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Items 1 to 10 of about 529
1. Tomintz MN, Clarke GP, Rigby JE, Green JM: Optimising the location of antenatal classes. Midwifery; 2013 Jan;29(1):33-43
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Optimising the location of antenatal classes.
  • OBJECTIVES: To combine microsimulation and location-allocation techniques to determine antenatal class locations which minimise the distance travelled from home by potential users.
  • DESIGN: Microsimulation modeling and location-allocation modeling.
  • SETTING: City of Leeds, UK.
  • PARTICIPANTS: Potential users of antenatal classes.
  • METHODS: An individual-level microsimulation model was built to estimate the number of births for small areas by combining data from the UK Census 2001 and the Health Survey for England 2006.
  • Using this model as a proxy for service demand, we then used a location-allocation model to optimize locations.
  • FINDINGS: Different scenarios show the advantage of combining these methods to optimize (re)locating antenatal classes and therefore reduce inequalities in accessing services for pregnant women.
  • KEY CONCLUSIONS: Use of these techniques should lead to better use of resources by allowing planners to identify optimal locations of antenatal classes which minimise women's travel.
  • IMPLICATIONS FOR PRACTICE: These results are especially important for health-care planners tasked with the difficult issue of targeting scarce resources in a cost-efficient, but also effective or accessible, manner. (169 words).
  • [MeSH-major] Health Services Accessibility. Models, Organizational. Prenatal Care / methods. Prenatal Education / organization & administration
  • [MeSH-minor] Adult. Birth Rate. Female. Great Britain. Humans. Patient Acceptance of Health Care. Patient Care Planning. Pregnancy. Social Environment

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  • [Copyright] Copyright © 2011 Elsevier Ltd. All rights reserved.
  • (PMID = 23146138.001).
  • [ISSN] 1532-3099
  • [Journal-full-title] Midwifery
  • [ISO-abbreviation] Midwifery
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Scotland
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2. Green JM, Pritchett RC, Tucker DC, Crews TR, McLester JR: Sweat lactate response during cycling at 30 degrees C and 18 degrees C WBGT. J Sports Sci; 2004 Apr;22(4):321-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sweat lactate response during cycling at 30 degrees C and 18 degrees C WBGT.
  • Sweat lactate reflects eccrine gland metabolism.
  • However, the metabolic tendencies of eccrine glands in a hot versus thermoneutral environment are not well understood.
  • Sixteen male volunteers completed a maximal cycling trial and two 60-min cycling trials [30 degrees C = 30 +/- 1 degrees C and 18 degrees C = 18 +/- 1 degrees C wet bulb globe temperature (WBGT)].
  • The participants were requested to maintain a cadence of 60 rev min(-1) with the intensity individualized at approximately 90% of the ventilatory threshold.
  • Sweat samples at 10, 20, 30, 40, 50 and 60 min were analysed for lactate concentration.
  • Sweat rate at 30 degrees C (1380 +/- 325 ml x h(-1)) was significantly greater (P < 0.05) than at 18 degrees C (632 +/- 311 ml x h(-1)).
  • Sweat lactate concentration was significantly greater (P < 0.05) at each time point during the 18 degrees C trial, with values between trials tending to converge across time.
  • During the 30 degrees C trial, both heart rate (20, 30, 40, 50 and 60 min) and rectal temperature (30, 40, 50 and 60 min) were significantly higher than in the 18 degrees C trial.
  • Higher sweat lactate concentrations coupled with lower sweat rates may indicate a greater relative contribution of oxygen-independent metabolism within eccrine glands during exercise at 18 degrees C.
  • Decreases in sweat lactate concentration across time suggest either greater dilution due to greater sweat volume or increased reliance on aerobic metabolism within eccrine glands.
  • The convergence of lactate concentrations between trials may indicate that time-dependent modifications in sweat gland metabolism occur at different rates contingent partially on environmental conditions.
  • [MeSH-major] Bicycling / physiology. Eccrine Glands / metabolism. Lactates / analysis. Sweating / physiology
  • [MeSH-minor] Adult. Analysis of Variance. Body Temperature Regulation / physiology. Exercise Test. Humans. Male. Physical Exertion. Physical Fitness. Prospective Studies. Sweat / chemistry. Temperature

