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Items 1 to 10 of about 2835
1. Pham TA, Kim JJ, Kim K: Optimization of Solid-State Fermentation for Improved Conidia Production of Beauveria bassiana as a Mycoinsecticide. Mycobiology; 2010 Jun;38(2):137-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimization of Solid-State Fermentation for Improved Conidia Production of Beauveria bassiana as a Mycoinsecticide.
  • The production of conidia of entomopathogenic Beauveria bassiana by solid-state fermentation was studied for the development of a biocontrol agent against aphid Myzus persicae.
  • The optimal conditions for conidia production on polished white rice were 40% moisture content, 25℃ culture temperature, 2-day-old seeding culture grown in 3% corn meal, 2% rice bran, 2% corn steep powder medium, initial conidia concentration of 10(7) conidia/g in the wet rice, 10% inoculum size, and use of a polyethylene bag as a container.
  • The polyethylene bag containing inoculated rice was hand-shaken every 12 hr during fermentation.
  • Using optimal conditions, the maximum conidia production obtained was 4.05 g conidia/100 g dry rice after 14 days of cultivation, a rate 2.83 times higher than conidia yield of pre-optimization.

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  • (PMID = 23956642.001).
  • [ISSN] 1229-8093
  • [Journal-full-title] Mycobiology
  • [ISO-abbreviation] Mycobiology
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC3741565
  • [Keywords] NOTNLM ; Beauveria bassiana / Conidia production / Optimal culture conditions / Solid-state fermentation
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2. Cai H, Green PA, Kim JJ: Estimating the legibility of a single letter E viewed at different display angles. Appl Ergon; 2013 Jul;44(4):575-87
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Estimating the legibility of a single letter E viewed at different display angles.
  • Text is often viewed not perpendicularly to its display.
  • With nine assumptions, this study developed a new equation for estimating the legibility of a single letter E viewed at different display angles.
  • This equation examines viewing distance, text height, strokewidth, Snellen acuity, background luminance, luminance contrast, and incident angle.
  • This equation was derived from the existing Howett's equation based on a constant-solid-angle hypothesis tested in a lighting laboratory by reading letter 'E's using 20 young human subjects.
  • The hypothesis holds when the incident angle 0° ≤ ξ ≤ 65.7°, but fails when 65.7° < ξ ≤ 82.8° (the maximum angle tested).
  • Another ambient-light hypothesis was also tested in the same laboratory using 20 young subjects to verify the negligible influence (less than 9%) of ambient light on legibility of text.
  • The new equation was accordingly improved to help ergonomists and other professionals create and maintain legible displays.
  • [MeSH-major] Reading. Vision, Ocular / physiology. Visual Acuity / physiology
  • [MeSH-minor] Color. Humans. Lighting

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  • [Copyright] Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.
  • (PMID = 23254109.001).
  • [ISSN] 1872-9126
  • [Journal-full-title] Applied ergonomics
  • [ISO-abbreviation] Appl Ergon
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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3. Kim JJ, Hou L, Huang NF: Vascularization of three-dimensional engineered tissues for regenerative medicine applications. Acta Biomater; 2016 Sep 01;41:17-26
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  • [Title] Vascularization of three-dimensional engineered tissues for regenerative medicine applications.
  • Engineering of three-dimensional (3D) tissues is a promising approach for restoring diseased or dysfunctional myocardium with a functional replacement.
  • However, a major bottleneck in this field is the lack of efficient vascularization strategies, because tissue constructs produced in vitro require a constant flow of oxygen and nutrients to maintain viability and functionality.
  • Compared to angiogenic cell therapy and growth factor treatment, bioengineering approaches such as spatial micropatterning, integration of sacrificial materials, tissue decellularization, and 3D bioprinting enable the generation of more precisely controllable neovessel formation.
  • In this review, we summarize the state-of-the-art approaches to develop 3D tissue engineered constructs with vasculature, and demonstrate how some of these techniques have been applied towards regenerative medicine for treatment of heart failure.
  • STATEMENT OF SIGNIFICANCE: Tissue engineering is a promising approach to replace or restore dysfunctional tissues/organs, but a major bottleneck in realizing its potential is the challenge of creating scalable 3D tissues.
  • Since most 3D engineered tissues require a constant supply of nutrients, it is necessary to integrate functional vasculature within the tissues in order to facilitate the transport of nutrients.
  • To address these needs, researchers are employing biomaterial engineering and design strategies to foster vessel formation within 3D tissues.
  • This review highlights the state-of-the-art bioengineering tools and technologies to create vascularized 3D tissues for clinical applications in regenerative medicine, highlighting the application of these technologies to engineer vascularized cardiac patches for treatment of heart failure.
  • [MeSH-major] Neovascularization, Physiologic. Regenerative Medicine / methods. Tissue Engineering / methods
  • [MeSH-minor] Animals. Biocompatible Materials / pharmacology. Humans. Printing, Three-Dimensional

