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1. Nishida Y, Tsukushi S, Urakawa H, Hamada S, Kozawa E, Ikuta K, Ando Y, Ishiguro N: Low-dose chemotherapy with methotrexate and vinblastine for patients with desmoid tumors: relationship to CTNNB1 mutation status. Int J Clin Oncol; 2015 Dec;20(6):1211-7
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  • [Title] Low-dose chemotherapy with methotrexate and vinblastine for patients with desmoid tumors: relationship to CTNNB1 mutation status.
  • BACKGROUND: This study was conducted to determine the efficacy and safety of low-dose chemotherapy with methotrexate (MTX) and vinblastine (VBL) for patients with desmoid tumors refractory to meloxicam treatment, focusing in particular on the relationship between the efficacy of this chemotherapy and catenin β-1 (CTNNB1) mutation status.
  • PATIENTS AND METHODS: Since March 2003, patients pathologically diagnosed with extraperitoneal desmoid tumors have been prospectively treated with meloxicam, a COX-2 inhibitor, at our institution.
  • Only one patient presented disease progression.
  • [MeSH-major] Antineoplastic Combined Chemotherapy Protocols / administration & dosage. Fibromatosis, Abdominal / drug therapy. Fibromatosis, Abdominal / genetics. beta Catenin / genetics

  • Hazardous Substances Data Bank. METHOTREXATE .
  • Hazardous Substances Data Bank. Meloxicam .
  • Hazardous Substances Data Bank. VINBLASTINE .
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  • (PMID = 25899770.001).
  • [ISSN] 1437-7772
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / CTNNB1 protein, human; 0 / Cyclooxygenase 2 Inhibitors; 0 / Thiazines; 0 / Thiazoles; 0 / beta Catenin; 5V9KLZ54CY / Vinblastine; VG2QF83CGL / meloxicam; YL5FZ2Y5U1 / Methotrexate
  • [Keywords] NOTNLM ; CTNNB1 / Desmoid tumor / Methotrexate / Vinblastine
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2. Khomiakov VM, Cheremisov VV, Chaĭka AV, Vashakmadze LA, Dar'ialova SL, Novikova OV, Kostrygin AK: [Experience of surgical treatment of abdominal and intraabdominal desmoid fibromas]. Khirurgiia (Mosk); 2014;(11):17-25
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  • [Title] [Experience of surgical treatment of abdominal and intraabdominal desmoid fibromas].
  • It is presented the treatment results of abdominal and intraabdominal desmoid fibromas.
  • Group of abdominal localization included 19 patients.
  • Tumor removal was associated with plastic of abdominal wall by synthetic implant in 17 patients.
  • Wide excision of surrounding tissues and musculo-aponeurotic layer of anterior abdominal wall allows to achieve long-term disease-free period.
  • The second group included 28 patients with intraabdominal desmoid fibromas.
  • Explorative laparotomy was used in 3 (21.4%) cases because of involvement of mesenteric vessels.
  • 14 (50%) patients received conservative therapy because of unresectable tumor including chemo-, hormone- and radiotherapy.
  • Cytoreductive (R1/R2) volume is admitted for intraabdominal desmoid fibromas.
  • But even in case of unresectable process and explorative intervention stabilization and regression of tumor is possible by means of chemo-, hormone- and radiotherapy in different combination.
  • [MeSH-major] Abdominal Cavity. Cytoreduction Surgical Procedures. Dissection. Fibromatosis, Abdominal. Laparotomy. Neoplasm Recurrence, Local. Postoperative Complications / prevention & control
  • [MeSH-minor] Abdominal Wall / pathology. Abdominal Wall / surgery. Abdominal Wound Closure Techniques. Adult. Combined Modality Therapy. Female. Humans. Male. Moscow. Retrospective Studies. Treatment Outcome

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  • (PMID = 25589179.001).
  • [ISSN] 0023-1207
  • [Journal-full-title] Khirurgiia
  • [ISO-abbreviation] Khirurgiia (Mosk)
  • [Language] rus
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Russia (Federation)
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3. Kovačević K, Obad-Kovačević D, Popić-Ramač J: Sporadic giant intra-abdominal desmoid tumor: A radiological case report. Mol Clin Oncol; 2017 Jun;6(6):896-898
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  • [Title] Sporadic giant intra-abdominal desmoid tumor: A radiological case report.
  • Desmoid tumor (DT) is a locally invasive form of fibromatosis, comprising only 0.03% of all tumors.
  • DTs occur more frequently in patients with familial adenomatous polyposis and Gardner's syndrome, as intra-abdominal or anterior abdominal wall tumors, whereas sporadic DTs are more likely to be extra-abdominal (only 5% of sporadic DTs are intra-abdominal).
  • Imaging studies, such as computed tomography (CT) and magnetic resonance imaging (MRI) are used for preoperative diagnosis and for the planning of the surgery.
  • Following surgery, CT and MRI are used to detect recurrence and to monitor the tumor's response to radiotherapy or medical therapy for unresectable or recurrent tumors.
  • We herein report a rare case of a sporadic giant intra-abdominal DT in a 28-year-old female patient without any predisposing factors, and highlight the importance of including DT in the differential diagnosis of huge intra-abdominal masses.

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  • (PMID = 28588785.001).
  • [ISSN] 2049-9450
  • [Journal-full-title] Molecular and clinical oncology
  • [ISO-abbreviation] Mol Clin Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; abdomen / benign tumor / computed tomography / desmoid tumor / oncology
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4. van Broekhoven DL, Grünhagenl DJ, van Dalen T, van Coevorden F, Bonenkamp HJ, Been LB, Bemelmans MH, Dijkstra SD, Colombo C, Gronchi A, Verhoef C: Tailored Beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention. BMC Cancer; 2016 Aug 26;16:686
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Tailored Beta-catenin mutational approach in extra-abdominal sporadic desmoid tumor patients without therapeutic intervention.
  • BACKGROUND: The efficacy of the classical treatment modalities surgery and radiotherapy in the treatment of aggressive fibromatosis is presently disputed and there is a shift towards a more conservative approach.
  • The aim of the present study is to objectify tumor growth in patients with extra-abdominal or abdominal wall aggressive fibromatosis, while adhering to a "watchful waiting" policy.
  • Other objectives are to investigate quality of life and to identify factors associated with tumor growth, in particular the relation with the presence of a CTNNB1-gene mutation in the tumor.
  • All patients with extra-abdominal or abdominal wall aggressive fibromatosis are eligible for inclusion in the study.
  • Main exclusion criteria are: history of familiar adenomatous polyposis, severe pain, functional impairment, life/limb threating situations in case of progressive disease.
  • Secondary endpoints are quality of life and the rate of influence on tumor progression for several factors, such as CTNNB1-mutations, age and localization.
  • DISCUSSION: This study will provide insight in tumor behavior, the effect on quality of life and clinicopathological factors predictive of tumor progression.
  • [MeSH-major] Abdominal Neoplasms / complications. Abdominal Neoplasms / pathology. Adenomatous Polyposis Coli / complications. Adenomatous Polyposis Coli / pathology. Fibromatosis, Aggressive / complications. Fibromatosis, Aggressive / pathology. Research Design
  • [MeSH-minor] Adult. Aged. DNA Mutational Analysis. Disease Progression. Female. Humans. Male. Middle Aged. Mutation. Netherlands. Quality of Life. Watchful Waiting. beta Catenin / genetics

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  • (PMID = 27565718.001).
  • [ISSN] 1471-2407
  • [Journal-full-title] BMC cancer
  • [ISO-abbreviation] BMC Cancer
  • [Language] eng
  • [Publication-type] Journal Article; Multicenter Study; Observational Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / beta Catenin; Desmoid disease, hereditary
  • [Other-IDs] NLM/ PMC5000483
  • [Keywords] NOTNLM ; Aggressive fibromatosis / Desmoid / Desmoid-type fibromatosis / Growth / Progression / Wait-and-see / Watchful waiting
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6. Inoue Y, Ishida H, Ueno H, Kobayashi H, Yamaguchi T, Konishi T, Tomita N, Matsubara N, Ishida F, Hinoi T, Kanemitsu Y, Watanabe T, Sugihara K: The treatment of desmoid tumors associated with familial adenomatous polyposis: the results of a Japanese multicenter observational study. Surg Today; 2017 Mar 01;
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  • [Title] The treatment of desmoid tumors associated with familial adenomatous polyposis: the results of a Japanese multicenter observational study.
  • PURPOSE: Familial adenomatous polyposis (FAP)-associated desmoid tumor (DT) is sometimes life threatening.
  • The selection of treatment for intra-abdominal DTs was also evaluated according to Church's classification.
  • RESULTS: Surgery was frequently used to treat extra-abdominal DTs.
  • Multimodal treatments, including surgery, and the administration of non-steroidal anti-inflammatory drugs, hormonal therapy, and chemotherapy were widely used for intra-abdominal DTs.
  • The most effective pharmacological treatment was cytotoxic chemotherapy, which was associated with a response rate of 45.5% and a disease control rate of 72.7%.
  • After a median follow-up period of 53.0 months, the 5-year DT-specific survival rate in patients with stage IV disease was 71.4%; in contrast, the rate in patients with other stages was 100%.
  • CONCLUSION: Our findings will provide clues that may help physicians in selecting the optimal strategy for this rare disease.

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  • (PMID = 28251376.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Chemotherapy / Desmoid tumor / Familial adenomatous polyposis / Pharmacological treatment
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7. Yamano T, Hamanaka M, Babaya A, Kimura K, Kobayashi M, Fukumoto M, Tsukamoto K, Noda M, Matsubara N, Tomita N, Sugihara K: Management strategies in Lynch syndrome and familial adenomatous polyposis: a national healthcare survey in Japan. Cancer Sci; 2017 Feb;108(2):243-249
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Management of desmoid tumor in the abdominal cavity differed according to the number of patients treated.
  • [MeSH-minor] Anti-Inflammatory Agents, Non-Steroidal / therapeutic use. Cancer Care Facilities / statistics & numerical data. Colectomy / statistics & numerical data. Female. Fibromatosis, Aggressive. Genetic Counseling / statistics & numerical data. Hospitals / statistics & numerical data. Humans. Japan / epidemiology. Male. Proctocolectomy, Restorative / statistics & numerical data. Referral and Consultation / statistics & numerical data. Surveys and Questionnaires

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  • [Copyright] © 2016 The Authors. Cancer Science published by John Wiley & Sons Australia, Ltd on behalf of Japanese Cancer Association.
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  • (PMID = 27870147.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Anti-Inflammatory Agents, Non-Steroidal
  • [Keywords] NOTNLM ; Disease management / Japanese / Lynch syndrome / familial adenomatous polyposis / screening
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8. Ogawa N, Iseki H, Tsunozaki H, Hayashi M, Baba H, Matsuyama T, Uetake H, Sugihara K: Intra-abdominal desmoid tumor difficult to distinguish from a gastrointestinal stromal tumor: report of two cases. Surg Today; 2014 Nov;44(11):2174-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-abdominal desmoid tumor difficult to distinguish from a gastrointestinal stromal tumor: report of two cases.
  • Desmoid tumors are benign fibroblastic neoplasms with no metastatic potential, but a propensity for local recurrence even after complete surgical resection.
  • These lesions can develop at any site in the body, and commonly occur in the intra-abdominal area.
  • Intra-abdominal desmoid tumors usually occur at the mesentery or retroperitoneum, and may morphologically mimic gastrointestinal stromal tumors (GISTs).
  • We herein report the cases of two patients with sporadic intra-abdominal desmoid tumors that were differentiated from GIST by immunohistological examination using beta-catenin and CD34.
  • Desmoid tumors specifically express nuclear beta-catenin, and show no expression of CD34.
  • We recommend staining for beta-catenin and CD34 when an intra-abdominal desmoid tumor is suspected.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Biomarkers, Tumor / analysis. Fibromatosis, Aggressive / diagnosis
  • [MeSH-minor] Aged. Antigens, CD34 / analysis. Diagnosis, Differential. Female. Gastrointestinal Neoplasms / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. Humans. Immunohistochemistry. Magnetic Resonance Imaging. Male. Middle Aged. Proto-Oncogene Proteins c-kit / analysis. Tomography, X-Ray Computed. beta Catenin / analysis

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  • (PMID = 23955477.001).
  • [ISSN] 1436-2813
  • [Journal-full-title] Surgery today
  • [ISO-abbreviation] Surg. Today
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / Antigens, CD34; 0 / Biomarkers, Tumor; 0 / beta Catenin; EC 2.7.10.1 / Proto-Oncogene Proteins c-kit
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9. Dufresne A, Paturel M, Alberti L, Philippon H, Duc A, Decouvelaere AV, Cassier P, Blay JY: Prediction of desmoid tumor progression using miRNA expression profiling. Cancer Sci; 2015 May;106(5):650-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prediction of desmoid tumor progression using miRNA expression profiling.
  • Desmoid tumor is a rare connective tissue tumor with locoregional aggressiveness but unpredictable behavior.
  • A more precise miRNA signature must now be determined to select patients who would not benefit from surgical resection of their tumor and who ought to be monitored without treatment.
  • [MeSH-major] Fibromatosis, Aggressive / genetics. Fibromatosis, Aggressive / pathology. Gene Expression Profiling. MicroRNAs / analysis
  • [MeSH-minor] Abdominal Neoplasms / drug therapy. Abdominal Neoplasms / genetics. Abdominal Neoplasms / pathology. Adult. Aged. Benzamides / therapeutic use. Biomarkers, Tumor / genetics. Female. Gene Expression Regulation, Neoplastic. Humans. Imatinib Mesylate. Logistic Models. Male. Middle Aged. Piperazines / therapeutic use. Prognosis. Pyrimidines / therapeutic use. Retrospective Studies. Young Adult

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  • [Copyright] © 2015 The Authors. Cancer Science published by Wiley Publishing Asia Pty Ltd on behalf of Japanese Cancer Association.
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  • (PMID = 25707497.001).
  • [ISSN] 1349-7006
  • [Journal-full-title] Cancer science
  • [ISO-abbreviation] Cancer Sci.
  • [Language] eng
  • [Publication-type] Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Benzamides; 0 / Biomarkers, Tumor; 0 / MicroRNAs; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
  • [Other-IDs] NLM/ PMC4452168
  • [Keywords] NOTNLM ; Aggressive fibromatosis / desmoid tumor / imatinib / miRNA / prognosis
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10. Chika N, Kumamoto K, Suzuki O, Yamamoto A, Tajima Y, Watanabe Y, Onozawa H, Matsuzawa T, Eguchi H, Ishibashi K, Mochiki E, Ishida H: [A Case of a Desmoid Tumor the Developed Around Ileostomy in a Patient with FAP]. Gan To Kagaku Ryoho; 2015 Nov;42(12):1947-9
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A Case of a Desmoid Tumor the Developed Around Ileostomy in a Patient with FAP].
  • The patient was diagnosed with intraabdominal desmoid tumors, stage Ⅳ according to the Church's classification.
  • The desmoid tumor (15×9 cm) around the ileostomy was completely resected surgically, whereas another desmoid tumor (5×4 cm) was incompletely resected.
  • We found a desmoid tumor of more than 10 cm in size and many fibromatous plaques in the mesentery.
  • We then performed 4 courses of systemic chemotherapy with dacarbazine and doxorubicin in for the residual desmoid tumors after surgery.
  • There was no growth of the residual desmoid tumors for 12 months after chemotherapy.
  • Genetic tests detected a pathogenic germline mutation of the APC gene in the high-risk region of the desmoid tumor.
  • [MeSH-major] Abdominal Neoplasms / surgery. Adenomatous Polyposis Coli. Fibromatosis, Aggressive / surgery

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  • (PMID = 26805226.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] 0 / APC protein, human; 0 / Adenomatous Polyposis Coli Protein; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin
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11. Williams AD, Heightchew K, Siripirapu V: Diagnostic and therapeutic dilemmas in intra-abdominal desmoid tumors: A case report and literature review. Int J Surg Case Rep; 2016;26:150-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diagnostic and therapeutic dilemmas in intra-abdominal desmoid tumors: A case report and literature review.
  • INTRODUCTION: Intra-abdominal desmoid tumors (DTs) are a rare and anatomically diverse group of locally-aggressive, benign neoplasms.
  • They are often difficult to diagnose, even in patients who possess risk factors for the disease.
  • Even after a diagnosis has been reached, the optimal therapy is often not well-defined.
  • PRESENTATION OF CASE: The case discussed of a 33-year old male with a giant intra-abdominal desmoid is an example of both the diagnostic and therapeutic dilemmas that arise when confronted with a patient with a DT.
  • Initial confusion over diagnosis led to ineffective therapy, but once the correct diagnosis was made, the patient went on to definitive surgical resection.
  • DISCUSSION: The differential diagnosis of DTs is broad, and the diagnosis is often delayed due to nonspecific presentations.
  • Immunohistochemistry is crucial in the accurate histological diagnosis, which guides treatment.
  • CONCLUSION: DTs present a clinical challenge in their diagnosis and management, and despite providing standard medical and surgical treatment, recurrence rates are high and continued surveillance is crucial.

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  • [Copyright] Copyright © 2016 The Author(s). Published by Elsevier Ltd.. All rights reserved.
  • (PMID = 27494372.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4976140
  • [Keywords] NOTNLM ; Case report / Desmoid tumor / Immunohistochemistry / Mesenteric fibromatosis / Surgery
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12. Li P, Zhang Z, Qin S, Li J: The diagnosis of mesenteric fibromatosis: A 90-month five patients case report. J Cancer Res Ther; 2016 Oct-Dec;12(4):1318-1320
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  • [Title] The diagnosis of mesenteric fibromatosis: A 90-month five patients case report.
  • Mesenteric fibromatosis (MF) is a rare tumor (2-4 cases per 1 million people annually) with few presented features.
  • [MeSH-major] Fibroma / diagnosis. Mesentery / pathology. Peritoneal Neoplasms / diagnosis

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  • (PMID = 28169246.001).
  • [ISSN] 1998-4138
  • [Journal-full-title] Journal of cancer research and therapeutics
  • [ISO-abbreviation] J Cancer Res Ther
  • [Language] eng
  • [Publication-type] Case Reports; Letter
  • [Publication-country] India
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13. Bn A, Cd JK, Ps S, M M, Urs R: Giant aggressive mesenteric fibromatosis- a case report. J Clin Diagn Res; 2015 Feb;9(2):PD07-8
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  • [Title] Giant aggressive mesenteric fibromatosis- a case report.
  • Fibromatosis are rare, accounting for 0.03% of all tumours.
  • Mesenteric fibromatosis is a very rare (8% of all desmoid neoplasm).
  • Aggressive fibromatosis of mesentery is a rare surgical problem affecting 2-4 per million people.
  • Here, we are discussing about 24-year-old male presented with progressive abdomen distension associated with pain since one month.
  • Abdominal examination showed a firm non-tender intra-abdominal mass, measuring around 15x14 cm size, with intrinsic mobility, which was perpendicular to mesenteric line, all borders were well-made out.
  • CECT abdomen showed features suggestive of GIST .
  • Immunohistochemistry showed Beta Catenin +ve, CD 117-ve, CD 34 -ve and SMA-ve, which is confirmative of Fibromatosis.