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  • (PMID = 15161105.001).
  • [ISSN] 0264-0414
  • [Journal-full-title] Journal of sports sciences
  • [ISO-abbreviation] J Sports Sci
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Lactates
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3. Green JM: Category cues in free recall: retarded adults of two vocabulary age levels. Am J Ment Defic; 1974 Jan;78(4):419-25
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  • [Title] Category cues in free recall: retarded adults of two vocabulary age levels.
  • [MeSH-major] Association. Cues. Intellectual Disability. Memory
  • [MeSH-minor] Adolescent. Adult. Education of Intellectually Disabled. Female. Humans. Intelligence Tests. Male. Vocabulary

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  • (PMID = 4812938.001).
  • [ISSN] 0002-9351
  • [Journal-full-title] American journal of mental deficiency
  • [ISO-abbreviation] Am J Ment Defic
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] UNITED STATES
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4. Larimer CM, Slavnic D, Pitstick LD, Green JM: Comparison of Substrate Specificity of &lt;i&gt;Escherichia Coli p&lt;/i&gt;-Aminobenzoyl-Glutamate Hydrolase with &lt;i&gt;Pseudomonas&lt;/i&gt; Carboxypeptidase G. Adv Enzyme Res; 2014 Mar;2(1):39-48
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Comparison of Substrate Specificity of <i>Escherichia Coli p</i>-Aminobenzoyl-Glutamate Hydrolase with <i>Pseudomonas</i> Carboxypeptidase G.
  • : Reduced folic acid derivatives support biosynthesis of DNA, RNA and amino acids in bacteria as well as in eukaryotes, including humans.
  • While the genes and steps for bacterial folic acid synthesis are known, those associated with folic acid catabolism are not well understood.
  • A folate catabolite found in both humans and bacteria is <i>p</i>-aminobenzoyl-glutamate (PABA-GLU).
  • The enzyme <i>p</i>-aminobenzoyl-glutamate hydrolase (PGH) breaks down PABA-GLU and is part of an apparent operon, the <i>abg</i> region, in <i>E. coli</i>.
  • The subunits of PGH possess sequence and catalytic similarities to carboxypeptidase enzymes from <i>Pseudomonas</i> species.
  • A comparison of the subunit sequences and activity of PGH, relative to carboxypeptidase enzymes, may lead to a better understanding of bacterial physiology and pathway evolution.
  • We first compared the amino acid sequences of AbgA, AbgB and carboxypeptidase G<sub>2</sub> from <i>Pseudomonas sp.
  • </i> RS-16, which has been crystallized.
  • Then we compared the enzyme activities of <i>E. coli</i> PGH and commercially available <i>Pseudomonas</i> carboxypeptidase G using spectrophotometric assays measuring cleavage of PABA-GLU, folate, aminopterin, methotrexate, 5-formyltetrahydrofolate, and 5-methyltetrahydrofolate.
  • The <i>K<sub>m</sub></i> and <i>V</i><sub>max</sub> values for the folate and anti-folate substrates of PGH could not be determined, because the instrument reached its limit before the enzyme was saturated.
  • Therefore, activity of PGH was compared to the activity of CPG, or normalized to PABA-GLU (nmole/min/µg).
  • Relative to its activity with 10 µM PABA-GLU (100%), PGH cleaved glutamate from methotrexate (48%), aminopterin (45%) and folate (9%).
  • Reduced folates leucovorin (5-formyltetrahydrofolate) and 5-methyltetrahydrofolate were not cleaved by PGH.
  • Our data suggest that <i>E. coli</i> PGH is specific for PABA-GLU as its activity with natural folates (folate, 5-methyltetrahydrofolate, and leucovorin) was very poor.
  • It does, however, have some ability to cleave anti-folates which may have clinical applications in treatment of chemotherapy overdose.

