urinary tract infection (UTI) in children by age, gender, race, and circumcision status.
  • METHODS: MEDLINE and EMBASE databases were searched for articles about pediatric urinary tract infection.
  • Search terms included urinary tract infection, cystitis, pyelonephritis, prevalence and incidence.
  • We included articles in our review if they contained data on the prevalence of UTI in children 0-19 years of age presenting with symptoms of UTI.
  • Of the 51 articles with data on UTI prevalence, 18 met all inclusion criteria.
  • Two evaluators independently reviewed, rated, and abstracted data from each article.
  • RESULTS: Among infants presenting with fever, the overall prevalence (and 95% confidence interval) of UTI was 7.0% (CI: 5.5-8.4).
  • The pooled prevalence rates of febrile UTIs in females aged 0-3 months, 3-6 months, 6-12 months, and >12 months was 7.5%, 5.7%, 8.3%, and 2.1% respectively.
  • Among febrile male infants less than 3 months of age, 2.4% (CI: 1.4-3.5) of circumcised males and 20.1% (CI: 16.8-23.4) of uncircumcised males had a UTI.
  • For the 4 studies that reported UTI prevalence by race, UTI rates were higher among white infants 8.0% (CI: 5.1-11.0) than among black infants 4.7% (CI: 2.1-7.3).
  • Among older children (<19 years) with urinary symptoms, the pooled prevalence of UTI (both febrile and afebrile) was 7.8% (CI: 6.6-8.9).
  • CONCLUSIONS: Prevalence rates of UTI varied by age, gender, race, and circumcision status.
  • Uncircumcised male infants less than 3 months of age and females less than 12 months of age had the highest baseline prevalence of UTI.
  • Prevalence estimates can help clinicians make informed decisions regarding diagnostic testing in children presenting with signs and symptoms of urinary tract infection.
  • [MeSH-major] Urinary Tract Infections / epidemiology
  • [MeSH-minor] Adolescent. Age Factors. Child. Child, Preschool. Circumcision, Male. Ethnic Groups. Female. Humans. Infant. Infant, Newborn. Male. Prevalence. Risk Factors. Sex Factors


10. Spitzer N, Shaikh N, Strickland L, Ho S: Recurrent Squamous Cell Carcinoma of the Eyelid Presenting as Trigeminal Neuralgia. Cureus; 2016 Dec 16;8(12):e932
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recurrent Squamous Cell Carcinoma of the Eyelid Presenting as Trigeminal Neuralgia.
  • This paper describes two patients with squamous cell carcinoma (SCC) of the periocular and periorbital skin who presented with trigeminal neuralgia.
  • Both patients had previous cutaneous SCC of the scalp treated successfully with surgical resection but later presented with neuro-ophthalmic findings suggesting perineural invasion (PNI) of SCC.
  • PNI of SCC in the periocular skin or orbit can lead to devastating effects if malignant cells seed into the orbit and adjacent cranial nerves as our two patients developed an orbital apex syndrome.
  • Patients with a history of SCC of the scalp and forehead who later develop neuro-ophthalmological deficits or patients with persistent ocular symptoms should, in particular, be followed with a low threshold for cutaneous SCC or PNI of recurrent disease.
  • SCC metastasizing into the periocular tissues and orbit by neural invasion is rare and carries a poor prognosis.
  • The urgency for a prompt diagnosis and evaluation by a multidisciplinary team is warranted to prevent untoward outcomes of this skin cancer.

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  • (PMID = 28097083.001).
  • [ISSN] 2168-8184
  • [Journal-full-title] Cureus
  • [ISO-abbreviation] Cureus
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; orbital apex syndrome / squamous cell carcinoma / trigeminal neuralgia
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