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  • (PMID = 25859491.001).
  • [ISSN] 2249-782X
  • [Journal-full-title] Journal of clinical and diagnostic research : JCDR
  • [ISO-abbreviation] J Clin Diagn Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4378773
  • [Keywords] NOTNLM ; Beta catenin / Desmoid tumour / Estrogen / Gist
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14. Vural B, Vural F, Müezzinoglu B: An Abdominal Wall Desmoid Tumour Mimicking Cesarean Scar Endometriomas: A Case Report and Review of the Literature. J Clin Diagn Res; 2015 Sep;9(9):QD14-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] An Abdominal Wall Desmoid Tumour Mimicking Cesarean Scar Endometriomas: A Case Report and Review of the Literature.
  • Abdominal wall desmoid tumours (DT) are rare, slow-growing benign muscular-aponeurotic fibrous tumours with the tendency to locally invade and recur.
  • Abdominal wall endometriosis is also an unusual disease, and preoperative clinical diagnosis is not always easy.
  • Herein, we report an abdominal mass presenting as cyclic pain.
  • Forty-two years old woman who gave birth by cesarean section admitted the complaints of painful abdominal mass (78x45 mm in size) under her cesarean incision scar.
  • We performed wide surgical excision of mass with a 1 cm tumor-free margin with the diagnosis of a benign mesenchymal tumor in the frozen section.
  • This report presents a case of abdominal wall desmoid tumor mimicking endometrioma.
  • In this paper, shortcomings in diagnosis, abdominal wall endometriomas, and DTs were discussed in the view of literature.

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  • (PMID = 26500967.001).
  • [ISSN] 2249-782X
  • [Journal-full-title] Journal of clinical and diagnostic research : JCDR
  • [ISO-abbreviation] J Clin Diagn Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4606296
  • [Keywords] NOTNLM ; Abdominal wall masses / Benign mesenchymal tumor / Cesarean section / Endometriosis
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15. Seo YN, Park YM, Yoon HK, Lee SJ, Choo HJ, Ryu JH: Breast fibromatosis associated with breast implants. Jpn J Radiol; 2015 Sep;33(9):591-7
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Breast fibromatosis associated with breast implants.
  • Fibromatosis refers to an extra-abdominal desmoid tumor or aggressive fibromatosis.
  • Breast fibromatosis can develop in association with the capsule around a breast implant, although reports of cases of fibromatosis associated with breast implants are rare.
  • In the present report, we describe a case of breast fibromatosis that developed adjacent to a breast implant and demonstrated a relatively well-defined border even though it invaded the surrounding structures.
  • We also explore the specific imaging features for diagnosing breast fibromatosis in association with implants by reviewing previous literature.

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  • (PMID = 26213262.001).
  • [ISSN] 1867-108X
  • [Journal-full-title] Japanese journal of radiology
  • [ISO-abbreviation] Jpn J Radiol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Breast implant / Fibromatosis / Magnetic resonance imaging / Ultrasonography
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16. Jones L, Pares D, Tzouiliadis L, Higginson A, Senapati A: Desmoid tumor fistulating to small bowel. Tech Coloproctol; 2015 May;19(5):325-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoid tumor fistulating to small bowel.
  • [MeSH-major] Fibromatosis, Abdominal / complications. Intestinal Fistula / etiology. Intestine, Small. Peritoneal Neoplasms / complications

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  • (PMID = 25820514.001).
  • [ISSN] 1128-045X
  • [Journal-full-title] Techniques in coloproctology
  • [ISO-abbreviation] Tech Coloproctol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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17. Ikai A, Fujiwara H, Shiozaki A, Okamoto K, Kosuga T, Konishi H, Komatsu S, Ichikawa D, Morimura R, Kuriu Y, Ikoma H, Nakanishi M, Ochiai T, Sakakura C, Otsuji E: [Gastric cancer arising from gastric polyps in gardner syndrome - a case report]. Gan To Kagaku Ryoho; 2014 Nov;41(12):2262-3
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Total resection of the remaining colon with ileostomy was performed for a pelvic desmoid tumor at the age of 40.
  • In addition, resection of a desmoid tumor of the abdominal wall was performed 8 times in the 25 years since the first operation.
  • The pathological diagnosis was 0-IIa, 70 × 44 mm, tub1, m, ly0, v0, n0, PM (-), DM (-), stageIA.

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  • (PMID = 25731489.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
  • [Chemical-registry-number] Polyposis, Gastric
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18. Pinheiro LV, Fagundes JJ, Coy CS, Cabello C, Toro I, Michellino M, Fachina PH, Ward M, Leal RF, Ayrizono Mde L: Multiple desmoid tumors in a patient with Gardner's syndrome - Report of a case. Int J Surg Case Rep; 2014;5(7):370-4
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Multiple desmoid tumors in a patient with Gardner's syndrome - Report of a case.
  • INTRODUCTION: Desmoid tumor (DT) is a common manifestation of Gardner's Syndrome (GS), although it is a rare condition in the general population.
  • DT in patients with GS is usually located in the abdominal wall and/or intra-abdominal cavity.
  • PRESENTATION OF CASE: We report a case of a 32 years-old female patient with familial adenomatous polyposis (FAP), who was already submitted to total colectomy and developed multiple DT, located in the abdominal wall and in the left breast.
  • Wide surgical resections of the left breast and the abdominal wall tumors were performed in separate steps.
  • Polypropylene mesh reconstruction and muscle flaps were needed to cover the defects of the thoracic and abdominal walls.
  • After partial necrosis of the adipose-cutaneous flap in the abdomen that required a new skin graft, she had a satisfactory outcome with complete healing of the surgical incisions.
  • GS patients must be followed up closely, and clinical examination, associated with imaging studies, should be performed to detect any signs of tumor.

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  • [Copyright] Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.
  • (PMID = 24858982.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4064399
  • [Keywords] NOTNLM ; Desmoid tumor / Familial adenomatous polyposis / Gardner's syndrome / Surgical approach
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19. Ye C, Zhang G, Chai Y: A rare desmoid tumor arising from the manubrium. J Cardiothorac Surg; 2015;10:33
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  • [Title] A rare desmoid tumor arising from the manubrium.
  • Desmoid tumors are rare soft tissue tumors derived from fascia and connective tissue of the muscular layers.
  • The abdominal region is the most frequent site of involvement, whereas involvement of sternal manubrium is rare.
  • We report the case of a rare desmoid tumor in the sternal manubrium mimicking radiological and metabolic features of malignant tumor, which was successfully treated by sternal resection and reconstruction with autogenous rib grafts.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Manubrium. Soft Tissue Neoplasms / diagnosis
  • [MeSH-minor] Diagnosis, Differential. Humans. Male. Middle Aged. Ribs / transplantation. Sternotomy / methods. Tomography, X-Ray Computed

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  • [Cites] Plast Reconstr Surg. 2008 May;121(5):353e-355e [18453964.001]
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  • (PMID = 25884938.001).
  • [ISSN] 1749-8090
  • [Journal-full-title] Journal of cardiothoracic surgery
  • [ISO-abbreviation] J Cardiothorac Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4365775
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20. Pacheco Compaña FJ, Alvarez Jorge A, Delgado Sotorrío C: Extra-abdominal desmoid tumor located in the axilla. Arch Plast Surg; 2014 Nov;41(6):780-2
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  • [Title] Extra-abdominal desmoid tumor located in the axilla.

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  • (PMID = 25396198.001).
  • [ISSN] 2234-6163
  • [Journal-full-title] Archives of plastic surgery
  • [ISO-abbreviation] Arch Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4228228
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21. Mullinax JE, Gonzalez RJ: Management of Truncal Sarcoma. Surg Clin North Am; 2016 Oct;96(5):1003-13
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  • The management of truncal sarcoma presents unique challenges to the treating physician for reasons specific to this tumor location.
  • First, the reconstruction options after resection of the abdominal or chest wall require a balance between cosmesis and structural integrity due to the multiplanar forces exerted on this region.
  • [MeSH-major] Disease Management. Sarcoma / therapy

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  • [Copyright] Copyright © 2016 Elsevier Inc. All rights reserved.
  • (PMID = 27542639.001).
  • [ISSN] 1558-3171
  • [Journal-full-title] The Surgical clinics of North America
  • [ISO-abbreviation] Surg. Clin. North Am.
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Desmoid / Liposarcoma / Sentinel node biopsy / Spermatic cord
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22. Campara Z, Spasic A, Aleksic P, Milev B: An Aggressive Retroperitoneal Fibromatosis. Med Arch; 2016 Apr;70(2):154-7
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  • [Title] An Aggressive Retroperitoneal Fibromatosis.
  • INTRODUCTION: Aggressive fibromatosis (AF) is a heterogeneous group of mesenchymal tumors that have locally infiltrative growth and a tendency to relapse.
  • Diagnosis is based on clinical, radiological and histological parameters.
  • A CASE REPORT: We report a case of male patient, aged 35 years, with the retroperitoneal fibromatosis.
  • Computed tomography revealed the tumor mass on the front wall of the bladder with diameter of 70mm with signs of infiltration of the musculature of the anterior abdominal wall.
  • Endoscopic transurethral biopsy showed proliferative lesion binders by type of fibromatosis.
  • The tumor was surgically removed in a classical way.
  • CONCLUSION: The complete tumor resection is the therapeutic choice for the primary tumor as well as for a relapse.

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  • (PMID = 27147794.001).
  • [ISSN] 0350-199X
  • [Journal-full-title] Medical archives (Sarajevo, Bosnia and Herzegovina)
  • [ISO-abbreviation] Med Arch
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Bosnia and Herzegovina
  • [Other-IDs] NLM/ PMC4851536
  • [Keywords] NOTNLM ; aggressive fibromatosis / desmoid / radiation therapy / relapse / surgery
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23. Meshikhes AW, Al-Zahrani H, Ewies T: Laparoscopic excision of abdominal wall desmoid tumor. Asian J Endosc Surg; 2016 Feb;9(1):79-82
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Laparoscopic excision of abdominal wall desmoid tumor.
  • Open surgical resection is the mainstay treatment for desmoid tumors.
  • We report a case of a single, 35-year-old woman who presented with palpable abdominal wall desmoid tumor.
  • The patient had had laparoscopic cholecystectomy 2 years earlier, and the tumor was at the insertion site of the right upper quadrant trocar.
  • The diagnosis was made by a Tru-Cut biopsy at another institution, after the lesion had increased in size and caused increased discomfort.
  • The patient underwent successful laparoscopic resection of the tumor.
  • This report aimed to promote laparoscopic resection of abdominal wall desmoid tumors, whenever feasible, and describe the laparoscopic technique.
  • We believe this is the second case of laparoscopic excision of desmoid tumor reported in the English-language literature.
  • [MeSH-major] Abdominal Neoplasms / surgery. Fibromatosis, Aggressive / surgery. Laparoscopy / methods

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  • [Copyright] © 2016 Japan Society for Endoscopic Surgery, Asia Endosurgery Task Force and John Wiley & Sons Australia, Ltd.
  • (PMID = 26781534.001).
  • [ISSN] 1758-5910
  • [Journal-full-title] Asian journal of endoscopic surgery
  • [ISO-abbreviation] Asian J Endosc Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Desmoid tumor / laparoscopy / surgical resection
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24. Yamabuki T, Suzuoki M, Murakami T, Hirano S: Laparoscopic Resection of a Jejunal Mesenteric Pseudocyst. Case Rep Gastroenterol; 2017 Sep-Dec;11(3):526-530
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  • [Title] Laparoscopic Resection of a Jejunal Mesenteric Pseudocyst.
  • An unusual case of a jejunal mesenteric pseudocyst treated by laparoscopic resection is reported.
  • A 44-year-old woman was admitted to our hospital with intermittent upper abdominal pain and diarrhea.
  • Based on these findings, a gastrointestinal stromal tumor accompanied by hemorrhagic and cystic change, a mesenteric hematoma, or a desmoid tumor was diagnosed.
  • Laparoscopy was performed to obtain an accurate diagnosis.
  • Exploration of the abdominal cavity identified a 4-cm mass originating from the mesentery of the jejunum.
  • The final pathological diagnosis was a mesenteric pseudocyst.

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  • [Keywords] NOTNLM ; Jejunum / Laparoscopic resection / Mesenteric pseudocyst
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25. Howard JH, Pollock RE: Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis. Oncol Ther; 2016;4(1):57-72
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  • [Title] Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis.
  • Desmoid fibromatosis is a rare but locally aggressive tumor comprised of myofibroblasts.
  • These tumors may occur throughout the body, but are commonly found on the abdominal wall and within the intestinal mesentery.
  • Surgical resection with histologically negative margins has been the cornerstone of therapy for this disease, but this paradigm has begun to shift.
  • The decision to use radiation and/or systemic therapies is often based on tumor biology, tumor location, surgical morbidity, and patient preference.
  • Unfortunately, the rarity of this disease has resulted in a scarcity of randomized trials to evaluate any of these therapies emphasizing the need for this disease to be treated at high volume multidisciplinary institutions.

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  • (PMID = 28261640.001).
  • [ISSN] 2366-1070
  • [Journal-full-title] Oncology and therapy
  • [ISO-abbreviation] Oncol Ther
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] New Zealand
  • [Keywords] NOTNLM ; Abdominal desmoid tumor / Abdominal wall desmoid tumor / Desmoid fibromatosis / Desmoid tumor
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26. Mizuno M, Kawaguchi Y, Kawanishi A, Kawashima Y, Maruno A, Ogawa M, Tomioku M, Furukawa D, Nabeshima K, Nakamura K, Hirabayashi K, Mine T: An Intra-Abdominal Desmoid Tumor, Embedded in the Pancreas, Preoperatively Diagnosed as an Extragastric Growing Gastrointestinal Stromal Tumor. Case Rep Oncol; 2017 Jan-Apr;10(1):301-307
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  • [Title] An Intra-Abdominal Desmoid Tumor, Embedded in the Pancreas, Preoperatively Diagnosed as an Extragastric Growing Gastrointestinal Stromal Tumor.
  • A 45-year-old woman was found to have a pancreatic tumor by abdominal ultrasound performed for a medical check-up.
  • Abdominal contrast-enhanced computed tomography showed a hypovascular tumor measuring 30 mm in diameter in the pancreatic tail.
  • An extragastric growing gastrointestinal stromal tumor was thereby diagnosed preoperatively, and surgical resection was planned.
  • The histological diagnosis was an intra-abdominal desmoid tumor.
  • A desmoid tumor is a fibrous soft tissue tumor arising in the fascia and musculoaponeurotic tissues.
  • It usually occurs in the extremities and abdominal wall, and only rarely in the abdominal cavity.
  • We experienced a case with an intra-abdominal desmoid tumor that was histologically diagnosed after laparotomy, which had been preoperatively diagnosed as an extragastric growing gastrointestinal stromal tumor.
  • Although rare, desmoid tumors should be considered in the differential diagnosis of intra-abdominal tumors.

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  • (PMID = 28512414.001).
  • [Journal-full-title] Case reports in oncology
  • [ISO-abbreviation] Case Rep Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Switzerland
  • [Keywords] NOTNLM ; Gastrointestinal stromal tumor / Intra-abdominal desmoid tumor / Pancreas
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27. Havez M, Lippa N, Al-Ammari S, Kind M, Stoeckle E, Italiano A, Gangi A, Hauger O, Cornelis F: Percutaneous image-guided cryoablation in inoperable extra-abdominal desmoid tumors: a study of tolerability and efficacy. Cardiovasc Intervent Radiol; 2014 Dec;37(6):1500-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Percutaneous image-guided cryoablation in inoperable extra-abdominal desmoid tumors: a study of tolerability and efficacy.
  • OBJECTIVE: To determine the tolerability, effectiveness and outcomes of percutaneous image-guided cryoablation on inoperable extra-abdominal desmoid tumors.
  • METHODS: Between 2011 and 2012, 13 patients (mean age 39.3 years, range 15-74) with inoperable extra-abdominal desmoid tumors were consecutively treated with cryoablation (17 tumors treated in 17 procedures), including two patients with Gardner syndrome and nine recurrences after surgery.
  • Disease-free survival (DFS) and local control based on RECIST criteria were calculated on prospective clinical and imaging follow-up until 2013.
  • The local tumor progression rate was 0% at 6, 12, and 24 months.
  • CONCLUSIONS: Despite high rates of partial ablation, percutaneous image-guided cryoablation appears to be safe and effective for local control for patients with inoperable extra-abdominal desmoid tumors.
  • [MeSH-major] Cryosurgery / methods. Fibromatosis, Abdominal / surgery. Gardner Syndrome / surgery. Radiography, Interventional. Ultrasonography, Interventional

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  • (PMID = 24402645.001).
  • [ISSN] 1432-086X
  • [Journal-full-title] Cardiovascular and interventional radiology
  • [ISO-abbreviation] Cardiovasc Intervent Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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28. Salas S, Brulard C, Terrier P, Ranchere-Vince D, Neuville A, Guillou L, Lae M, Leroux A, Verola O, Jean-Emmanuel K, Bonvalot S, Blay JY, Le Cesne A, Aurias A, Coindre JM, Chibon F: Gene Expression Profiling of Desmoid Tumors by cDNA Microarrays and Correlation with Progression-Free Survival. Clin Cancer Res; 2015 Sep 15;21(18):4194-200
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  • [Title] Gene Expression Profiling of Desmoid Tumors by cDNA Microarrays and Correlation with Progression-Free Survival.
  • PURPOSE: Because desmoid tumors exhibit an unpredictable clinical course, translational research is crucial to identify the predictive factors of progression in addition to the clinical parameters.
  • EXPERIMENTAL DESIGN: Gene-expression screening was conducted on 115 available independent untreated primary desmoid tumors using cDNA microarray.
  • [MeSH-major] Abdominal Neoplasms / genetics. Abdominal Neoplasms / pathology. Adenomatous Polyposis Coli / genetics. Adenomatous Polyposis Coli / pathology. Fibromatosis, Aggressive / genetics. Fibromatosis, Aggressive / pathology. Gene Expression Profiling. Oligonucleotide Array Sequence Analysis
  • [MeSH-minor] Adult. Biomarkers, Tumor / metabolism. Blood Proteins / metabolism. DNA, Complementary / metabolism. Disease Progression. Disease-Free Survival. Down-Regulation. Female. Gene Expression Regulation, Neoplastic. Humans. Male. Membrane Proteins / metabolism. Middle Aged. Multivariate Analysis. Neoplasm Recurrence, Local. Predictive Value of Tests. Prognosis. Treatment Outcome