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  • (PMID = 27795973.001).
  • [ISSN] 2328-4846
  • [Journal-full-title] Advances in enzyme research
  • [ISO-abbreviation] Adv Enzyme Res
  • [Language] eng
  • [Grant] United States / NIGMS NIH HHS / GM / R15 GM085760
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Carboxypeptidase G / Folate Catabolism / p-Aminobenzoyl-Glutamate Hydrolase
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5. Wang W, Link V, Green JM: Identification and cloning of a CD43-associated serine/threonine kinase. Cell Immunol; 2000 Oct 10;205(1):34-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Identification and cloning of a CD43-associated serine/threonine kinase.
  • CD43 is expressed on most hematopoetic cells and has been shown to regulate the activation and adhesion of T cells.
  • We have cloned a serine/threonine kinase that can interact with the cytoplasmic domain of CD43.
  • This protein is expressed in multiple tissues, including lymphoid cells.
  • Analysis of the subcellular localization reveals it to be present in both the nucleus and the cytoplasm of the cell.
  • The identification of this protein suggests that CD43 may mediate its biologic effects through activation of a kinase cascade, resulting in the regulation of cell growth.
  • [MeSH-major] Antigens, CD. Carrier Proteins. Protein-Serine-Threonine Kinases / metabolism. Repressor Proteins. Sialoglycoproteins / metabolism
  • [MeSH-minor] Amino Acid Sequence. Animals. Antigens, CD43. Cloning, Molecular. Mice. Molecular Sequence Data. Protein Binding. Sequence Homology, Amino Acid. Tissue Distribution. Two-Hybrid System Techniques

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  • [Copyright] Copyright 2000 Academic Press.
  • (PMID = 11078605.001).
  • [ISSN] 0008-8749
  • [Journal-full-title] Cellular immunology
  • [ISO-abbreviation] Cell. Immunol.
  • [Language] eng
  • [Databank-accession-numbers] GENBANK/ AF273680
  • [Publication-type] Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
  • [Publication-country] UNITED STATES
  • [Chemical-registry-number] 0 / Antigens, CD; 0 / Antigens, CD43; 0 / Carrier Proteins; 0 / Repressor Proteins; 0 / Sialoglycoproteins; 0 / Spn protein, mouse; EC 2.7.1.- / Hipk2 protein, mouse; EC 2.7.11.1 / Protein-Serine-Threonine Kinases
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6. Lang S, Lawrence CJ, Orme RL: Cup feeding: an alternative method of infant feeding. Arch Dis Child; 1994 Oct;71(4):365-9
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  • [Title] Cup feeding: an alternative method of infant feeding.
  • [MeSH-major] Infant Equipment. Infant Nutritional Physiological Phenomena. Infant, Premature. Milk, Human
  • [MeSH-minor] Breast Feeding. Cleft Lip / therapy. Cleft Palate / therapy. Female. Humans. Infant, Newborn. Male

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  • (PMID = 7979537.001).
  • [ISSN] 1468-2044
  • [Journal-full-title] Archives of disease in childhood
  • [ISO-abbreviation] Arch. Dis. Child.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] ENGLAND
  • [Other-IDs] NLM/ PMC1030024
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7. Mahamaneerat WK, Shyu CR: Knowledge discovery using Domain-Concept Mining approach for the Behavioral Risk Factor Surveillance System (BRFSS) data. AMIA Annu Symp Proc; 2006;:1021
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  • [Title] Knowledge discovery using Domain-Concept Mining approach for the Behavioral Risk Factor Surveillance System (BRFSS) data.
  • The publicly available Behavioral Risk Factor Surveillance System (BRFSS) data is the largest telephone survey data set in the world.
  • Often times, the data set is under-utilized due to its size and the difficulties to comprehend and explore the relationships among variables.
  • With a traditional data mining approach, such as association rule (AR) mining, it is still not possible to discover valuable information under the existing computational power.
  • To promote the usefulness of this rich data set efficiently, we propose a novel data mining approach called Domain-Concept Mining (DCM) that partitions data into groups of relevant domain-concept, then extracts associations among variables from each partition.
  • The findings from the DCM show that it can efficiently discover relevant information from the BRFSS with respect to the previously published literature.

  • NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .
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  • (PMID = 17238640.001).
  • [ISSN] 1942-597X
  • [Journal-full-title] AMIA ... Annual Symposium proceedings. AMIA Symposium
  • [ISO-abbreviation] AMIA Annu Symp Proc
  • [Language] ENG
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC1839664
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8. GREEN JM, GREENE EI, SCHUMER W: Treatment of polyps of the colon. Am J Proctol; 1956 Oct;7(5):397-401
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Treatment of polyps of the colon.
  • [MeSH-major] Colonic Neoplasms. Polyps / surgery. Rectal Neoplasms. Rectum

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  • (PMID = 13362617.001).
  • [ISSN] 0002-9521
  • [Journal-full-title] American journal of proctology
  • [ISO-abbreviation] Am J Proctol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Not Available
  • [Other-IDs] CLML/ 5731:8736
  • [Keywords] NLM ; COLON/neoplasms (major topic) / POLYPI/surgery (major topic) / RECTUM/neoplasms (major topic)
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9. Abarikwu SO, Njoku RC, Lawrence CJ, Charles IA, Ikewuchi JC: Rutin ameliorates oxidative stress and preserves hepatic and renal functions following exposure to cadmium and ethanol. Pharm Biol; 2017 Dec;55(1):2161-2169
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Rutin ameliorates oxidative stress and preserves hepatic and renal functions following exposure to cadmium and ethanol.
  • CONTEXT: Rutin (RUT) is an antioxidant flavonoid with well-known metal chelating potentials.
  • OBJECTIVE: This study was designed to evaluate the protective effects of RUT against cadmium (Cd) + ethanol (EtOH)-induced hepatic and renal toxicity in rats.
  • MATERIALS AND METHODS: Wistar rats were treated with Cd (50 mg/kg) alone or in combination with EtOH (5 mg/kg) and RUT (25, 50 and 100 mg/kg) for 15 days.
  • After treatment, the liver, kidney and serum were removed for biochemical assays by spectrophotometric methods.
  • RESULTS: Serum, hepatic and renal malondialdehyde (MDA) levels were highest in the Cd + EtOH group and lowest in Cd + EtOH animals co-treated with the highest dose of RUT (2.98 ± 0.34, 10.08 ± 2.32, 4.99 ± 1.21 vs. 1.69 ± 0.33, 6.13 ± 0.28, 3.66 ± 1.12 μmol MDA/mg protein, respectively).
  • The serum level of Cd was increased in the Cd + EtOH treated animals compared to Cd + EtOH animals co-treated with 100 mg/kg RUT (2.54 ± 0.08 vs. 1.28 ± 0.04 ppm).
  • Furthermore, RUT at the highest dose protected against Cd + EtOH-induced elevation of bilirubin and uric acid levels as well as activities of lactate dehydrogenase and γ-glutamyl transferase (62.86 ± 2.74 vs. 122.52 ± 6.35 µmol/L; 1.77 ± 0.35 vs. 3.23 ± 0.55 mmol/L; 9.56 ± 1.22 vs. 16.21 ± 1.64 U/L; 288.92 ± 40.12 vs. 159.8 ± 18.01 U/L).
  • The histo-pathological changes in the liver and kidney were also reduced in the Cd + EtOH animals co-treated with RUT in a dose-dependent manner.
  • DISCUSSION AND CONCLUSION: RUT protected against the combined effects of Cd + EtOH on hepatic and renal functions and improved the antioxidant defence system in the blood.

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  • (PMID = 29025321.001).
  • [ISSN] 1744-5116
  • [Journal-full-title] Pharmaceutical biology
  • [ISO-abbreviation] Pharm Biol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Serum / antioxidant / kidney / liver / phytochemicals
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10. Green JM, Edwards KJ, Usher SL, Barker JH, Marshall EJ, Froud-Williams RJ, Karp A: Microsatellites for Barren Brome (Anisantha sterilis). Mol Ecol; 2000 Dec;9(12):2195-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Microsatellites for Barren Brome (Anisantha sterilis).
  • [MeSH-major] Microsatellite Repeats. Poaceae / genetics
  • [MeSH-minor] Gene Library. Genetic Variation. Genome, Plant

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  • (PMID = 11123650.001).
  • [ISSN] 0962-1083
  • [Journal-full-title] Molecular ecology
  • [ISO-abbreviation] Mol. Ecol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] ENGLAND
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