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  • [Copyright] Published by Elsevier Ltd.
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  • (PMID = 27262741.001).
  • [ISSN] 1878-7568
  • [Journal-full-title] Acta biomaterialia
  • [ISO-abbreviation] Acta Biomater
  • [Language] eng
  • [Grant] United States / NIBIB NIH HHS / EB / R21 EB020235; United States / NHLBI NIH HHS / HL / K99 HL098688; United States / NHLBI NIH HHS / HL / R01 HL127113; United States / NHLBI NIH HHS / HL / R00 HL098688; United States / BLRD VA / BX / I01 BX002310
  • [Publication-type] Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biocompatible Materials
  • [Other-IDs] NLM/ NIHMS795409 [Available on 09/01/17]; NLM/ PMC4969172 [Available on 09/01/17]
  • [Keywords] NOTNLM ; 3D bioprinting / Biomaterials / Cardiac engineering / Endothelial cell / Extracellular matrix / Tissue engineering / Vascularization
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4. Kim JJ, Rison RA, Fanselow MS: Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear. Behav Neurosci; 1993 Dec;107(6):1093-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Effects of amygdala, hippocampus, and periaqueductal gray lesions on short- and long-term contextual fear.
  • The effects of amygdala, hippocampus, and periaqueductal gray (PAG) lesions on contextual fear conditioning in rats were examined.
  • Freezing behavior served as the measure of conditioning.
  • Unlesioned control animals showed reliable conditional freezing in the testing chamber when observed both immediately and 24 hr after footshocks.
  • In contrast, rats with amygdala or ventral PAG lesions exhibited a significant attenuation in freezing both immediately and 24 hr after the shocks.
  • Dorsal PAG lesions had no effect on freezing at either time.
  • Animals with hippocampal lesions displayed robust freezing behavior immediately following the shock, even though they showed a marked deficit in freezing 24 hr after the shock.
  • These results indicate that there are anatomically dissociable short- and long-term conditional fear states.
  • [MeSH-major] Amygdala / physiology. Conditioning, Classical / physiology. Fear / physiology. Hippocampus / physiology. Long-Term Potentiation / physiology. Mental Recall / physiology. Periaqueductal Gray / physiology. Retention (Psychology) / physiology
  • [MeSH-minor] Animals. Association Learning / physiology. Brain Mapping. Electroshock. Female. Neural Pathways / physiology. Neuronal Plasticity / physiology. Rats. Receptors, N-Methyl-D-Aspartate / physiology

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  • (PMID = 8136063.001).
  • [ISSN] 0735-7044
  • [Journal-full-title] Behavioral neuroscience
  • [ISO-abbreviation] Behav. Neurosci.
  • [Language] eng
  • [Grant] United States / NIMH NIH HHS / MH / MH39786
  • [Publication-type] Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Receptors, N-Methyl-D-Aspartate
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5. Kim JJ, Lee SY, Ha K: The effects of exercise using PNF in patients with a supraspinatus muscle tear. J Phys Ther Sci; 2015 Aug;27(8):2443-6
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  • [Title] The effects of exercise using PNF in patients with a supraspinatus muscle tear.
  • [Purpose] The aim of this study was to examine the effects of proprioceptive neuromuscular facilitation techniques and simple exercise on subjective pain reduction and blood flow velocity in supraspinatus tear patients and to evaluate muscle recovery.
  • [Subjects and Methods] The 20 subjects of this study were diagnosed with supraspinatus tears by MRI.
  • The subjects have performed PNF techniques and Simple exercise for 12 weeks.
  • [Results] After 12 weeks of proprioceptive neuromuscular facilitation techniques and simple exercise, the blood flow velocity, Visual Analogue Scale, and disabilities of the arm, shoulder, and hand score showed statistically significant difference.
  • Also, the difference between the proprioceptive neuromuscular facilitation techniques and simple exercise was statistically significant.
  • [Conclusion] In conclusion, 12 weeks of proprioceptive neuromuscular facilitation treatment and simple exercise therapy had no effect on pain reduction in patients with supraspinatus tear, but in terms of functionality, the proprioceptive neuromuscular facilitation treatment was effective.