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  • [Copyright] ©2015 American Association for Cancer Research.
  • (PMID = 25878329.001).
  • [ISSN] 1078-0432
  • [Journal-full-title] Clinical cancer research : an official journal of the American Association for Cancer Research
  • [ISO-abbreviation] Clin. Cancer Res.
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / Blood Proteins; 0 / DNA, Complementary; 0 / Membrane Proteins; 0 / STOML2 protein, human; Desmoid disease, hereditary
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29. Verschoor AJ, Cleton-Jansen AM, Wijers-Koster P, Coffin CM, Lazar AJ, Nout RA, Rubin BP, Gelderblom H, Bovée JV: Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor. Am J Surg Pathol; 2015 Dec;39(12):1701-7
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  • [Title] Radiation-induced Sarcomas Occurring in Desmoid-type Fibromatosis Are Not Always Derived From the Primary Tumor.
  • Desmoid-type fibromatosis is a rare, highly infiltrative, locally destructive neoplasm that does not metastasize, but recurs often after primary surgery.
  • It is unclear whether these sarcomas develop from the primary tumor or arise de novo in normal tissue.
  • In 4 tertiary referral centers for sarcoma, 6 cases of desmoid-type fibromatosis that subsequently developed sarcoma after radiotherapy were collected.
  • The DNA sequence of CTNNB1 exon 3 in the desmoid-type fibromatosis and the subsequent postradiation sarcoma was determined.
  • Sarcomas developed 5 to 21 years after the diagnosis of desmoid-type fibromatosis and included 2 osteosarcomas, 2 high-grade undifferentiated pleomorphic sarcomas, 1 fibrosarcoma, and 1 undifferentiated spindle cell sarcoma.
  • Three patients showed a CTNNB1 hotspot mutation (T41A, S45F, or S45N) in both the desmoid-type fibromatosis and the radiation-induced sarcoma.
  • The other 3 patients showed a CTNNB1 mutation in the original desmoid-type fibromatosis (2 with a T41A and 1 with an S45F mutation), which was absent in the sarcoma.
  • In conclusion, postradiation sarcomas that occur in the treatment area of desmoid-type fibromatosis are extremely rare and can arise through malignant transformation of CTNNB1-mutated desmoid fibromatosis cells, but may also originate from CTNNB1 wild-type normal cells lying in the radiation field.
  • [MeSH-major] Abdominal Neoplasms / radiotherapy. Adenomatous Polyposis Coli / radiotherapy. Cell Lineage. Fibromatosis, Aggressive / radiotherapy. Neoplasms, Radiation-Induced / pathology. Sarcoma / pathology
  • [MeSH-minor] Adolescent. Adult. Biomarkers, Tumor / analysis. Biomarkers, Tumor / genetics. Biopsy. Child. DNA Mutational Analysis. Exons. Female. Humans. Immunohistochemistry. Male. Middle Aged. Mutation. Prognosis. Tertiary Care Centers. Time Factors. United States. Young Adult. beta Catenin / genetics

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  • (PMID = 26414222.001).
  • [ISSN] 1532-0979
  • [Journal-full-title] The American journal of surgical pathology
  • [ISO-abbreviation] Am. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / CTNNB1 protein, human; 0 / beta Catenin; Desmoid disease, hereditary
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30. Vicens RA, Patnana M, Le O, Bhosale PR, Sagebiel TL, Menias CO, Balachandran A: Multimodality imaging of common and uncommon peritoneal diseases: a review for radiologists. Abdom Imaging; 2015 Feb;40(2):436-56
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  • Peritoneal disease can be caused by a wide spectrum of pathologies.
  • While peritoneal disease is usually caused by primary or secondary malignancies, benign diseases can occur and mimic malignancies.
  • The uncommon diseases which cause peritoneal disease include desmoid fibromatosis, desmoplastic small round cell tumor, malignant mesothelioma, well-differentiated mesothelioma, multicystic mesothelioma, papillary serous carcinoma, leiomyomatosis, extramedullary hematopoiesis, inflammatory pseudotumor and amyloidosis.
  • [MeSH-major] Magnetic Resonance Imaging. Multimodal Imaging / methods. Peritoneal Diseases / diagnosis. Peritoneal Neoplasms / diagnosis. Positron-Emission Tomography. Tomography, X-Ray Computed
  • [MeSH-minor] Contrast Media. Diagnosis, Differential. Humans. Image Enhancement. Peritoneum / pathology. Peritoneum / radiography. Peritoneum / radionuclide imaging

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  • (PMID = 25139643.001).
  • [ISSN] 1432-0509
  • [Journal-full-title] Abdominal imaging
  • [ISO-abbreviation] Abdom Imaging
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Contrast Media
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31. Mussi CE, Colombo P, Lo Russo C, Kasangian A, Cananzi F, Marrari A, Morenghi E, De Sanctis R, Quagliuolo V: Sporadic desmoid tumors of the abdominal wall: the results of surgery. Tumori; 2016 Dec 01;102(6):582-587
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  • [Title] Sporadic desmoid tumors of the abdominal wall: the results of surgery.
  • PURPOSE: Before the wait-and-see policy became the standard approach in abdominal wall desmoid tumors, surgery was performed on a systematic basis.
  • The abdominal wall is a common site of origin of sporadic desmoids, usually associated with a favorable prognosis.
  • METHODS: Data from 33 patients affected by sporadic desmoid tumors of the abdominal wall (31 primary, 2 recurrent) consecutively treated at our cancer center between January 2000 and September 2013 were retrospectively studied.
  • Prosthetic reconstruction of the abdominal wall was required in 28 patients.
  • CONCLUSIONS: Desmoid tumors of the abdominal wall have a favorable prognosis after surgical resection, which remains a safe and effective treatment.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Abdominal / surgery
  • [MeSH-minor] Adult. Disease Progression. Female. Humans. Male. Middle Aged. Mutation. Neoplasm Recurrence, Local. Postoperative Complications. Prognosis. Proportional Hazards Models. Treatment Outcome. Tumor Burden

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  • (PMID = 27647224.001).
  • [ISSN] 2038-2529
  • [Journal-full-title] Tumori
  • [ISO-abbreviation] Tumori
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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32. Leon MG, Moussa HN, Movahedian M, Viteri OA, Longo M, Sibai BM: A Rapidly Growing Abdominal Mass: Desmoid Tumor in Pregnancy. AJP Rep; 2015 Apr;5(1):e14-7
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  • [Title] A Rapidly Growing Abdominal Mass: Desmoid Tumor in Pregnancy.
  • Background Desmoid tumors are benign soft tissue tumors that locally invade adjacent tissue.
  • Case A giant desmoid tumor arising from the left abdominal wall of a young female patient with rapid growth during pregnancy is described.
  • Decision made by a multidisciplinary team was not to intervene before birth, and abdominal delivery at term was accomplished.
  • Conclusion Desmoid tumors should be part of the differential diagnosis in an abdominal wall tumor of rapid growth during pregnancy.
  • Future studies are needed for better understanding of the pathogenesis, diagnosis, and treatment of desmoid tumors in pregnant women.

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  • (PMID = 26199790.001).
  • [ISSN] 2157-6998
  • [Journal-full-title] AJP reports
  • [ISO-abbreviation] AJP Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4502627
  • [Keywords] NOTNLM ; abdominal wall / desmoid tumor / pregnancy / rapid growth
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33. Tropea S, Mocellin S, Stramare R, Bonavina MG, Rossi CR, Rastrelli M: Desmoid Fibromatosis of the Abdominal Wall: Surgical Resection and Reconstruction with Biological Matrix Egis<sup>®</sup>. Case Rep Oncol; 2017 Jan-Apr;10(1):205-211
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  • [Title] Desmoid Fibromatosis of the Abdominal Wall: Surgical Resection and Reconstruction with Biological Matrix Egis<sup>®</sup>.
  • Desmoid tumor is a rare monoclonal fibroblast proliferation that is regarded as benign.
  • The clinical management of desmoid tumors is very complex and requires a multidisciplinary approach because of the unpredictable disease course.
  • For those cases localized in the anterior abdominal wall, symptomatic and unresponsive to medical treatment, radical resection and reconstruction with a prosthetic device are indicated.
  • We present here a case of desmoid fibromatosis of the left anterolateral abdominal wall with a marked increase of the mass that required a large excision followed by reconstruction with biological matrix.

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  • [Journal-full-title] Case reports in oncology
  • [ISO-abbreviation] Case Rep Oncol
  • [Language] eng
  • [Publication-type] Journal Article
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  • [Keywords] NOTNLM ; Abdominal wall / Acellular dermis / Fibromatosis / Regeneration
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34. He XD, Zhang YB, Wang L, Tian ML, Liu W, Qu Q, Li BL, Hong T, Li NC, Na YQ: Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: Analysis of 114 patients at a single institution. Eur J Surg Oncol; 2015 Aug;41(8):1013-9
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  • [Title] Prognostic factors for the recurrence of sporadic desmoid-type fibromatosis after macroscopically complete resection: Analysis of 114 patients at a single institution.
  • AIMS: Desmoid-type fibromatoses (DFs) are rare soft-tissue neoplasms with frequent local recurrence.
  • In univariate analysis, age, tumor size, tumor site, margin status and presence of lesions at multiple sites had a significant impact on RFS.
  • In multiple analysis, younger age (age<30 vs. age≥50 years: hazard ratio [HR] = 4.96; 95% confidence interval [95% CI], 1.50-16.4; p = 0.009); an extra-abdominal site (extra-abdominal site vs. other sites: HR = 4.08; 95% CI, 1.49-11.2; p = 0.006); larger tumor size (≥8 cm vs. <8 cm: HR = 2.43; 95% CI, 1.15-5.13; p = 0.021); and close or positive margin status (close margin/R1 vs.
  • [MeSH-major] Abdominal Neoplasms / diagnosis. Fibromatosis, Aggressive / diagnosis. Laparotomy / methods. Neoplasm Recurrence, Local / diagnosis. Risk Assessment / methods
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. China / epidemiology. Disease-Free Survival. Female. Follow-Up Studies. Humans. Incidence. Male. Middle Aged. Prognosis. Retrospective Studies. Risk Factors. Survival Rate / trends. Time Factors. Young Adult

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  • [Copyright] Copyright © 2015 Elsevier Ltd. All rights reserved.
  • (PMID = 26005133.001).
  • [ISSN] 1532-2157
  • [Journal-full-title] European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
  • [ISO-abbreviation] Eur J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] England
  • [Keywords] NOTNLM ; Fibromatosis / Recurrence-free survival / Risk factors / Surgery
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35. Gan M, Boothe D, Neklason DW, Samadder NJ, Frandsen J, Keener MB, Lloyd S: Outcomes and complications of radiation therapy in patients with familial adenomatous polyposis. J Gastrointest Oncol; 2017 Aug;8(4):643-649
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  • Treated sites included rectal cancer, desmoid, prostate cancer, breast cancer, melanoma, medulloblastoma, gastric cancer, and glioma.
  • Secondary tumors occurred in two patients: a medulloblastoma was diagnosed in a patient treated for glioma, and a desmoid tumor was diagnosed in a patient treated for rectal cancer.
  • All nine patients treated with intra-abdominal or pelvic RT had prior prophylactic proctocolectomies, yet only one patient experienced grade 3 gastrointestinal toxicity.

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  • (PMID = 28890814.001).
  • [ISSN] 2078-6891
  • [Journal-full-title] Journal of gastrointestinal oncology
  • [ISO-abbreviation] J Gastrointest Oncol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01 CA073992
  • [Publication-type] Journal Article
  • [Publication-country] China
  • [Keywords] NOTNLM ; Familial cancer syndrome / adjuvant treatment / adverse effects / tumorigenesis
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36. Woltsche N, Gilg MM, Fraissler L, Liegl-Atzwanger B, Beham A, Lackner H, Benesch M, Leithner A: Is wide resection obsolete for desmoid tumors in children and adolescents? Evaluation of histological margins, immunohistochemical markers, and review of literature. Pediatr Hematol Oncol; 2015 Feb;32(1):60-9
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  • [Title] Is wide resection obsolete for desmoid tumors in children and adolescents? Evaluation of histological margins, immunohistochemical markers, and review of literature.
  • Desmoid fibromatosis is a benign fibroblastic neoplasm with high recurrence rates predominantly observed in pediatric and adolescent patients.
  • Tumor location, surgical treatment for primary or recurrent tumors, resection margins, medical neo-/adjuvant treatment, time to recurrence as well as immunohistochemical markers (estrogen receptor, ER α and β, progesterone and androgen receptors, somatostatin, Ki-67, c-kit, platelet-derived growth factor receptors, PDGFRs, α and β, β-catenin) were evaluated.
  • The mean age at diagnosis was 6.6 years, with a mean follow-up of 114 months.
  • No correlation between positive immunohistochemical markers and tumor recurrences was detectable.
  • [MeSH-major] Abdominal Neoplasms. Adenomatous Polyposis Coli. Biomarkers, Tumor / metabolism. Fibromatosis, Aggressive. Neoplasm Recurrence, Local

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  • (PMID = 25264623.001).
  • [ISSN] 1521-0669
  • [Journal-full-title] Pediatric hematology and oncology
  • [ISO-abbreviation] Pediatr Hematol Oncol
  • [Language] eng
  • [Publication-type] Evaluation Studies; Journal Article; Review
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; Desmoid disease, hereditary
  • [Keywords] NOTNLM ; aggressive fibromatosis in children and adolescents / immunohistochemistry / recurrence / type of resection
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37. Cates JM: Prognostic factors for second recurrence after surgical resection of recurrent desmoid-type fibromatosis. Pathol Oncol Res; 2015 Sep;21(4):1085-90
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  • [Title] Prognostic factors for second recurrence after surgical resection of recurrent desmoid-type fibromatosis.
  • The optimal management of recurrent desmoid-type fibromatosis is undefined.
  • This study was performed to determine what factors, if any, predict second recurrence after surgical resection of recurrent desmoid tumors.
  • Of 41 patients with recurrent desmoid-type fibromatosis, 29 underwent surgical resection and 8 were followed by observation.
  • Clinicopathologic features were assessed as prognostic factors for second recurrence after surgical resection of recurrent desmoid tumors by Cox proportional hazards regression.
  • Nine of 29 patients who underwent surgical resection of recurrent desmoid tumor developed a second recurrence.
  • Larger size of recurrent tumor was associated with increased risk of second recurrence (hazard ratio, 1.09; P = 0.006).
  • Treatment of the primary tumor with adjuvant radiation therapy also increased risk of re-recurrence (3.41; P = 0.032).
  • Second recurrence of desmoid-type fibromatosis after surgical resection is, much like recurrence of primary desmoid tumor, difficult to predict with current prognostic indicators.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Abdominal / surgery. Neoplasm Recurrence, Local / pathology. Neoplasm Recurrence, Local / surgery
  • [MeSH-minor] Adult. Chemotherapy, Adjuvant / methods. Disease Progression. Female. Humans. Male. Prognosis

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  • (PMID = 25916970.001).
  • [ISSN] 1532-2807
  • [Journal-full-title] Pathology oncology research : POR
  • [ISO-abbreviation] Pathol. Oncol. Res.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
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38. Palladino E, Nsenda J, Siboni R, Lechner C: A giant mesenteric desmoid tumor revealed by acute pulmonary embolism due to compression of the inferior vena cava. Am J Case Rep; 2014;15:374-7
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  • [Title] A giant mesenteric desmoid tumor revealed by acute pulmonary embolism due to compression of the inferior vena cava.
  • FINAL DIAGNOSIS: Mesenteric desmoid tumor.
  • OBJECTIVE: Rare disease.
  • BACKGROUND: Intra-abdominal fibromatosis is a benign rare tumor of fibrous origin with a significant potential for local invasion and no ability to metastasize, but it can recur.
  • The etiology of desmoid tumors is unknown.
  • Abdominal computerized tomography revealed a mesenterial giant mass with compression of the inferior vena cava (IVC).
  • A biopsy of the mass, confirming aggressive fibromatosis.
  • A laparotomy was performed, which revealed a massive growth occupying the abdomen and attached to the previous ileocolic anastomosis.
  • CONCLUSIONS: This report underlines the potential of imaging investigations of abdomen and vena cava if pulmonary embolism is suspected, especially when there is no evidence of peripheral venous thrombosis or other predisposing factors.
  • Unfortunately, data on the surgical management of desmoid tumor is scarce.
  • [MeSH-major] Fibromatosis, Aggressive / complications. Mesentery. Peritoneal Neoplasms / complications. Pulmonary Embolism / etiology. Vena Cava, Inferior
  • [MeSH-minor] Acute Disease. Aged. Angiography. Biopsy. Constriction, Pathologic / complications. Constriction, Pathologic / diagnosis. Diagnosis, Differential. Fibrinolytic Agents / therapeutic use. Humans. Laparotomy. Male. Thrombolytic Therapy. Tomography, X-Ray Computed

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  • (PMID = 25180474.001).
  • [ISSN] 1941-5923
  • [Journal-full-title] The American journal of case reports
  • [ISO-abbreviation] Am J Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Fibrinolytic Agents
  • [Other-IDs] NLM/ PMC4159246
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39. Efthimiopoulos GA, Chatzifotiou D, Drogouti M, Zafiriou G: Primary asymptomatic desmoid tumor of the mesentery. Am J Case Rep; 2015;16:160-3
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  • [Title] Primary asymptomatic desmoid tumor of the mesentery.
  • BACKGROUND: Desmoid-type fibromatosis (DF) is a rare entity that predominantly involves the extremities, the trunk, and the abdominal cavity.
  • It is a non-metastasizing, sporadic mesenchymal tumor with high tendency to recurrence and often is categorized as low-grade sarcoma.
  • CASE REPORT: We present here an extremely rare case of a mesenteric desmoid tumor (DT).
  • A 40-year-old man presented to our clinic with a mass in the right-lower quadrant of the abdomen, which he incidentally palpated.
  • A computerized tomography (CT) scan of the abdomen showed a mass between the loops of small intestine.
  • No adjuvant treatment was applied and the patient was free of disease after a 6-month follow-up.
  • CONCLUSIONS: Intra-abdominal DF is a rare pathology which should be differentiated while exploring abdominal tumors.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Fibromatosis, Aggressive / surgery. Mesentery. Peritoneal Neoplasms / diagnosis. Peritoneal Neoplasms / surgery

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  • (PMID = 25782060.001).
  • [ISSN] 1941-5923
  • [Journal-full-title] The American journal of case reports
  • [ISO-abbreviation] Am J Case Rep
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4371711
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40. Sugrue JJ, Cohen SB, Marshall RM, Riker AI: Palliative Resection of a Giant Mesenteric Desmoid Tumor. Ochsner J; 2015;15(4):468-72
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  • [Title] Palliative Resection of a Giant Mesenteric Desmoid Tumor.
  • BACKGROUND: Desmoid tumors are relatively uncommon tumors, and those occurring sporadically and in an intraabdominal location are especially rare.
  • Although desmoid tumors have a benign histologic appearance and lack the ability to metastasize, they can invade locally, often aggressively, grow to large sizes, and recur repeatedly.
  • CASE REPORT: We present the case of a symptomatic, giant mesenteric desmoid tumor discovered incidentally during workup for the patient's previous history of lung cancer.
  • The patient elected to undergo palliative resection of the tumor because of persistent and unrelenting abdominal pain.
  • CONCLUSION: Because of the rarity of the disease, no clear evidence-based guidelines exist for the treatment of sporadic mesenteric desmoid tumors.