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  • (PMID = 26356542.001).
  • [ISSN] 0915-5287
  • [Journal-full-title] Journal of physical therapy science
  • [ISO-abbreviation] J Phys Ther Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Other-IDs] NLM/ PMC4563286
  • [Keywords] NOTNLM ; DASH / PNF / Supraspinatus tear
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6. Han X, Kim JJ, Kwoh CK: Active learning for ontological event extraction incorporating named entity recognition and unknown word handling. J Biomed Semantics; 2016;7:22
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  • [Title] Active learning for ontological event extraction incorporating named entity recognition and unknown word handling.
  • BACKGROUND: Biomedical text mining may target various kinds of valuable information embedded in the literature, but a critical obstacle to the extension of the mining targets is the cost of manual construction of labeled data, which are required for state-of-the-art supervised learning systems.
  • Active learning is to choose the most informative documents for the supervised learning in order to reduce the amount of required manual annotations.
  • Previous works of active learning, however, focused on the tasks of entity recognition and protein-protein interactions, but not on event extraction tasks for multiple event types.
  • They also did not consider the evidence of event participants, which might be a clue for the presence of events in unlabeled documents.
  • Moreover, the confidence scores of events produced by event extraction systems are not reliable for ranking documents in terms of informativity for supervised learning.
  • We here propose a novel committee-based active learning method that supports multi-event extraction tasks and employs a new statistical method for informativity estimation instead of using the confidence scores from event extraction systems.
  • METHODS: Our method is based on a committee of two systems as follows: We first employ an event extraction system to filter potential false negatives among unlabeled documents, from which the system does not extract any event.
  • We then develop a statistical method to rank the potential false negatives of unlabeled documents 1) by using a language model that measures the probabilities of the expression of multiple events in documents and 2) by using a named entity recognition system that locates the named entities that can be event arguments (e.g. proteins).
  • The proposed method further deals with unknown words in test data by using word similarity measures.
  • We also apply our active learning method for the task of named entity recognition.
  • RESULTS AND CONCLUSION: We evaluate the proposed method against the BioNLP Shared Tasks datasets, and show that our method can achieve better performance than such previous methods as entropy and Gibbs error based methods and a conventional committee-based method.
  • We also show that the incorporation of named entity recognition into the active learning for event extraction and the unknown word handling further improve the active learning method.
  • In addition, the adaptation of the active learning method into named entity recognition tasks also improves the document selection for manual annotation of named entities.
  • [MeSH-major] Biological Ontologies. Data Mining / methods. Machine Learning. Natural Language Processing
  • [MeSH-minor] Statistics as Topic

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  • (PMID = 27127603.001).
  • [ISSN] 2041-1480
  • [Journal-full-title] Journal of biomedical semantics
  • [ISO-abbreviation] J Biomed Semantics
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4849099
  • [Keywords] NOTNLM ; Active learning / Biomedical natural language processing / Information extraction
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7. Kim JJ, Krupa DJ, Thompson RF: Inhibitory cerebello-olivary projections and blocking effect in classical conditioning. Science; 1998 Jan 23;279(5350):570-3
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  • [Title] Inhibitory cerebello-olivary projections and blocking effect in classical conditioning.
  • The behavioral phenomenon of blocking indicates that the informational relationship between the conditioned stimulus and the unconditioned stimulus is essential in classical conditioning.
  • The eyeblink conditioning paradigm is used to describe a neural mechanism that mediates blocking.
  • Disrupting inhibition of the inferior olive, a structure that conveys unconditioned stimulus information (airpuff) to the cerebellum prevented blocking in rabbits.
  • Recordings of cerebellar neuronal activity show that the inferior olive input to the cerebellum becomes suppressed as learning occurs.
  • These results suggest that the inferior olive becomes functionally inhibited by the cerebellum during conditioning, and that this negative feedback process might be the neural mechanism mediating blocking.
  • [MeSH-major] Cerebellum / physiology. Conditioning, Classical. Olivary Nucleus / physiology. Purkinje Cells / physiology
  • [MeSH-minor] Action Potentials. Animals. Blinking. Evoked Potentials. Feedback. Neural Pathways. Picrotoxin / pharmacology. Rabbits. gamma-Aminobutyric Acid / physiology

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  • (PMID = 9438852.001).
  • [ISSN] 0036-8075
  • [Journal-full-title] Science (New York, N.Y.)
  • [ISO-abbreviation] Science
  • [Language] eng
  • [Grant] United States / ACF HHS / AF / AF05142
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 124-87-8 / Picrotoxin; 56-12-2 / gamma-Aminobutyric Acid
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8. Kim JJ, Chae S, Jeong KH: Micropatterned single lens for wide-angle light-emitting diodes. Opt Lett; 2010 Mar 15;35(6):823-5
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  • [Title] Micropatterned single lens for wide-angle light-emitting diodes.
  • This work presents a simple and effective method for a wide-angle light-emitting diode module by using a single lens corrugated with micropattern arrays.
  • Impinged onto the micropattern arrays of a curved surface, light undergoes an enhancement of the illumination angle due to omnidirectional diffraction.
  • A hemispherical dome lens with micropattern arrays is microfabricated by a reconfigurable microtemplating and a replica molding method.
  • Depending on the micropattern size, the experimental and simulation results show the micropatterned single lens has the wide illumination angle as well as the high extraction efficiency of an incoming LED light source, compared with a conventional dome lens.
  • [MeSH-major] Lenses. Light
  • [MeSH-minor] Electrodes. Lighting. Microscopy, Electron, Scanning. Surface Properties