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  • (PMID = 26730236.001).
  • [ISSN] 1524-5012
  • [Journal-full-title] The Ochsner journal
  • [ISO-abbreviation] Ochsner J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4679313
  • [Keywords] NOTNLM ; Adenomatous polyposis coli / fibromatosis–abdominal / mesentery / neoplasms–fibrous tissue
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41. Kobayashi H, Sugihara K: Intra-abdominal desmoid tumor after resection for gastrointestinal stromal tumor of the small intestine: case report. Jpn J Clin Oncol; 2014 Oct;44(10):982-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Intra-abdominal desmoid tumor after resection for gastrointestinal stromal tumor of the small intestine: case report.
  • Both gastrointestinal stromal tumor and desmoid tumor are rare.
  • The case of a 56-year-old male with a desmoid tumor 1 year after surgical removal of a gastrointestinal stromal tumor near the ligament of Treitz is described.
  • The nodule was considered to be a recurrent tumor of gastrointestinal stromal tumor, and a wedge resection of the duodenum including the tumor was done.
  • Histopathological examination by immunohistochemical staining revealed that it was a desmoid tumor.
  • It would be useful to be aware of the possibility of desmoid tumor after removal of gastrointestinal stromal tumor.
  • [MeSH-major] Antineoplastic Agents / therapeutic use. Benzamides / therapeutic use. Fibromatosis, Abdominal / diagnosis. Fibromatosis, Aggressive / diagnosis. Gastrointestinal Stromal Tumors / surgery. Intestine, Small / surgery. Piperazines / therapeutic use. Pyrimidines / therapeutic use
  • [MeSH-minor] Chemotherapy, Adjuvant. Humans. Imatinib Mesylate. Male. Middle Aged. Neoplasm Recurrence, Local / diagnosis. Rare Diseases

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  • [Copyright] © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.
  • (PMID = 25145379.001).
  • [ISSN] 1465-3621
  • [Journal-full-title] Japanese journal of clinical oncology
  • [ISO-abbreviation] Jpn. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Benzamides; 0 / Piperazines; 0 / Pyrimidines; 8A1O1M485B / Imatinib Mesylate
  • [Keywords] NOTNLM ; desmoid tumor / gastrointestinal stromal tumor
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42. Bolzon S, Vagliasindi A, Zanzi F, Negri M, Guerrini GP, Rossi C, Soliani P: Abdominal wall desmoid tumors: A proposal for US-guided resection. Int J Surg Case Rep; 2015;9:19-22
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abdominal wall desmoid tumors: A proposal for US-guided resection.
  • BACKGROUND: Desmoid tumors (DTs) is a benign tumor with high tendency to infiltrative evolution and recurrence.
  • Nowadays, in abdominal localization, the standard approach is surgery with R0 condition.
  • METHODS: We perform an abdominal wall desmoid resection using ultrasound guide.
  • This approach allows good oncological results and better managing abdominal wall post-resection defect.

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  • [Copyright] Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.
  • (PMID = 25706804.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Other-IDs] NLM/ PMC4392329
  • [Keywords] NOTNLM ; Abdominal wall / Desmoid tumor / Oncological safety / Tissue sparing / Ultrasound
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43. Maher J, Smith DA, Parker WL: Desmoid tumor of the hand: a case report. Ann Plast Surg; 2014 Oct;73(4):390-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Desmoid tumor of the hand: a case report.
  • SUMMARY: Extra-abdominal desmoid tumors are extremely rare in the hand.
  • We describe the first case of a desmoid tumor originating from the extensor mechanism of a digit and discuss our treatment approach.
  • In addition, a literature review performed shows a male predominance of desmoid tumors in the hand in the 30- to 50-year-old age group.
  • [MeSH-major] Fibromatosis, Aggressive / pathology. Fingers / pathology. Soft Tissue Neoplasms / pathology

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  • (PMID = 23657047.001).
  • [ISSN] 1536-3708
  • [Journal-full-title] Annals of plastic surgery
  • [ISO-abbreviation] Ann Plast Surg
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] United States
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44. Couto Netto SD, Teixeira F Jr, Menegozzo CAM, Albertini A, Akaishi EH, Utiyama EM: Abdominal wall reconstruction after desmoid type fibromatosis radical resection: Case series from a single institution and review of the literature. Int J Surg Case Rep; 2017;33:167-172
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  • [Title] Abdominal wall reconstruction after desmoid type fibromatosis radical resection: Case series from a single institution and review of the literature.
  • BACKGROUND: Abdominal wall desmoid type fibromatosis management has been changing over recent years, from an aggressive approach towards a more conservative one.
  • When radical resection is indicated, the surgical team faces the challenge of abdominal wall reconstruction, for which optimal technique is still debated.
  • The present study reports the experience from a single center with abdominal closures after desmoid type fibromatosis resection.
  • MATERIAL AND METHODS: Retrospective analysis of patients who underwent abdominal wall closure after sporadic abdominal desmoid type fibromatosis radical resection from 1982 to 2013.
  • RESULTS: Twenty-seven patients were included, mean tumor diameter was 10 + 5.3 cm, and the main choice of abdominal wall reconstruction was midline closure with anterior rectus sheath relaxing incisions and polypropylene onlay mesh (74% of the cases).
  • Mean follow-up was 5 years and 89% remained disease-free.
  • CONCLUSION: High midline fascial closure rate can be achieved after resection of abdominal wall desmoid tumor using relaxing incisions and mesh, with low complication rate.

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  • [Copyright] Copyright © 2017 The Author(s). Published by Elsevier Ltd.. All rights reserved.
  • (PMID = 28327422.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Abdominal wall reconstruction / Case series / Desmoid resection / Desmoid type fibromatosis / Surgical technique
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45. Sinukumar S, Gomes RM, Kumar RK, Desouza A, Saklani A: Sporadic giant mesenteric fibromatosis. Indian J Surg Oncol; 2014 Sep;5(3):242-5
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Sporadic giant mesenteric fibromatosis.
  • Mesenteric fibromatosis is an uncommon tumour which is locally aggressive without any metastatic potential and can occur as a sporadic event or in association with familial adenomatous polyposis syndrome.
  • Giant mesenteric fibromatosis is very rare and is a diagnostic and therapeutic challenge.
  • This is a case report of a rare presentation of deep fibromatosis as a sporadic giant intrabdominal mesenteric tumour in a 29 year old male managed by surgical excision and definitive diagnosis made on the basis of immunohistochemical findings.

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  • (PMID = 25419076.001).
  • [ISSN] 0975-7651
  • [Journal-full-title] Indian journal of surgical oncology
  • [ISO-abbreviation] Indian J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4235857
  • [Keywords] NOTNLM ; Desmoid tumors / Familial adenomatous polyposis / Mesenteric fibromatosis
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46. Li J, Le H, Chai W, Zhou Y, Jin L, Liu T, Zhang K: Duodenum-derived fibromatosis that invaded the muscular layer of intestinal wall: A rare case report. Medicine (Baltimore); 2017 Aug;96(31):e7684
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Duodenum-derived fibromatosis that invaded the muscular layer of intestinal wall: A rare case report.
  • RATIONALE: Intraabdominal fibromatosis is a rare benign tumor that often affects the mesentery or retroperitoneum, and can infiltrate adjacent organs.
  • However, it is rare for fibromatosis to arise from the small intestinal wall.
  • PATIENT CONCERNS: A 27-year-old female with a tangible abdominal tumor is described.
  • DIAGNOSES: The computed tomography (CT) scan revealed a 7.5 cm, small intestine-associated tumor in the right abdomen.
  • INTERVENTIONS: The patient received tumor resection and intestinal anastomosis.
  • OUTCOMES: Further pathological examination confirmed the tumor as a duodenal fibromatosis that infiltrated the intestinal wall.
  • To the best of our knowledge, this is the first report of a duodenum-derived fibromatosis that invaded the muscular layer of the intestine.
  • LESSONS: Our study demonstrated that an unexplained abdominal mass should be noteworthy and properly treated.
  • [MeSH-major] Duodenal Neoplasms / diagnostic imaging. Duodenal Neoplasms / pathology. Fibromatosis, Abdominal / diagnostic imaging. Fibromatosis, Abdominal / pathology
  • [MeSH-minor] Adult. Diagnosis, Differential. Female. Humans. Muscle, Smooth. Neoplasm Invasiveness. Tomography, X-Ray Computed

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  • (PMID = 28767596.001).
  • [ISSN] 1536-5964
  • [Journal-full-title] Medicine
  • [ISO-abbreviation] Medicine (Baltimore)
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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47. Kuwahara H, Salo J, Tukiainen E: Diaphragm reconstruction combined with thoraco-abdominal wall reconstruction after tumor resection. J Plast Surg Hand Surg; 2017 Aug 31;:1-6
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Diaphragm reconstruction combined with thoraco-abdominal wall reconstruction after tumor resection.
  • BACKGROUND: Thoraco-abdominal wall resection including diaphragm resection results in a challenging surgical defect.
  • The aim of this study was to describe our methods of diaphragm and thoraco-abdominal wall reconstruction after combined resection of these anatomical structures.
  • RESULTS: Indications for resection were primary sarcoma (n = 14), cancer metastasis (n = 4), desmoid tumor (n = 2), and solitary fibrous tumor (n = 1).
  • CONCLUSIONS: We have described our surgical methods for the resection of tumors of the chest or abdominal wall, including our method of distal diaphragm resection with wide or clear surgical margins.
  • There were no cases of paradoxical movement of the chest or of diaphragm or thoraco-abdominal hernia.

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  • (PMID = 28857656.001).
  • [ISSN] 2000-6764
  • [Journal-full-title] Journal of plastic surgery and hand surgery
  • [ISO-abbreviation] J Plast Surg Hand Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Sweden
  • [Keywords] NOTNLM ; Chest wall / diaphragm / mesh / reconstruction / sandwich mesh method
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48. Nakai M, Tazawa T, Wajima N, Muroya T, Mikami K, Hakamada K: [A Case of Mesenteric Fibromatosis after Robot-Assisted Total Gastrectomy for Gastric Cancer]. Gan To Kagaku Ryoho; 2016 Nov;43(12):1839-1841
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] [A Case of Mesenteric Fibromatosis after Robot-Assisted Total Gastrectomy for Gastric Cancer].
  • Thirty-four months later, he was admitted to another hospital because of abdominal discomfort.
  • Computed tomography scans showed a giant solid mass approximately 13 cm in diameter in the lower abdomen.
  • We performed a resection of the tumor; operative findings showed a giant solid tumor, without adhesion, in the mesentery of the jejunum.
  • The tumor did not involve other parts of the small intestine.
  • The resected tumor had a smooth surface with an elastic hard consistency.
  • Pathological examination revealed that the tumor was immunohistochemically positive for a-SMA and b-catenin and negative for S-100, CD34, and c-kit.
  • The tumor was diagnosed as a mesenteric fibromatosis.
  • Mesenteric fibromatosis is a very rare condition and has been reported in association with Gardner's syndrome, abdominal traumas such as surgery and injury, and with pregnancy.
  • This report describes a case of mesenteric fibromatosis after robotassisted laparoscopic surgery.
  • [MeSH-major] Fibromatosis, Abdominal. Mesentery / pathology. Peritoneal Neoplasms / pathology. Stomach Neoplasms

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  • (PMID = 28133149.001).
  • [ISSN] 0385-0684
  • [Journal-full-title] Gan to kagaku ryoho. Cancer & chemotherapy
  • [ISO-abbreviation] Gan To Kagaku Ryoho
  • [Language] jpn
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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49. D M, Ghalige HS, R S, Sharma MB, Singh TS: Mesenteric fibromatosis (desmoid tumour) - a rare case report. J Clin Diagn Res; 2014 Nov;8(11):ND01-2
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric fibromatosis (desmoid tumour) - a rare case report.
  • Mesenteric Fibromatosis (MF) is a proliferative fibroblastic lesion of small intestinal mesentery.
  • It constitutes 8% of all desmoid tumours, which represent 0.03% of all neoplasm.
  • The presenting features of MF are asymptomatic abdominal mass, abdominal discomfort or pain, bowel or ureteral obstruction, intestinal perforation, fistula, functional impairment of ileoanal anastomosis following colectomy in FAP cases.
  • End to end anastomosis was done and specimen was sent for histopathology which confirmed the diagnosis of MF.
  • Considering the rarity of this tumour and difficulties in diagnostic and therapeutic ambit, we believe it is justified to describe this case which came to our observation.

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  • (PMID = 25584260.001).
  • [ISSN] 2249-782X
  • [Journal-full-title] Journal of clinical and diagnostic research : JCDR
  • [ISO-abbreviation] J Clin Diagn Res
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] India
  • [Other-IDs] NLM/ PMC4290279
  • [Keywords] NOTNLM ; Desmoid tumour / Gardner’s syndrome / Mesenteric fibromatosis
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50. Huang K, Stuart H, Lyapichev K, Rosenberg AE, Livingstone AS: Mesenteric desmoid tumour presenting with recurrent abdominal abscess and duodenal fistula: A case report and review of literature. Int J Surg Case Rep; 2017;37:119-123
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Mesenteric desmoid tumour presenting with recurrent abdominal abscess and duodenal fistula: A case report and review of literature.
  • INTRODUCTION: Desmoid tumors are locally destructive but histologically benign.
  • PRESENTATION OF THE CASE: A 36-year-old male was admitted for abdominal pain and fever.
  • A CT scan showed fluid collections and air within a mesenteric mass.
  • The pathology suggested a desmoid tumor.
  • His fever and abdominal pain persisted.
  • The patient underwent an en bloc resection of the tumor including a portion of the wall of the third part of the duodenum.
  • The final pathology confirmed a desmoid tumor with a fistula track to the duodenum.
  • The patient had a re-laparotomy on POD2 for intra-abdominal bleeding but was discharged without further events on POD7.
  • DISCUSSION: Desmoid tumors are rarely complicated by abscess formation or fistulization.
  • The management of intra-abdominal desmoids in this setting is challenging, as patients are often symptomatic and unresponsive to medical management.
  • Percutaneous drainage and antibiotics are often initiated as first-line treatment, followed by surgery or medical therapy after evaluation of resectability and tumor stage.
  • CONCLUSION: Rare complications can arise with intra-abdominal desmoid tumors.

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  • [Copyright] Published by Elsevier Ltd.
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  • (PMID = 28666150.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Abscess formation / Case report / Desmoid tumor / Fistula / Treatment
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51. Oh C, Hammoudeh ZS, Carlsen BT: Desmoid tumor following abdominally-based free flap breast reconstruction. Gland Surg; 2017 Feb;6(1):89-92
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  • [Title] Desmoid tumor following abdominally-based free flap breast reconstruction.
  • Desmoid tumors are fibroblastic connective tissue tumors that most commonly develop within the anterior abdominal wall.
  • The etiology of desmoid tumors has not been well defined; however, hereditary, hormonal, traumatic, and surgery-related causes have been implicated.
  • Desmoid tumors are believed to arise from musculoaponeurotic structures.
  • Several reports of desmoid tumors arising in the vicinity of the fibrous capsule of a breast implant have been described, but to date, the authors are not aware of any published cases following autologous breast reconstruction.
  • This report describes a desmoid tumor developing after a muscle-sparing free transverse rectus abdominis musculocutaneous (TRAM) flap for breast reconstruction and subsequent surgical management.

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  • (PMID = 28210557.001).
  • [ISSN] 2227-684X
  • [Journal-full-title] Gland surgery
  • [ISO-abbreviation] Gland Surg
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] China (Republic : 1949- )
  • [Keywords] NOTNLM ; Desmoid / breast reconstruction / fibromatosis
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52. Zreik RT, Fritchie KJ: Morphologic Spectrum of Desmoid-Type Fibromatosis. Am J Clin Pathol; 2016 Mar;145(3):332-40
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Morphologic Spectrum of Desmoid-Type Fibromatosis.
  • OBJECTIVES: Desmoid-type fibromatosis is a locally aggressive neoplasm composed of long sweeping fascicles of bland fibroblasts/myofibroblasts.
  • Tumors with classic features are easy to identify, but the morphologic spectrum of this entity spans beyond the conventional histologic pattern.
  • Since sampling of an unrecognized histologic variant may lead to misdiagnosis, especially on small needle biopsy specimens, we sought to fully characterize the morphologic spectrum of this entity.
  • METHODS: We examined 165 cases of desmoid-type fibromatosis and catalogued the morphologic patterns and percentage of those patterns identified in each case.
  • RESULTS: Seven morphologic patterns were identified, including conventional, hyalinized/hypocellular, staghorn vessel, myxoid, keloidal, nodular fasciitis-like, and hypercellular.
  • The greatest morphologic variability was seen in the intra-abdominal lesions, with these tumors having a significantly higher percentage of the keloidal and staghorn patterns compared with extra-abdominal and abdominal wall sites.
  • No significant correlation between patient outcome (recurrence) and presence of variant morphologic pattern was observed (P = .549).
  • CONCLUSIONS: The morphologic spectrum of desmoid-type fibromatosis is deceptively broad, and awareness of the variety of histologic patterns is critical for accurate diagnosis.
  • [MeSH-major] Fibromatosis, Abdominal / pathology. Fibromatosis, Aggressive / pathology. Soft Tissue Neoplasms / pathology
  • [MeSH-minor] Adolescent. Adult. Aged. Aged, 80 and over. Child. Child, Preschool. Cohort Studies. Education, Medical, Continuing. Female. Fibroblasts / pathology. Humans. Male. Middle Aged. Myofibroblasts / pathology. Neoplasm Invasiveness. Neoplasm Recurrence, Local / classification. Neoplasm Recurrence, Local / diagnosis. Neoplasm Recurrence, Local / pathology. Retrospective Studies. Young Adult

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  • [Copyright] © American Society for Clinical Pathology, 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
  • (PMID = 27124915.001).
  • [ISSN] 1943-7722
  • [Journal-full-title] American journal of clinical pathology
  • [ISO-abbreviation] Am. J. Clin. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Aggressive fibromatosis / Deep fibromatosis / Desmoid tumor / Desmoid-type fibromatosis / Morphology
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53. Lou L, Teng J, Qi H, Ban Y: Sonographic appearances of desmoid tumors. J Ultrasound Med; 2014 Aug;33(8):1519-25
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  • [Title] Sonographic appearances of desmoid tumors.
  • The medical records of 16 patients (9 female and 7 male; age range, 5-66 years) with 24 lesions that had a histologic diagnosis of desmoid tumors were reviewed at our institution.
  • Six cases were extra-abdominal, 4 intra-abdominal, and 6 in the abdominal wall.
  • Sonography can show a desmoid tumor's site, size, contour, margin, echogenicity, homogeneity, vascularity, and resistive index value in detail.
  • [MeSH-major] Abdominal Neoplasms / ultrasonography. Fibromatosis, Aggressive / ultrasonography. Muscle Neoplasms / ultrasonography
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Child, Preschool. Diagnosis, Differential. Female. Humans. Male. Middle Aged. Retrospective Studies. Ultrasonography, Doppler, Color / methods. Ultrasonography, Doppler, Pulsed / methods. Young Adult

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  • [Copyright] © 2014 by the American Institute of Ultrasound in Medicine.
  • (PMID = 25063419.001).
  • [ISSN] 1550-9613
  • [Journal-full-title] Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
  • [ISO-abbreviation] J Ultrasound Med
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Keywords] NOTNLM ; aggressive fibromatosis / color Doppler sonography / desmoid tumor / musculoskeletal ultrasound / sonography / spectral Doppler sonography
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54. Wongmaneerung P, Somwangprasert A, Watcharachan K, Ditsatham C: Bilateral desmoid tumor of the breast: case seriesand literature review. Int Med Case Rep J; 2016;9:247-51
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  • [Title] Bilateral desmoid tumor of the breast: case seriesand literature review.
  • BACKGROUND: Desmoid tumor of the breast is very rare and locally aggressive but has no distant metastasis.
  • Two cases of bilateral desmoid tumor of the breast are reported.
  • The clinical presentation, diagnosis, imaging, treatment, and follow-up outcomes of recurrence as well as a brief literature review are provided.
  • She underwent a bilateral excisional biopsy under ultrasound mark with the pathology result of extra-abdominal desmoid tumor in both breasts.
  • She remained tumor free after 7-year follow-up.
  • The pathology result was an extra-abdominal desmoid tumor.
  • The tumor has not recurred after 1-year follow-up.
  • Pathology results are helpful in making a definitive diagnosis.
  • Given that the desmoid tumor is locally aggressive, a local excision with clear margins is recommended.

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  • (PMID = 27578999.001).
  • [ISSN] 1179-142X
  • [Journal-full-title] International medical case reports journal
  • [ISO-abbreviation] Int Med Case Rep J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] New Zealand
  • [Other-IDs] NLM/ PMC5001652
  • [Keywords] NOTNLM ; breast fibromatosis / extraabdominal desmoid tumor / rare breast disease
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55. Togral G, Yildizgoren MT, Arikan M, Gungor S: Destructive invasion of the clavicle by desmoid tumor: a case report. Pan Afr Med J; 2014;19:383
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  • [Title] Destructive invasion of the clavicle by desmoid tumor: a case report.
  • Desmoid tumors are rare, soft-tissue neoplasms that do not metastasize, but exhibit aggressive growth and local invasion.
  • They originate most frequently from abdominal fascial structures, although they can also appear at extra-abdominal sites.
  • The most common extra-abdominal locations include the shoulder, chest wall, back, thigh, and head and neck.
  • In children, desmoid tumors are more infiltrative, having a tendency towards osseous involvement more frequently than in adult patients.
  • We report acase of a supraspinatus muscle desmoid tumor in a female patient with clavicle destruction.

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  • (PMID = 25995779.001).
  • [ISSN] 1937-8688
  • [Journal-full-title] The Pan African medical journal
  • [ISO-abbreviation] Pan Afr Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Uganda
  • [Other-IDs] NLM/ PMC4430038
  • [Keywords] NOTNLM ; Desmoid tumor / clavicle / shoulder
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56. Hanna D, Magarakis M, Twaddell WS, Alexander HR, Kesmodel SB: Rapid progression of a pregnancy-associated intra-abdominal desmoid tumor in the post-partum period: A case report. Int J Surg Case Rep; 2016;29:30-33
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  • [Title] Rapid progression of a pregnancy-associated intra-abdominal desmoid tumor in the post-partum period: A case report.
  • INTRODUCTION: The clinical behavior of desmoid tumors can be unpredictable, particularly when they arise in the ante-partum or post-partum period.
  • We present a case of an intra-abdominal desmoid tumor that was identified in the ante-partum period, progressed rapidly in the post-partum period, and was subsequently resected.
  • PRESENTATION OF CASE: The patient is a 19 year-old female who was found to have a 12cm intra-abdominal mass on a fetal assessment ultrasound.
  • The patient was transferred to our institution after an exploratory laparotomy revealed a large intra-abdominal mass emanating from the small bowel mesentery.
  • The 30cm×24cm×16cm mass was successfully resected with negative margins, and the pathologic diagnosis of desmoid tumor was confirmed.
  • DISCUSSION: The majority of pregnancy-associated desmoid tumors are in the abdominal wall, arising from the rectus abdominus muscle or from previous Cesarean section scars.
  • Close follow-up is important so that rapid tumor progression, which may lead to unresectability, can be identified and managed appropriately.
  • CONCLUSION: A patient with a rare case of a giant pregnancy-associated, intra-abdominal desmoid tumor that rapidly progressed in the post-partum period and was successfully treated with surgical resection with negative margins.

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  • [Copyright] Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
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  • (PMID = 27810608.001).
  • [ISSN] 2210-2612
  • [Journal-full-title] International journal of surgery case reports
  • [ISO-abbreviation] Int J Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Desmoid rapid progression / Intra-abdominal desmoid tumor / Post-partum desmoid / Pregnancy-associated desmoid / Soft tissue tumor
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57. Li Destri G, Ferraro MJ, Calabrini M, Pennisi M, Magro G: Desmoid-type fibromatosis of the mesentery: report of a sporadic case with emphasis on differential diagnostic problems. Case Rep Med; 2014;2014:850180
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  • [Title] Desmoid-type fibromatosis of the mesentery: report of a sporadic case with emphasis on differential diagnostic problems.
  • Desmoid-type fibromatosis is a rare mesenchymal neoplasm with local aggressiveness.
  • The incidence of desmoid-type fibromatosis is 2-5/million/year with intra-abdominal fibromatosis, such as that which is reported in this clinical case, occurring only in 12-18% of cases.
  • After having analyzed the pathogenetic hypotheses of desmoid-type fibromatosis, the authors point out that the diagnosis of this disease, especially in the intra-abdominal form, is often late, specifically when highly demolitive interventions are needed or when the limits of radical surgery have been exceeded.
  • In the clinical case reported, the tumor was infiltrating both ileus and sigma.
  • The authors consider the differential diagnosis of desmoid-type fibromatosis, especially with GISTs, with regard to both the radiological preoperative diagnostic and histological studies on the surgical specimen.
  • Radical surgical excision is not always, for this disease, a sign of healing; in fact, even when the resection margins are negative, the incidence of recurrence is between 13 and 68%.
  • The average time of recurrence is between 15 and 24 months; in this case report, the patient, who has not been subjected to complementary therapies, is tumor-free for over 30 months since surgery; his prognosis may be satisfactory if we consider the negativity of resection margins, which in any case remains the most important prognostic factor.

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  • (PMID = 25349618.001).
  • [ISSN] 1687-9627
  • [Journal-full-title] Case reports in medicine
  • [ISO-abbreviation] Case Rep Med
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC4198783
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58. Jung WB, Kim CW, Kim JC: Clinical characteristics and adequate treatment of familial adenomatous polyposis combined with desmoid tumors. Cancer Res Treat; 2014 Oct;46(4):366-73
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  • [Title] Clinical characteristics and adequate treatment of familial adenomatous polyposis combined with desmoid tumors.
  • PURPOSE: The objective of this study was to examine the clincopathologic characteristics and outcomes of familial adenomatous polyposis (FAP) patients with and without desmoid tumors (DTs), including the risk factors for progression of FAP-related DTs.
  • Seventeen of these had intra-abdominal DTs and one had intra- and extra-abdominal DTs.
  • Two patients in the curative resection group and two patients in the palliative group had progressed to tumor growth by the follow-up (p=0.800).
  • In univariate analysis, DT diagnosis before or simultaneously with FAP diagnosis (DTs unrelated to surgical trauma) was a significant risk factor for tumor progression at final follow-up.

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  • (PMID = 25152189.001).
  • [ISSN] 1598-2998
  • [Journal-full-title] Cancer research and treatment : official journal of Korean Cancer Association
  • [ISO-abbreviation] Cancer Res Treat
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4206065
  • [Keywords] NOTNLM ; Aggressive fibromatosis / Familial adenomatous polyposis / Risk factors
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59. Koo GW, Chung SJ, Kwak JH, Oh CK, Park DW, Kwak HJ, Moon JY, Kim SH, Sohn JW, Yoon HJ, Shin DH, Park SS, Oh YH, Pyo JY, Kim TH: Intrathoracic Desmoid Tumor Presenting as Multiple Lung Nodules 13 Years after Previous Resection of Abdominal Wall Desmoid Tumor. Tuberc Respir Dis (Seoul); 2015 Jul;78(3):267-71
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  • [Title] Intrathoracic Desmoid Tumor Presenting as Multiple Lung Nodules 13 Years after Previous Resection of Abdominal Wall Desmoid Tumor.
  • Desmoid tumors are rare soft tissue tumors considered to have locally infiltrative features without distant metastasis until now.
  • Although they are most commonly intraabdominal, very few cases have extra-abdominal locations.
  • The origin of intrathoracic desmoid tumors is predominantly the chest wall with occasional involvement of pleura.
  • True intrathoracic primary desmoid tumors with no involvement of the chest wall or pleura are extremely rare.
  • We recently experienced a case of true intrathoracic desmoid tumor presenting as multiple lung nodules at 13 years after resection of a previous intraabdominal desmoid tumor.

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  • (PMID = 26175783.001).
  • [ISSN] 1738-3536
  • [Journal-full-title] Tuberculosis and respiratory diseases
  • [ISO-abbreviation] Tuberc Respir Dis (Seoul)
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4499597
  • [Keywords] NOTNLM ; Fibromatosis, Aggressive / Multiple Pulmonary Nodules / Thorax
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60. Zeng WG, Zhou ZX, Liang JW, Hou HR, Wang Z, Zhou HT, Zhang XM, Hu JJ: Prognostic factors for desmoid tumor: a surgical series of 233 patients at a single institution. Tumour Biol; 2014 Aug;35(8):7513-21
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Prognostic factors for desmoid tumor: a surgical series of 233 patients at a single institution.
  • Desmoid tumors are rare soft tissue tumors with limited data on their management and prognosis.
  • We sought to determine the rates of recurrence after surgery for desmoid tumors and analyze factors predictive of recurrence-free survival (RFS).
  • From February 1976 to October 2011, 233 consecutive patients with desmoid tumors who underwent macroscopically complete resection were included in this study.
  • Patterns of presentation included primary (n = 156, 67.0 %) and locally recurrent (n = 77, 33.0 %) disease initially treated elsewhere.
  • Median follow-up was 54 months; recurrence disease was observed in 62 (26.6 %) patients.
  • Factors associated with worse RFS were tumor size larger than 5 cm (hazard ratio (HR) = 3.757; 95 % CI, 1.945-7.259; p < 0.001), extra-abdominal tumor location (abdominal wall referent; HR = 3.373; 95 % CI, 1.425-7.984; p = 0.006), and R1 resection status (HR = 1.901; 95 % CI, 1.140-3.171; p = 0.014).
  • Regardless of primary or recurrent disease, surgical resection remains central to the management of patients with desmoid tumors.
  • [MeSH-major] Fibromatosis, Aggressive / mortality

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  • (PMID = 24789435.001).
  • [ISSN] 1423-0380
  • [Journal-full-title] Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
  • [ISO-abbreviation] Tumour Biol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
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61. Kim SH, Kim DJ, Kim W: Long-Term Survival Following Port-Site Metastasectomy in a Patient with Laparoscopic Gastrectomy for Gastric Cancer: A Case Report. J Gastric Cancer; 2015 Sep;15(3):209-13
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  • During the six-month follow-up evaluation, a 2 cm enhancing mass confined to the muscle layer was found 12 mm from the right lower quadrant port site, suggesting a metastatic or desmoid tumor.
  • We confirmed that there was no intra-abdominal metastasis by diagnostic laparoscopy and then performed a wide resection of the recurrent mass.
  • There was no evidence of tumor recurrence during the 50-month follow-up period.

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  • (PMID = 26468419.001).
  • [ISSN] 2093-582X
  • [Journal-full-title] Journal of gastric cancer
  • [ISO-abbreviation] J Gastric Cancer
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Korea (South)
  • [Other-IDs] NLM/ PMC4604336
  • [Keywords] NOTNLM ; Laparoscopy / Metastasectomy / Recurrence
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62. Conroy EM, Frimer M, Karabakhtsian RG, Gorlick R, Goldberg GL: Vulvar fibromatosis: a clinical enigma. J Pediatr Hematol Oncol; 2015 Jan;37(1):63-7
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  • [Title] Vulvar fibromatosis: a clinical enigma.
  • OBJECTIVE: To present a case of recurrent vulvar fibromatosis in an adolescent, discuss the specific difficulties of treating adolescents, and review the literature on available treatment.
  • METHODS: We present a case of recurrent vulvar fibromatosis in a 14-year-old girl, requiring several treatment modalities, including multiple surgeries, radiation therapy, and multiagent chemotherapy.
  • We then discuss management strategies for these tumor types, and specifically examine how tumor location may impact their treatment.
  • CONCLUSIONS: Desmoid tumors are nonmalignant, locally aggressive neoplasms most common in the 15 to 60 years age group.
  • Most commonly, desmoid tumors present in the abdominal wall, shoulder, neck, and chest, but can occur anywhere in the body.
  • Given their rarity and lack of definitive therapy, vulvar desmoid tumors can be exceedingly difficult to treat, and are best managed with an interdisciplinary approach.

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  • (PMID = 25238226.001).
  • [ISSN] 1536-3678
  • [Journal-full-title] Journal of pediatric hematology/oncology
  • [ISO-abbreviation] J. Pediatr. Hematol. Oncol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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63. Hammer J, Léonard D, Chateau F, Abbes Orabi N, Ciccarelli O, Bachmann R, Remue C, Lengelé B, Kartheuser A: Reconstruction of an abdominal wall defect with biologic mesh after resection of a desmoid tumor in a patient with a Gardner's syndrome. Acta Chir Belg; 2017 Feb;117(1):55-60
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  • [Title] Reconstruction of an abdominal wall defect with biologic mesh after resection of a desmoid tumor in a patient with a Gardner's syndrome.
  • INTRODUCTION: Desmoid tumors are rare proliferative and invasive benign lesions.
  • They can be sporadic, but in most instances, desmoid tumors develop in the context of Gardner's syndrome with principal localization in the abdominal cavity and abdominal wall.
  • CASE-REPORT: We report the case of a 24-year-old female presenting Gardner's syndrome with a symptomatic abdominal wall desmoid tumor.
  • DISCUSSION: Conventional treatment of abdominal wall desmoid tumors consists in a wide and radical resection.
  • However, complete resection is not always feasible because of difficulty to differentiate the desmoid tumor from adjacent tissues.
  • CONCLUSION: We have encountered a case of a symptomatic growing desmoid tumor of the abdominal wall in a young patient with Gardner's syndrome, successfully treated by complete resection and reconstruction with a biologic mesh to correct the parietal defect.
  • [MeSH-major] Abdominal Wall / surgery. Fibromatosis, Abdominal / surgery. Gardner Syndrome / complications. Surgical Mesh

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  • (PMID = 27538186.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Abdominal wall reconstruction (major topic) / Gardner’s syndrome (major topic) / biologic mesh (major topic) / desmoid tumor (major topic) / familial adenomatous polyposis (major topic)
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64. Alanis L, Roth R, Lerman N, Barroeta JE, Germaine P: Radiologic images of an aggressive implant-associated fibromatosis of the breast and chest wall: case report and review of the literature. Radiol Case Rep; 2017 Sep;12(3):431-438
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  • [Title] Radiologic images of an aggressive implant-associated fibromatosis of the breast and chest wall: case report and review of the literature.
  • Fibromatosis of the breast is a rare benign disease compromising <0.2% of all primary breast tumors.
  • Although the chest wall is a common location, occurrences of implant-associated fibromatosis of the breast are extremely rare; only 33 cases have been reported.
  • We present a case of a 42-year-old female who underwent breast augmentation with silicone breast implants, and 2 years later developed an aggressive implant-associated fibromatosis of the breast and chest wall.
  • On imaging studies, the tumor mimicked breast carcinoma, and despite chemotherapy, the fibromatosis rapidly enlarged and was locally invasive requiring wide surgical excision.
  • We provide a review of the literature and discuss the imaging features of implant-associated fibromatosis of the breast.