  • The Lens. Cited by Patents in .
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  • (PMID = 20237611.001).
  • [ISSN] 1539-4794
  • [Journal-full-title] Optics letters
  • [ISO-abbreviation] Opt Lett
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
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9. Shin K, Kim JJ, Suh KD: A facile process for generating monolithic-structured nano-silica/polystyrene multi-core/shell microspheres by a seeded sol-gel process method. J Colloid Interface Sci; 2010 Oct 15;350(2):581-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] A facile process for generating monolithic-structured nano-silica/polystyrene multi-core/shell microspheres by a seeded sol-gel process method.
  • Monodisperse "monolithic-structured" organic-inorganic composite microspheres were produced by a seeded sol-gel process method.
  • A large number of nano-silica particles were generated and dispersed in the inner domains of the obtained microspheres.
  • Seed particles were prepared by dispersion co-polymerization of styrene and (trimethoxysilyl)propyl 2-methylprop-2-enoate (TMSPM).
  • The seed particles were swollen with an emulsified tetraethoxysilane (TEOS) in 0.25 wt.
  • % sodium dodecylsulfate (SDS) aqueous solutions.
  • Then the sol-gel reaction was conducted with ammonium hydroxide after completion of the swelling process.
  • In contrast to conventional methods, the sol-gel reaction occurred in the inner space of the prepared template particles and monolithic-structured nano-silica and polystyrene organic-inorganic composite microspheres were obtained.
  • The synthetic procedure for composite particles was studied by utilizing transmission electron microscopy (TEM), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FT-IR), and thermo-gravimetric analysis (TGA).

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  • [Copyright] Copyright 2010 Elsevier Inc. All rights reserved.
  • (PMID = 20684960.001).
  • [ISSN] 1095-7103
  • [Journal-full-title] Journal of colloid and interface science
  • [ISO-abbreviation] J Colloid Interface Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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10. Kim MJ, Kim JJ, Kim SM: Endometrial evaluation with transvaginal ultrasonography for the screening of endometrial hyperplasia or cancer in premenopausal and perimenopausal women. Obstet Gynecol Sci; 2016 May;59(3):192-200
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Endometrial evaluation with transvaginal ultrasonography for the screening of endometrial hyperplasia or cancer in premenopausal and perimenopausal women.
  • OBJECTIVE: The aim of our study is to determine clinical factors and sonographic findings associated with endometrial hyperplasia or cancer (EH+) in premenopausal and perimenopausal women.
  • METHODS: A total of 14,340 transvaginal ultrasonography examinations of 9,888 healthy premenopausal and perimenopausal women were included in this retrospective study.
  • One hundred sixty-two subjects underwent endometrial biopsy based on abnormal uterine bleeding (AUB), sonographic endometrial abnormalities (thickened endometrium, endometrial mass, or endometrial stripe abnormality), or both.
  • The clinical factors and sonographic endometrial abnormalities were evaluated with regard to EH+.
  • RESULTS: Histologically verified EH+ was found in fourteen subjects (8.6%); ten cases of endometrial hyperplasia (EH) without atypia, three cases of EH with atypia (AEH), and one case of endometrial cancer.
  • Neither clinical factors nor AUB were associated with EH+ (P=0.32) or AEH+ (P=0.72).
  • Of sonographic findings, endometrial stripe abnormality was significantly associated with EH+ (P=0.003) and marginally associated with AEH+ (P=0.05), but a thickened endometrium was not associated with EH+ (P=0.43).
  • CONCLUSION: Endometrial stripe abnormality is a significant factor to predict EH+ in healthy premenopausal and perimenopausal women with and without AUB.
  • However, simple measurement of endometrial thickness has a limited role in this capacity.

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  • (PMID = 27200309.001).
  • [ISSN] 2287-8572
  • [Journal-full-title] Obstetrics & gynecology science
  • [ISO-abbreviation] Obstet Gynecol Sci
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4871935
  • [Keywords] NOTNLM ; Diagnosis / Endometrial hyperplasia / Endometrial neoplasms / Transvaginal ultrasonography
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