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  • (PMID = 28828097.001).
  • [ISSN] 1930-0433
  • [Journal-full-title] Radiology case reports
  • [ISO-abbreviation] Radiol Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Netherlands
  • [Keywords] NOTNLM ; Breast cancer / Breast fibromatosis / Breast implants / Chest wall / Desmoid tumor / Extra-abdominal tumor / Magnetic resonance imaging / Mammography / Pathology / Ultrasonography
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65. Wang YC, Wong JU: Complete remission of pancreatic head desmoid tumor treated by COX-2 inhibitor-a case report. World J Surg Oncol; 2016 Jul 22;14(1):190
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  • [Title] Complete remission of pancreatic head desmoid tumor treated by COX-2 inhibitor-a case report.
  • BACKGROUND: Desmoid tumors (DTs) are non-metastatic, locally aggressive neoplasms with high postoperative recurrence rates.
  • Cyclooxygenase-2 (COX-2) has been demonstrated to play a role in the growth of DTs, and the pharmacologic blockade of COX resulted in decreased cell proliferation in desmoid cell cultures in vitro.
  • An abdominal computed tomography scan showed an approximately 10-cm mass over the pancreatic head region and dilatation of the pancreatic duct.
  • Tumor biopsy and bypass surgery were performed.
  • [MeSH-major] Abdominal Pain / drug therapy. Cyclooxygenase 2 Inhibitors / therapeutic use. Fibromatosis, Aggressive / drug therapy. Pancreatic Neoplasms / drug therapy

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  • (PMID = 27450394.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Cyclooxygenase 2 Inhibitors
  • [Other-IDs] NLM/ PMC4957301
  • [Keywords] NOTNLM ; Aggressive fibromatosis (major topic) / Cyclooxygenase-2 inhibitor (major topic) / Desmoid tumor (major topic) / Non-steroidal anti-inflammatory drugs (major topic) / Pancreatic head (major topic)
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66. d'Alena FC, Di Marco C, Loponte M, Pirozzi C, Savino G: Sporadic aggressive fibromatosis of the colon and abdominal wall in an emergency setting. Ann Ital Chir; 2015 Dec 28;86(ePub):S2239253X15024731
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  • [Title] Sporadic aggressive fibromatosis of the colon and abdominal wall in an emergency setting.
  • AIM: Our aim is to present an utterly unique case of sporadic aggressive fibromatosis (AF), infiltrating both the abdominal wall and the colon; and especially, to discuss the usefulness of porcine dermal meshes for the reconstruction of a large parietal gap in contaminated surgery and in an emergency setting.
  • CASE EXPERIENCE: We report the case of a 40 years old woman affected by sporadic AF, involving both the anterior abdominal wall and the colon, with an effective intestinal stricture.
  • The surgery consisted in removing "en bloc" the portions of the colon and abdominal wall affected by fibromatosis, with no residual tumor (R0), that left an important parietal gap.
  • A biological prosthesis of cross-linked acellular porcine dermal collagen (APDC) has been used for the contextual reconstruction of the abdominal wall, sutured inlay by a double line of non absorbable stitches.
  • After one year follow up, there is no tumour recurrence and the abdominal wall has fully consolidated.
  • DISCUSSION: The peculiar problems arising about differential diagnosis, therapeutic indications and reconstructive surgical procedures are discussed, especially with regard to prosthetic implants in contaminated surgery and to cross-linked APDC prosthesis.
  • According to our experience, cross-linked APDC is effective for the prosthetic reconstruction of abdominal wall in contaminated surgery and in an emergency setting.
  • KEY WORDS: Abdominal wall, Aggressive fibromatosis, Desmoid tumor, Prosthetic devices, Reconstructive surgical procedures, desmoid tumor.
  • [MeSH-major] Abdominal Neoplasms / surgery. Abdominal Wall / surgery. Colonic Neoplasms / surgery. Emergency Service, Hospital. Fibromatosis, Aggressive / surgery. Surgical Mesh


67. Khanna M, Ramanathan S, Kambal AS, Al-Berawi M, Yadav S, Kumar D, Schieda N: Multi-parametric (mp) MRI for the diagnosis of abdominal wall desmoid tumors. Eur J Radiol; 2017 Jul;92:103-110
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  • [Title] Multi-parametric (mp) MRI for the diagnosis of abdominal wall desmoid tumors.
  • INTRODUCTION: Desmoid tumors are benign myofibroblastic neoplasms, originating from the muscle aponeurosis and classified as deep fibromatoses.
  • The aim of this study was to evaluate the utility of multi-parametric (mp)-MRI for the diagnosis of abdominal wall desmoid tumor (awdt).
  • MATERIAL AND METHODS: This Institutional review board approved retrospective study compared 10 patients (mean age±SD; 38.2±13years; 9 females and 1 male) with awdt to 14 subjects (mean age±SD; 45.6±14.7years; 9 females and 5 males) with non-desmoid abdominal wall tumors (ndawt).

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  • [Copyright] Copyright © 2017 Elsevier B.V. All rights reserved.
  • (PMID = 28624006.001).
  • [ISSN] 1872-7727
  • [Journal-full-title] European journal of radiology
  • [ISO-abbreviation] Eur J Radiol
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Ireland
  • [Keywords] NOTNLM ; Abdominal wall desmoid tumor / Diffusion weighted imaging / Dynamic contrast enhancement / MRI
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68. Ghanouni P, Dobrotwir A, Bitton R, Rosenberg J, Telischak K, Busacca M, Ferrari S, Albisinni U, Walters S, Gold G, Ganjoo K, Napoli A, Pauly KB, Avedian R: Magnetic resonance-guided focused ultrasound treatment of extra-abdominal desmoid tumors: a retrospective multicenter study. Eur Radiol; 2017 Feb;27(2):732-740
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  • [Title] Magnetic resonance-guided focused ultrasound treatment of extra-abdominal desmoid tumors: a retrospective multicenter study.
  • OBJECTIVES: To assess the feasibility, safety and preliminary efficacy of magnetic resonance-guided focused ultrasound (MRgFUS) for the treatment of extra-abdominal desmoid tumours.
  • METHODS: Fifteen patients with desmoid fibromatosis (six males, nine females; age range, 7-66 years) were treated with MRgFUS, with seven patients requiring multiple treatments (25 total treatments).
  • Changes in viable and total tumour volumes were measured after treatment.
  • Efficacy was evaluated using an exact one-sided Wilcoxon test to determine if the median reduction in viable tumour measured immediately after initial treatment exceeded a threshold of 50 % of the targeted volume.
  • RESULTS: After initial MRgFUS treatment, median viable targeted tumour volume decreased 63 %, significantly beyond our efficacy threshold (P = 0.0013).
  • Median viable total tumour volume decreased (105 mL [interquartile range {IQR}, 217 mL] to 54 mL [IQR, 92 mL]) and pain improved (worst scores, 7.5 ± 1.9 vs 2.7 ± 2.6, P = 0.027; average scores, 6 ± 2.3 vs 1.3 ± 2, P = 0.021).
  • CONCLUSIONS: MRgFUS significantly and durably reduced viable tumour volume and pain in this series of 15 patients with extra-abdominal desmoid fibromatosis.
  • KEY POINTS: • Retrospective four-centre study shows MRgFUS safely and effectively treats extra-abdominal desmoid tumours • This non-invasive procedure can eradicate viable tumour in some cases • Alternatively, MRgFUS can provide durable control of tumour growth through repeated treatments • Compared to surgery or radiation, MRgFUS has relatively mild side effects.
  • [MeSH-major] Fibromatosis, Aggressive / surgery. High-Intensity Focused Ultrasound Ablation / methods. Magnetic Resonance Imaging, Interventional / methods. Soft Tissue Neoplasms / surgery
  • [MeSH-minor] Adolescent. Adult. Aged. Child. Female. Humans. Magnetic Resonance Imaging. Male. Middle Aged. Retrospective Studies. Surgery, Computer-Assisted. Treatment Outcome. Tumor Burden. Young Adult

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  • (PMID = 27147222.001).
  • [ISSN] 1432-1084
  • [Journal-full-title] European radiology
  • [ISO-abbreviation] Eur Radiol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P01 CA159992
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Desmoid fibromatosis / High-intensity focused ultrasound (HIFU) / MR-guided focused ultrasound / MRgFUS / Thermal ablation
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69. Jenayah AA, Bettaieb H, Saoudi S, Gharsa A, Sfar E, Boudaya F, Chelli D: Desmoid tumors: clinical features and treatment options: a case report and a review of literature. Pan Afr Med J; 2015;21:93
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  • [Title] Desmoid tumors: clinical features and treatment options: a case report and a review of literature.
  • Desmoid tumors are a rare group of locally aggressive, non malignant tumors of fibroblastic origin that can lead to significant morbidity due to local invasion and may even result in a fatal outcome when located around vital organs.
  • [MeSH-major] Abdominal Pain / etiology. Fibromatosis, Aggressive / diagnosis

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  • (PMID = 26516394.001).
  • [ISSN] 1937-8688
  • [Journal-full-title] The Pan African medical journal
  • [ISO-abbreviation] Pan Afr Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Uganda
  • [Other-IDs] NLM/ PMC4606030
  • [Keywords] NOTNLM ; Desmoïd tumor / radiotherapy / recurrence / surgery
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70. Cromme F, Brüner S, Wittig KS, Grzybowski S: [Desmoid tumour around the DIEP anastomosis - a rare complication after breast reconstruction]. Handchir Mikrochir Plast Chir; 2014 Apr;46(2):116-20
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  • [Title] [Desmoid tumour around the DIEP anastomosis - a rare complication after breast reconstruction].
  • Abdominal desmoid tumors are so called non-metastatic tumors.
  • After breast reconstruction with a DIEP flap (Deep Inferior epigastric Artery Perforator Flap), a progressive growth of a desmoid tumor was seen around the DIEP-anastomosis.
  • [MeSH-major] Anastomosis, Surgical. Breast Neoplasms / diagnosis. Breast Neoplasms / surgery. Epigastric Arteries / surgery. Fibroma / diagnosis. Mammaplasty. Perforator Flap / surgery. Postoperative Complications / diagnosis

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  • [Copyright] © Georg Thieme Verlag KG Stuttgart · New York.
  • (PMID = 24777462.001).
  • [ISSN] 1439-3980
  • [Journal-full-title] Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft für Mikrochirurgie der Peripheren Nerven und Gefässe : Organ der Vereinigung der Deutschen Plastischen Chirurgen
  • [ISO-abbreviation] Handchir Mikrochir Plast Chir
  • [Language] ger
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Germany
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71. Shin R, Cho HS, Kim DW, Ahn SY, Ihn MH, Park HJ, Oh HK, Kang SB: Does routine colonoscopy help diagnose familial adenomatous polyposis in patients presenting with desmoid tumors but no gastrointestinal symptoms? Int J Colorectal Dis; 2017 Jan;32(1):151-154
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  • [Title] Does routine colonoscopy help diagnose familial adenomatous polyposis in patients presenting with desmoid tumors but no gastrointestinal symptoms?
  • PURPOSE: Desmoid tumor (DT) is a rare myofibroblastic proliferative neoplasm, but can occur in up to 26% of patients with familial adenomatous polyposis (FAP).
  • The aim of this study was to identify the incidence of polyps in DT patients and investigate value of colonoscopy for diagnosis of FAP in DT patients without gastrointestinal symptoms.
  • Clinical data, including location of tumor, type(s) of treatment, and colonoscopic findings, were collected.
  • RESULTS: Sixty-five patients were diagnosed with DT during the study period; 10 patients received colonoscopies before diagnosis of DT, and 20 patients received colonoscopies after diagnosis of DT.
  • The mean age at diagnosis of DT was 41.9 ± 16.7 years old (range 17-74).
  • Most tumors were extra-abdominal (n = 24, 80.0%), and fewer were intra-abdominal (n = 4, 13.3%) or in an abdominal wall (n = 2, 6.7%).
  • [MeSH-major] Adenomatous Polyposis Coli / complications. Adenomatous Polyposis Coli / diagnosis. Colonoscopy. Fibromatosis, Aggressive / complications. Fibromatosis, Aggressive / diagnosis

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  • (PMID = 27844202.001).
  • [ISSN] 1432-1262
  • [Journal-full-title] International journal of colorectal disease
  • [ISO-abbreviation] Int J Colorectal Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Adenomatous polyposis coli (major topic) / Colonoscopy (major topic) / Desmoid disease (major topic)
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72. Abbonante F, Ribuffo D, Vitagliano T, Fiorillo MA, Ciriaco AG, Conversi A, Greco M: Abdominal desmoid tumors. A new reconstructive approach. Ann Ital Chir; 2015 Jan-Feb;86(1):78-84
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  • [Title] Abdominal desmoid tumors. A new reconstructive approach.
  • INTRODUCTION: Desmoid tumors are rare soft tissue tumors derived from musculoaponeurotic structures of the abdominal wall musculature.
  • METHODS: Nine female patients with abdominal desmoid tumors underwent the removal of a mass of tissue running from the skin to peritoneum near the tumor with a safety margin in macroscopically normal tissue at least of 5 centimeters from the edge of the tumor.
  • After wide excision, a polypropylene mesh was placed in the rear muscular pocket without anchoring suture (sliding mesh sutureless hernioplasty) RESULTS: No patients had perioperative complications or abdominal wall weakness or an incisional hernia in the following 5 years.
  • CONCLUSIONS: We consider this technique of abdominal wall reconstruction after desmoid tumor removal a simple procedure that reduces relapsing events and recurrences of abdominal hernia, reducing tension and pain caused by the traditional suture repair technique.
  • [MeSH-major] Abdominal Neoplasms / surgery. Abdominal Wall / surgery. Fibromatosis, Aggressive / surgery. Reconstructive Surgical Procedures / methods

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  • (PMID = 25817632.001).
  • [ISSN] 2239-253X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Italy
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73. Teixeira LE, Arantes EC, Villela RF, Soares CB, Costa RB, Andrade MA: EXTRA-ABDOMINAL DESMOID TUMOR: LOCAL RECURRENCE AND TREATMENT OPTIONS. Acta Ortop Bras; 2016 May-Jun;24(3):147-50
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  • [Title] EXTRA-ABDOMINAL DESMOID TUMOR: LOCAL RECURRENCE AND TREATMENT OPTIONS.
  • OBJECTIVE: To evaluate the rate of local recurrence of extra-abdominal desmoid tumor and compare the outcomes of surgical treatment and conservative treatment.
  • METHODS: Twenty one patients (14 women and seven men), mean age 33.0±8.7 years old, with a diagnosis of desmoid tumor were evaluated.
  • The average tumor size was 12.7±7.5 cm.
  • CONCLUSION: The recurrence rate of desmoid tumor was 33.3%.

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  • (PMID = 27217816.001).
  • [ISSN] 1413-7852
  • [Journal-full-title] Acta ortopedica brasileira
  • [ISO-abbreviation] Acta Ortop Bras
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
  • [Other-IDs] NLM/ PMC4863863
  • [Keywords] NOTNLM ; Fibromatosis, aggressive / Medical oncology / Recurrence
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74. Gurluler E, Gures N, Citil I, Kemik O, Berber I, Sumer A, Gurkan A: Desmoid tumor in puerperium period: a case report. Clin Med Insights Case Rep; 2014;7:29-32
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  • [Title] Desmoid tumor in puerperium period: a case report.
  • Desmoid tumors (DTs) are rare tumors classified as deep fibromatoses taking origin from fascial or musculoaponeurotic structures.
  • With pregnancy and surgical scars considered in the etiology, most anterior abdominal wall DTs occur in women in their reproductive years, especially during a pregnancy or post-partum.
  • Herein, we present development of DT in a female patient in the post-partum period following cesarean delivery, which manifested itself with a growing mass in anterior abdominal wall.
  • In our case, possibility of hematoma most probably located beneath the fascia was considered initially as a complication of cesarean section based on ultrasonographic examination and location of the lesion, while upon lack of either spontaneous regression with eventual diminish in size or resolve of symptoms within six weeks, further investigation via MRI and tru-cut biopsy revealed the diagnosis of abdominal DT.
  • Radical tumor extirpation with resection of an adequate margin of surrounding normal tissue was applied, and the post-operative period was uneventful.

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  • (PMID = 24678243.001).
  • [Journal-full-title] Clinical medicine insights. Case reports
  • [ISO-abbreviation] Clin Med Insights Case Rep
  • [Language] ENG
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Other-IDs] NLM/ PMC3964204
  • [Keywords] NOTNLM ; desmoid tumor / puerperium
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75. Ooi S, Ngo H: Cesarean section after abdominal mesh repair for pregnancy-related desmoid tumor: a case report. Int J Womens Health; 2017;9:497-499
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  • [Title] Cesarean section after abdominal mesh repair for pregnancy-related desmoid tumor: a case report.
  • We report the case of a 32-year-old gravida 2 para 1 woman with a background of partially resected desmoid tumor (DT) arising from the previous cesarean section (CS) scar.
  • To our knowledge, this is the only report to illustrate that subsequent CS is possible after desmoid resection and abdominal mesh repair.
  • It provides evidence that CS can be safely accomplished following abdominal wall reconstructions and further arguments against elective lower segment CS.

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  • [ISSN] 1179-1411
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  • [ISO-abbreviation] Int J Womens Health
  • [Language] eng
  • [Publication-type] Journal Article
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  • [Keywords] NOTNLM ; abdominal wall / cesarean section / complications / desmoid tumor / surgical mesh
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76. Walter T, Zhenzhen Wang C, Guillaud O, Cotte E, Pasquer A, Vinet O, Poncet G, Ponchon T, Saurin JC: Management of desmoid tumours: A large national database of familial adenomatous patients shows a link to colectomy modalities and low efficacy of medical treatments. United European Gastroenterol J; 2017 Aug;5(5):735-741
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  • [Title] Management of desmoid tumours: A large national database of familial adenomatous patients shows a link to colectomy modalities and low efficacy of medical treatments.
  • BACKGROUND: Desmoid tumours represent a major complication of familial adenomatous polyposis.
  • Our aims were to study the factors associated with the development of desmoid tumours in familial adenomatous polyposis patients, and to describe presentation and management of desmoid tumours.
  • Response to treatment of desmoid tumours was assessed by Response Evaluation Criteria In Solid Tumor (RECIST) criteria.
  • RESULTS: A total of 180 patients with familial adenomatous polyposis were included with a median follow-up of 19 years since diagnosis.
  • Thirty-one (17%) patients developed 58 desmoid tumours, a median (range) 4.7 (0.8-41.6) years after their diagnosis of familial adenomatous polyposis.
  • The only factor significantly associated with occurrence of desmoid tumours was the type of surgery: 12 (12%) desmoid tumours in 104 patients treated by colectomy, versus 19 (25%) desmoid tumours in 76 patients treated by proctocolectomy, <i>p</i> = 0.027.
  • The localisation of desmoid tumours was: mesenteric (<i>n</i> = 25), abdominal wall (<i>n</i> = 30) or extra-abdominal (<i>n</i> = 3).
  • Nineteen patients underwent 36 surgical procedures for desmoid tumours.
  • CONCLUSION: If confirmed, colectomy (versus proctocolectomy) should be performed in adenomatous polyposis coli-related familial adenomatous polyposis patients to avoid desmoid tumours.
  • We show that there is a high prevalence of post-surgical recurrence and the low efficacy of available medical treatments for desmoid tumours.

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  • (PMID = 28815038.001).
  • [ISSN] 2050-6406
  • [Journal-full-title] United European gastroenterology journal
  • [ISO-abbreviation] United European Gastroenterol J
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Desmoid tumour / familial adenomatous polyposis / risk factor / surgery / treatment
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77. Diebels I, Blockhuys M, Willemsen P, Pirenne Y: Embolization of a large progressive symptomatic desmoid tumor in the rectus muscle of a female patient with multiple sclerosis: a case report. Acta Chir Belg; 2017 Jun 22;:1-4
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  • [Title] Embolization of a large progressive symptomatic desmoid tumor in the rectus muscle of a female patient with multiple sclerosis: a case report.
  • INTRODUCTION: Desmoid tumors are benign tumors, yet can lead to significant morbidity due to aggressive local expansions.
  • Treatment starts with a wait-and-see policy, however, more aggressive treatments like broad margin resection surgery might be necessary in case of tumor progression.
  • PATIENTS AND METHODS: We report the case of a 26-year-old female with a symptomatic desmoid tumor in the left rectus muscle.
  • The initial wait-and-see policy led to an increase in tumor size and progression of symptoms.
  • RESULTS: At three months follow-up, the patient was asymptomatic and magnetic resonance imaging (MRI) showed no residual tumor.
  • CONCLUSIONS: Embolization of a primary supplying vessel of a desmoid tumor is a viable treatment option.

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  • (PMID = 28641503.001).
  • [ISSN] 0001-5458
  • [Journal-full-title] Acta chirurgica Belgica
  • [ISO-abbreviation] Acta Chir. Belg.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Desmoid / abdominal wall surgery / aggressive fibromatosis / embolization / multiple sclerosis
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78. Ohtake S, Namura K, Fujikawa A, Sawada T, Ohta J, Moriyama M, Hayashi H: [A Case of Abdominal Wall Desmoid Tumor after Radical Nephrectomy for Renal Cancer]. Hinyokika Kiyo; 2015 Sep;61(9):353-7
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  • [Title] [A Case of Abdominal Wall Desmoid Tumor after Radical Nephrectomy for Renal Cancer].
  • A 71-year-old man with a right renal tumor underwent nephrectomy.
  • Pathological diagnosis was clear cell carcinoma G2pT3b v1 ly1 INFα.
  • Three years after surgery, a 5 cm tumor in the abdominal wall was found on computed tomography (CT).
  • A mild uptake was shown on positron emission tomography/CT and as the tumor was located near the surgical wound, recurrence of the renal cell carcinoma was suspected.
  • However, desmoid tumor was suggested by the pathological examination of the tumor biopsy.
  • En-bloc resection of the mass was carried out and the pathological examination showed an array of proliferating and tangling atypical spindle-shaped tumor cells.
  • Immunohistochemical staining of the tumor cells was positive for vimentin, but negative for CD34, c-kit, and s100.
  • Pathological diagnosis was desmoid tumor.
  • Desmoid tumor, despite its extremely low incidence, should be considered in a postoperative neoplasm.
  • [MeSH-major] Abdominal Neoplasms / etiology. Abdominal Wall. Fibromatosis, Aggressive / etiology. Kidney Neoplasms / surgery. Nephrectomy
  • [MeSH-minor] Aged. Diagnosis, Differential. Humans. Male. Neoplasm Recurrence, Local / diagnosis. Postoperative Complications

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  • (PMID = 26497861.001).
  • [ISSN] 0018-1994
  • [Journal-full-title] Hinyokika kiyo. Acta urologica Japonica
  • [ISO-abbreviation] Hinyokika Kiyo
  • [Language] jpn
  • [Publication-type] Case Reports; English Abstract; Journal Article
  • [Publication-country] Japan
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79. van Broekhoven DL, Grunhagen DJ, Verhoef C: Abdominal Desmoid Tumors: Hands Off? Ann Surg Oncol; 2016 Jul;23(7):2128-30
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  • [Title] Abdominal Desmoid Tumors: Hands Off?

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  • (PMID = 26957505.001).
  • [ISSN] 1534-4681
  • [Journal-full-title] Annals of surgical oncology
  • [ISO-abbreviation] Ann. Surg. Oncol.
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] United States
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80. Villalón-López JS, Souto-del Bosque R, Méndez-Sashida PG: [Proctocolectomy with ileoanal anastomoses and desmoid tumor treated with resection. One case of familial adenomatous polyposis]. Rev Med Inst Mex Seguro Soc; 2014 Sep-Oct;52(5):594-7
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  • [Title] [Proctocolectomy with ileoanal anastomoses and desmoid tumor treated with resection. One case of familial adenomatous polyposis].
  • [Transliterated title] Proctocolectomía con anastomosis íleo-anal y resección de tumor desmoide. Un caso de poliposis adenomatosa familiar.
  • BACKGROUND: Familial adenomatous polyposis (FAP) is a rare disease caused by a mutation in the adenomatous polyposis coli gene (APC).
  • CASE REPORT: We report the case of a 32-year-old woman, with abdominal pain and increased abdominal perimeter, as well as melena and weight loss.
  • She had a tumor of 12 cm in diameter in the right iliac fossa.
  • After the administration of contrast media we found the abdominal tumor compatible with sarcoma versus desmoid tumor.
  • Tumor resection was performed with abdominal wall reconstruction with mesh and restorative proctocolectomy with ileoanal reservoir and a temporary ileostomy.
  • The histopathology report demonstrated an abdominal wall desmoid tumor and identified 152 tubulovillous polyps which affected all the portions of colon and rectum.
  • CONCLUSIONS: FAP is an autosomal dominant disease caused by a mutation in the APC gene which results in the development of multiple colorectal polyps.
  • Desmoid tumors and duodenal polyps are now the leading cause of death in patients with FAP.
  • Introducción: la poliposis adenomatosa familiar (PAF) es una rara enfermedad causada por una mutación en el gen de la poliposis adenomatosa coli (APC).
  • Caso clínico: mujer de 32 años, con dolor y aumento del perímetro abdominal además de evacuaciones melénicas y pérdida de peso.
  • La paciente presentó un tumor de 12 cm de diámetro en la fosa iliaca derecha.
  • Tras la administración de medio de contraste, en una tomografía se apreció el tumor abdominal con reforzamiento compatible con sarcoma frente a tumor desmoide.
  • Se realizó colonoscopia, por medio de la que se encontraron pólipos en el recto y el colon.
  • Se realizó resección del tumor en pared abdominal y reconstrucción con malla además de proctocolectomía restaurativa con un reservorio íleo-anal con una ileostomía temporal.
  • Se reportó tumor desmoide en la pared abdominal y se identificaron 152 pólipos túbulo-vellosos que afectaban todas las porciones del colon y el recto.
  • Conclusiones: la PAF es una enfermedad autosómica dominante causada por una mutación en el gen APC que da como resultado el desarrollo de múltiples pólipos tanto en el colon como en el recto.
  • Sin cirugía profiláctica, todos los pacientes desarrollarán cáncer colorrectal en la tercera década de la vida.
  • Los tumores desmoides y los pólipos duodenales son ahora la causa de muerte en los pacientes con PAF.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Anal Canal / surgery. Fibromatosis, Aggressive / surgery. Ileum / surgery

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  • (PMID = 25301135.001).
  • [ISSN] 0443-5117
  • [Journal-full-title] Revista medica del Instituto Mexicano del Seguro Social
  • [ISO-abbreviation] Rev Med Inst Mex Seguro Soc
  • [Language] spa
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Mexico
  • [Keywords] NOTNLM ; Adenomatous polyposis coli / Colonic pouches / Fibromatosis, abdominal / Proctocolectomy, restorative
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81. Nair KK, Chaudhuri K, Lingappa A, Shetty R, Vittobarao PG: Aggressive fibromatosis of the oral cavity in a 5 year old boy: a rare case report. Pan Afr Med J; 2017;27:47
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  • [Title] Aggressive fibromatosis of the oral cavity in a 5 year old boy: a rare case report.
  • Fibrous tissue proliferations express a wide spectrum of histologic and morphologic variation in both infants and adults.
  • Aggressive fibromatosis is an intermediate tumor which is in proximity to fibrosarcomas.
  • Aggressive fibromatosis in the head and neck region is not common, and very sporadically occurs in the oral cavity or jaw bones.
  • Here we report a rare case of aggressive fibromatosis occurring in a 5 year old boy.
  • [MeSH-major] Fibromatosis, Aggressive / diagnosis. Mouth Neoplasms / diagnosis

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  • (PMID = 28819469.001).
  • [ISSN] 1937-8688
  • [Journal-full-title] The Pan African medical journal
  • [ISO-abbreviation] Pan Afr Med J
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Uganda
  • [Keywords] NOTNLM ; Aggressive fibromatosis / desmoid tumor / extra-abdominal fibromatosis / infantile fibromatosis / soft tissue tumor
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82. Thway K, Abou Sherif S, Riddell AM, Mudan S: Fibromatosis of the Sigmoid Colon With CTNNB1 (β-Catenin) Gene Mutation, Arising at the Site of Ileocolic Anastomosis for Resection of Gastrointestinal Stromal Tumor. Int J Surg Pathol; 2016 May;24(3):264-8
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  • [Title] Fibromatosis of the Sigmoid Colon With CTNNB1 (β-Catenin) Gene Mutation, Arising at the Site of Ileocolic Anastomosis for Resection of Gastrointestinal Stromal Tumor.
  • We describe a case of intra-abdominal fibromatosis, which occurred in a 44-year-old woman who had a previous history of gastrointestinal stromal tumor (GIST) of the sigmoid mesocolon, which was treated with imatinib and resection.
  • Clinically, this was suspected to represent recurrent GIST and was excised, but histology and mutational analysis showed desmoid-type fibromatosis with a mutation in codon 41 of exon 3 of the CTNNB1 (β-catenin) gene.
  • The occurrence of fibromatosis at the site of excision of GIST is very rare, but its recognition is important as the treatment of the two neoplasms differs significantly.
  • As imaging cannot reliably distinguish between these 2 entities, histological diagnosis is crucial for correct clinical management.

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  • [Copyright] © The Author(s) 2015.
  • (PMID = 26721303.001).
  • [ISSN] 1940-2465
  • [Journal-full-title] International journal of surgical pathology
  • [ISO-abbreviation] Int. J. Surg. Pathol.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / CTNNB1 protein, human; 0 / beta Catenin
  • [Keywords] NOTNLM ; CTNNB1 (β-catenin) gene (major topic) / anastomosis (major topic) / fibromatosis (major topic) / gastrointestinal stromal tumor (major topic) / large bowel (major topic) / molecular (major topic) / mutational analysis (major topic) / post surgery (major topic) / sarcoma (major topic) / sigmoid colon (major topic) / small bowel (major topic) / soft tissue (major topic)
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83. Tzur R, Silberstein E, Krieger Y, Shoham Y, Rafaeli Y, Bogdanov-Berezovsky A: Desmoid Tumor and Silicone Breast Implant Surgery: Is There Really a Connection? A Literature Review. Aesthetic Plast Surg; 2017 Aug 25;
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  • [Title] Desmoid Tumor and Silicone Breast Implant Surgery: Is There Really a Connection? A Literature Review.
  • BACKGROUND: Desmoid tumors are borderline tumors of the connective tissue, arising in the musculo-aponeurotic stromal elements.
  • A desmoid tumor (DT) has an infiltrative and locally aggressive growth pattern and usually does not metastasize; however, it has a high recurrence and complication rate.
  • DT located in the breast (BDT) represents a rare extra-abdominal form.
  • At the moment, a possible association between breast implants and the development of breast desmoid tumors cannot be unequivocally confirmed.

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  • (PMID = 28842766.001).
  • [ISSN] 1432-5241
  • [Journal-full-title] Aesthetic plastic surgery
  • [ISO-abbreviation] Aesthetic Plast Surg
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Aggressive fibromatosis / Augmentation mammaplasty / Breast augmentation / Breast desmoid / Desmoid tumor / Silicone implant
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84. Levy AD, Manning MA, Miettinen MM: Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 2-Uncommon Sarcomas. Radiographics; 2017 May-Jun;37(3):797-812
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  • [Title] Soft-Tissue Sarcomas of the Abdomen and Pelvis: Radiologic-Pathologic Features, Part 2-Uncommon Sarcomas.
  • Soft-tissue sarcomas occurring in the abdomen and pelvis are an uncommon but important group of malignancies.
  • Recent changes to the World Health Organization classification of soft-tissue tumors include the movement of gastrointestinal stromal tumors (GISTs) into the soft-tissue tumor classification.
  • Liposarcoma is the most common retroperitoneal sarcoma, and leiomyosarcoma is the second most common.
  • GIST, liposarcoma, and leiomyosarcoma account for the majority of sarcomas encountered in the abdomen and pelvis and are discussed in part 1 of this article.
  • Undifferentiated pleomorphic sarcoma (previously called malignant fibrous histiocytoma), dermatofibrosarcoma protuberans, solitary fibrous tumor, malignant peripheral nerve sheath tumor, rhabdomyosarcoma, extraskeletal chondro-osseous sarcomas, vascular sarcomas, and sarcomas of uncertain differentiation uncommonly arise in the abdomen and pelvis and the abdominal wall.
  • The anatomic location and clinical history are important factors in the differential diagnosis of these lesions because metastasis, more-common sarcomas, borderline fibroblastic proliferations (such as desmoid tumors), and endometriosis have imaging findings that overlap with those of these uncommon sarcomas.
  • In this article, the clinical, pathologic, and imaging findings of uncommon soft-tissue sarcomas of the abdomen and pelvis and the abdominal wall are reviewed, with an emphasis on their differential diagnosis.
  • [MeSH-major] Abdomen / diagnostic imaging. Abdomen / pathology. Pelvis / diagnostic imaging. Pelvis / pathology. Sarcoma / diagnostic imaging. Sarcoma / pathology
  • [MeSH-minor] Diagnosis, Differential. Humans

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  • (PMID = 28493803.001).
  • [ISSN] 1527-1323
  • [Journal-full-title] Radiographics : a review publication of the Radiological Society of North America, Inc
  • [ISO-abbreviation] Radiographics
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] United States
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85. Wilder F, D'Angelo S, Crago AM: Soft tissue tumors of the trunk: management of local disease in the breast and chest and abdominal walls. J Surg Oncol; 2015 Apr;111(5):546-52
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  • [Title] Soft tissue tumors of the trunk: management of local disease in the breast and chest and abdominal walls.
  • This review summarizes the standard treatment of truncal sarcomas and considers how these recommendations differ for each of the various common histologic subtypes observed on the trunk: desmoid, dermatofibrosarcoma protuberans (DFSP), and angiosarcoma.
  • [MeSH-major] Abdominal Neoplasms / therapy. Breast Neoplasms / therapy. Sarcoma / therapy. Thoracic Neoplasms / therapy
  • [MeSH-minor] Abdominal Wall / pathology. Female. Humans. Torso / pathology

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  • [Copyright] © 2014 Wiley Periodicals, Inc.
  • (PMID = 25418423.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Grant] United States / NCI NIH HHS / CA / P30 CA008748
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't; Review
  • [Publication-country] United States
  • [Keywords] NOTNLM ; aggressive fibromatosis / angiosarcoma / dermatofibrosarcoma protuberans / desmoid / truncal sarcoma
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86. Kim YW, Choi SJ, Jeon UB, Choo KS: Retroperitoneal fibromatosis presenting as a presacral mass. Acta Radiol Short Rep; 2014 Feb;3(2):2047981614523760
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  • [Title] Retroperitoneal fibromatosis presenting as a presacral mass.
  • Aggressive fibromatosis arising from the retroperitoneum is extremely rare.
  • It may occur in association with previous trauma, abdominal surgery, drugs, Gardner's syndrome, or familial adenomatous polyposis.
  • We report a case of retroperitoneal fibromatosis presenting as a presacral mass with an infiltrating nature, relatively intense enhancement on enhanced computed tomography scanning, and low-signal intensity on T2-weighted magnetic resonance imaging in a patient with no significant medical or surgical history.

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  • (PMID = 24778806.001).
  • [ISSN] 2047-9816
  • [Journal-full-title] Acta radiologica short reports
  • [ISO-abbreviation] Acta Radiol Short Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Other-IDs] NLM/ PMC4001437
  • [Keywords] NOTNLM ; Fibromatosis / magnetic resonance imaging (MRI) / presacral mass / retroperitoneum
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87. Koskenvuo L, Peltomäki P, Renkonen-Sinisalo L, Gylling A, Nieminen TT, Ristimäki A, Lepistö A: Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis. J Surg Oncol; 2016 Feb;113(2):209-12
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  • [Title] Desmoid tumor patients carry an elevated risk of familial adenomatous polyposis.
  • BACKGROUND: The prevalence of desmoid tumors among patients with familial adenomatous polyposis (FAP) is at least 10%, and the prevalence of FAP among desmoid patients varies between 7.5-16%.
  • METHODS: Data included 106 desmoid patients identified from the database of the Department of Pathology, Helsinki University Hospital, years 2000-2012.
  • We compared sporadic desmoid patients' and FAP patients' clinical characteristics.
  • RESULTS: Ten of 106 patients already had FAP diagnosis before the desmoid.
  • Eleven patients had had FAP screening already earlier due to desmoid and three of them were found to have FAP.
  • The risk of FAP among desmoid tumor patients was 4.8%.
  • In the FAP desmoid group, there were more males and patients were younger than in the sporadic group.
  • Intra-abdominal desmoids were more common in the FAP group.
  • CONCLUSIONS: Patients with desmoid carry an elevated risk of FAP and therefore screening is indicated.
  • Asymptomatic patients with desmoid situated in extra truncal region may not need to be screened.
  • [MeSH-major] Adenomatous Polyposis Coli / diagnosis. Adenomatous Polyposis Coli / epidemiology. Endoscopy, Gastrointestinal. Fibromatosis, Aggressive / complications. Genes, APC. Mutation

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  • [Copyright] © 2015 Wiley Periodicals, Inc.
  • (PMID = 26663236.001).
  • [ISSN] 1096-9098
  • [Journal-full-title] Journal of surgical oncology
  • [ISO-abbreviation] J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Research Support, Non-U.S. Gov't
  • [Publication-country] United States
  • [Chemical-registry-number] Attenuated familial adenomatous polyposis
  • [Keywords] NOTNLM ; APC gene testing / desmoid tumor / familial adenomatous polyposis
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88. Hayashi K, Takamura M, Yokoyama H, Sato Y, Yamagiwa S, Nogami H, Wakai T, Hasegawa G, Terai S: A Mesenteric Desmoid Tumor with Rapid Progression. Intern Med; 2017;56(5):505-508
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  • [Title] A Mesenteric Desmoid Tumor with Rapid Progression.
  • We herein report the case of a rapidly progressive sporadic mesenteric desmoid tumor (DT).
  • [MeSH-major] Fibromatosis, Aggressive / diagnostic imaging. Mesentery. Peritoneal Neoplasms / diagnostic imaging
  • [MeSH-minor] Disease Progression. Female. Humans. Magnetic Resonance Imaging. Middle Aged. Tomography, X-Ray Computed

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  • (PMID = 28250295.001).
  • [ISSN] 1349-7235
  • [Journal-full-title] Internal medicine (Tokyo, Japan)
  • [ISO-abbreviation] Intern. Med.
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Japan
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89. Church J, Xhaja X, LaGuardia L, O'Malley M, Burke C, Kalady M: Desmoids and genotype in familial adenomatous polyposis. Dis Colon Rectum; 2015 Apr;58(4):444-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • BACKGROUND: Desmoid disease can be a serious, life-threatening complication of familial adenomatous polyposis.
  • The ability to predict patients at increased desmoid risk is important, but a convincing genotype-phenotype correlation for desmoid formation has not yet been described.
  • PURPOSE: The aim of this study is to assess the relationship between desmoid disease and genotype in patients with familial adenomatous polyposis.
  • MAIN OUTCOMES MEASURES: The comparison of genotype and the presence, stage, and site of desmoid disease are the primary end points of this study.
  • Desmoid disease was diagnosed in 77 patients from 68 families.
  • Desmoid disease was found in 14.9% of patients with a mutation 5' of codon 400, 23.2% of patients with a mutation from codon 401 to 1400, and in 37.1% of those with a mutation 3' of 1400.
  • All patients with 5' mutations had stage I or II abdominal desmoid disease, and all tumors were stable or shrinking.
  • Twelve percent of patients who had desmoid disease with mutations between codons 400 and 1400 had stage III or IV desmoid disease, and 5 of 42 (12%) tumors were growing at the time of the study.
  • There had been 2 desmoid-related deaths.
  • Almost half (44%) of patients who had desmoid disease with mutations 3' of codon 1400 had stage III or IV disease.
  • Three of 14 tumors were growing (21%), and there were 4 desmoid-related deaths.
  • CONCLUSION: Desmoid disease occurs in patients who have familial adenomatous polyposis with almost any APC mutation, although there is an increased propensity in those with a 3' mutation.
  • The incidence and severity of the desmoid disease are related to the site of the mutation.
  • [MeSH-major] Abdominal Neoplasms / genetics. Adenomatous Polyposis Coli / genetics. Fibromatosis, Aggressive / genetics. Genes, APC

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  • (PMID = 25751801.001).
  • [ISSN] 1530-0358
  • [Journal-full-title] Diseases of the colon and rectum
  • [ISO-abbreviation] Dis. Colon Rectum
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] Desmoid disease, hereditary
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90. Nagata T, Demizu Y, Okumura T, Sekine S, Hashimoto N, Fuwa N, Okimoto T, Shimada Y: Erratum to: Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report. World J Surg Oncol; 2017 05 03;15(1):95
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  • [Title] Erratum to: Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report.

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  • [ErratumFor] World J Surg Oncol. 2016 Sep 13;14 (1):245 [27624694.001]
  • [Cites] World J Surg Oncol. 2016 Sep 13;14 (1):245 [27624694.001]
  • (PMID = 28468632.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Journal Article; Published Erratum
  • [Publication-country] England
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91. Nagata T, Demizu Y, Okumura T, Sekine S, Hashimoto N, Fuwa N, Okimoto T, Shimada Y: Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report. World J Surg Oncol; 2016 Sep 13;14(1):245
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  • [Title] Carbon ion radiotherapy for desmoid tumor of the abdominal wall: a case report.
  • BACKGROUND: Desmoid tumors, which are associated with familial adenomatous polyposis (FAP), tend to occur frequently in the abdominal wall and mesentery.
  • CASE PRESENTATION: After surgery that was performed on a 39-year-old patient with FAP, we performed a second tumor excision which was the procedure used for frequently occurring mesenteric desmoid tumors.
  • It was determined that the enlarged tumor would be difficult to operate on through an abdominal incision.
  • Three years later, the tumor still remains reduced in size.
  • CONCLUSIONS: This is the first instance that the carbon ion radiotherapy has been effective for the unresected desmoid tumor, and it is believed that this will become the one effective option for the treatment of desmoid tumors.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Fibromatosis, Abdominal / radiotherapy. Fibromatosis, Aggressive / radiotherapy. Heavy Ion Radiotherapy. Neoplasm Recurrence, Local / radiotherapy. Peritoneal Neoplasms / radiotherapy
  • [MeSH-minor] Abdominal Wall / pathology. Colectomy / adverse effects. Duodenostomy. Humans. Ileostomy / adverse effects. Jejunostomy. Male. Mesentery / pathology. Middle Aged. Tissue Adhesions / complications. Tissue Adhesions / etiology. Tomography, X-Ray Computed

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  • [Cites] Ann Oncol. 2003 Feb;14(2):181-90 [12562642.001]
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  • [ErratumIn] World J Surg Oncol. 2017 May 3;15(1):95 [28468632.001]
  • (PMID = 27624694.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Carbon ion radiotherapy (major topic) / Desmoid tumor (major topic) / Mesenteric (major topic) / Unresectable (major topic)
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92. Miyata K, Fukaya M, Nagino M: Gradually shrinking intra-abdominal desmoid tumor derived from the stomach in a young boy: a case report. Surg Case Rep; 2017 Dec;3(1):54
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  • [Title] Gradually shrinking intra-abdominal desmoid tumor derived from the stomach in a young boy: a case report.
  • BACKGROUND: Intra-abdominal desmoid tumors, particularly those derived from the stomach, are rare.
  • In addition, spontaneous shrinking of an intra-abdominal desmoid tumor is rarer.
  • And desmoid tumors most commonly arise during the fourth decade of life.
  • CASE PRESENTATION: A 17-year-old boy with lower abdominal pain was diagnosed with a gastrointestinal stromal tumor (GIST) or a hematoma at a local hospital.
  • Abdominal computed tomography (CT) was performed for observational purposes three times over a 9-month period.
  • The tumor gradually decreased in size over time; however, the tumor did not shrink sufficiently to be diagnosed as a hematoma.
  • Operative findings revealed that the tumor was a hard mass firmly attached to both the greater curvature of the stomach and the inferior pole of the spleen.
  • Pathologically, the tumor was diagnosed as a desmoid tumor derived from the stomach.
  • CONCLUSION: For a young boy without a history of FAP, trauma, or surgical procedures, it is difficult to define an intra-abdominal tumor near the stomach as a desmoid tumor.
  • In such cases, surgical resection is recommended for a definitive diagnosis.

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  • (PMID = 28429313.001).
  • [ISSN] 2198-7793
  • [Journal-full-title] Surgical case reports
  • [ISO-abbreviation] Surg Case Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Germany
  • [Keywords] NOTNLM ; Desmoid tumor / Stomach / Young boy
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93. Kim DU, McQuinn G, Lin E, Lee M: Renographic Demonstration of Desmoid Tumor-Ureteral Fistula. Clin Nucl Med; 2016 Jan;41(1):44-5
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  • [Title] Renographic Demonstration of Desmoid Tumor-Ureteral Fistula.
  • A 20-year-old woman with Gardner syndrome and intra-abdominal desmoid tumors presented with increasing abdominal pain.
  • CT demonstrated a new area of central hypodensity in a presumed desmoid tumor, compressing the left ureter.
  • Subsequent 99mTc-MAG3 renogram demonstrated persistent extraureteral radiotracer activity in the region of the tumor, confirming a desmoid tumor-ureteral fistula.
  • Desmoid tumors are benign but locally aggressive fibrous neoplasms that can be sporadic or associated with familial adenomatous polyposis syndromes, specifically Gardner syndrome.
  • [MeSH-major] Fibromatosis, Aggressive / complications. Fibromatosis, Aggressive / radionuclide imaging. Radioisotope Renography. Ureteral Diseases / complications. Urinary Fistula / complications

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  • (PMID = 26284772.001).
  • [ISSN] 1536-0229
  • [Journal-full-title] Clinical nuclear medicine
  • [ISO-abbreviation] Clin Nucl Med
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] United States
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94. Yamamoto H, Arakaki K, Morimatsu K, Zaitsu Y, Fujita A, Kohashi K, Hirahashi M, Motoshita J, Oshiro Y, Oda Y: Insulin-like growth factor II messenger RNA-binding protein 3 expression in gastrointestinal mesenchymal tumors. Hum Pathol; 2014 Mar;45(3):481-7
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  • Insulin-like growth factor II messenger RNA-binding protein 3 (IMP3) is a recently identified biomarker demonstrated to be useful in diagnosis and prognostic prediction for several kinds of malignant tumors.
  • In this study, we examined the immunohistochemical expression of IMP3 in gastrointestinal stromal tumor (GIST) (n = 150), malignant melanoma (n = 17), malignant mesothelioma (n = 6), leiomyosarcoma (n = 6), inflammatory myofibroblastic tumor (IMT) (n = 12), desmoid fibromatosis (n = 8), leiomyoma (n = 20), and schwannoma (n = 20).
  • Other kinds of tumors, including GIST, desmoid fibromatosis, leiomyoma and schwannoma, were essentially negative for IMP3.
  • Our results suggest that IMP3 may be an ancillary tool in identifying aggressive abdominal mesenchymal tumors other than GIST.
  • [MeSH-major] Biomarkers, Tumor / metabolism. Gastrointestinal Neoplasms / diagnosis. Gastrointestinal Stromal Tumors / diagnosis. RNA-Binding Proteins / metabolism
  • [MeSH-minor] Diagnosis, Differential. Humans. Leiomyoma / diagnosis. Leiomyoma / metabolism. Leiomyoma / pathology. Leiomyosarcoma / diagnosis. Leiomyosarcoma / metabolism. Leiomyosarcoma / pathology. Lung Neoplasms / diagnosis. Lung Neoplasms / metabolism. Lung Neoplasms / pathology. Melanoma / diagnosis. Melanoma / metabolism. Melanoma / pathology. Mesothelioma / diagnosis. Mesothelioma / metabolism. Mesothelioma / pathology. Neurilemmoma / diagnosis. Neurilemmoma / metabolism. Neurilemmoma / pathology. Prognosis

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  • [Copyright] © 2014.
  • (PMID = 24411949.001).
  • [ISSN] 1532-8392
  • [Journal-full-title] Human pathology
  • [ISO-abbreviation] Hum. Pathol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Chemical-registry-number] 0 / Biomarkers, Tumor; 0 / IMP3 protein, human; 0 / RNA-Binding Proteins; Mesothelioma, Malignant
  • [Keywords] NOTNLM ; Differential diagnosis / Gastrointestinal stromal tumor / IMP3 / Immunohistochemistry / Inflammatory myofibroblastic tumor
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96. Li W, Zhou Y, Li Q, Tong H, Lu W: Intestinal perforation during chemotherapeutic treatment of intra-abdominal desmoid tumor in patients with Gardner's syndrome: report of two cases. World J Surg Oncol; 2016 Jul 04;14(1):178
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  • [Title] Intestinal perforation during chemotherapeutic treatment of intra-abdominal desmoid tumor in patients with Gardner's syndrome: report of two cases.
  • BACKGROUND: A minority of intra-abdominal desmoid tumors is associated with Gardner's syndrome in which desmoid tumors become an important cause of morbidity and mortality if they are surgically unresectable.
  • CASE PRESENTATION: Here, we report two cases of intestinal perforation during chemotherapy in patients with Gardner's syndrome-associated intra-abdominal desmoids.
  • Significant tumor regression was observed clinically.
  • CONCLUSIONS: The doxorubicin plus dacarbazine chemotherapy is an effective treatment for intra-abdominal demoid tumors in patients with Gardner's syndrome.
  • On the other hand, given severe adverse events might occur, clinicians should pay more attention that tumor quick regression may cause intestinal perforation in which urgent surgical intervention is necessary.
  • [MeSH-major] Abdominal Neoplasms / drug therapy. Antineoplastic Combined Chemotherapy Protocols / adverse effects. Fibromatosis, Aggressive / drug therapy. Gardner Syndrome / complications. Intestinal Perforation / chemically induced

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  • (PMID = 27377916.001).
  • [ISSN] 1477-7819
  • [Journal-full-title] World journal of surgical oncology
  • [ISO-abbreviation] World J Surg Oncol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] England
  • [Chemical-registry-number] 0 / Antineoplastic Agents; 0 / Thiazines; 0 / Thiazoles; 7GR28W0FJI / Dacarbazine; 80168379AG / Doxorubicin; VG2QF83CGL / meloxicam
  • [Other-IDs] NLM/ PMC4932702
  • [Keywords] NOTNLM ; Chemotherapy (major topic) / Desmoid tumors (major topic) / Gardner’s syndrome (major topic) / Intestinal perforation (major topic)
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97. Palacios-Zertuche JT, Cardona-Huerta S, Juárez-García ML, Valdés-Flores E, Muñoz-Maldonado GE: [Case report: Rapidly growing abdominal wall giant desmoid tumour during pregnancy]. Cir Cir; 2017 Jul - Aug;85(4):339-343
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  • [Title] [Case report: Rapidly growing abdominal wall giant desmoid tumour during pregnancy].
  • [Transliterated title] Reporte de caso: tumor desmoides gigante de pared abdominal con rápido crecimiento durante el embarazo.
  • BACKGROUND: Desmoid tumours are one of the rarest tumours worldwide, with an estimated yearly incidence of 2-4 new cases per million people.
  • It seems that the hormonal and immunological changes occurring during pregnancy may play a role in the severity and course of the disease.
  • CLINICAL CASE: The case is presented on 28-year-old female in her fifth week of gestation, in whom an abdominal wall tumour was found attached to left adnexa and uterus while performing a prenatal ultrasound.
  • Tumour biopsy was taken during the procedure.
  • Histopathology reported a desmoid fibromatosis.
  • A contrast enhanced abdominal computed tomography scan was performed, showing a tumour of 26×20.5×18cm, with well-defined borders in contact with the uterus, left adnexa, bladder and abdominal wall, with no evidence of infiltration to adjacent structures.
  • A laparotomy, with tumour resection, hysterectomy and left salpingo-oophorectomy, components separation techniques, polypropylene mesh insertion, and drainage was performed.
  • The final histopathology report was desmoid fibromatosis.
  • CONCLUSIONS: Desmoid tumours are locally aggressive and surgical resection with clear margins is the basis for the treatment of this disease, using radiotherapy, chemotherapy and hormone therapy as an adjunct in the treatment.

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  • [Copyright] Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.
  • (PMID = 27318390.001).
  • [ISSN] 0009-7411
  • [Journal-full-title] Cirugia y cirujanos
  • [ISO-abbreviation] Cir Cir
  • [Language] spa
  • [Publication-type] English Abstract; Journal Article
  • [Publication-country] Spain
  • [Keywords] NOTNLM ; Desmoid tumour / Embarazo / Pregnancy / Rapid growth / Rápido crecimiento / Tumor desmoide
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98. Oldani A, Garavoglia M: Hepatocellular cancer arising from ectopic liver tissue on diaphragm. Case report. Ann Ital Chir; 2014;85(ePub)
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  • MATERIAL OF STUDY: A 54 years old male patient was admitted to our Institution because of thoraco - abdominal pain (lower left chest, left hypochondrium), and fever; CEA and CA 19-9 were in range, but alpha fetoprotein levels were high (880 IU / L); CT scan and NMR showed a thoraco - abdominal mass developing from the left hemidiaphragm, with infiltration of the cranial part of the spleen; no primitive liver tumors have been detected.
  • RESULTS: The patient underwent surgical resection of the thoraco - abdominal tumor and of the mesenteric mass.
  • HISTOLOGY: hepatocellular carcinoma arising from ectopic islet of liver tissue on left hemidiaphragm; mesenteric desmoid tumor.
  • CONCLUSIONS: The case we have observed showed a coexistence of two very rare tumors; carcinogenesis on ectopic liver should be suspected in this patient with a thoraco-abdominal mass with high alpha fetoprotein levels, in absence of primitive liver chronic diseases and cancer.

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  • (PMID = 24845155.001).
  • [ISSN] 2239-253X
  • [Journal-full-title] Annali italiani di chirurgia
  • [ISO-abbreviation] Ann Ital Chir
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article
  • [Publication-country] Italy
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99. Zhou H, Lu H, Wang L, Xie L, Wu M, Li J, Abdallahi N, Lin Z: Abdominal wall desmoid tumor during pregnancy: case report and literature review. Clin Exp Obstet Gynecol; 2015;42(2):253-8
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Abdominal wall desmoid tumor during pregnancy: case report and literature review.
  • Desmoid tumors are fibromatous lesions that are the result of abnormal proliferation of myofibroblasts.
  • Despite its benign microscopic appearance and non-metastasizing behavior, tumor infiltrates surrounding tissues and has a high risk of recurrence.
  • Pregnancy-associated desmoid tumors are very rare and optimal management of this tumor is not well established.
  • The authors report a case of a 31-year-old pregnant woman with a large desmoid tumor, which increased rapidly in size and caused worsening symptom of dyspnea.
  • The tumor was successfully removed during a caesarian section, which resulted in an anterior abdominal wall defect.
  • Reconstruction of the abdominal wall defect was performed with a polypropylene mesh.
  • The authors also reviewed the literature on the world's experience with this tumor and its management during pregnancy.Twelve desmoid tumors arising during pregnancy were reported in the existing literature; the managements were varied and has yet to be defined.
  • [MeSH-major] Abdominal Neoplasms / surgery. Abdominal Wall / surgery. Fibroma / surgery. Pregnancy Complications, Neoplastic / surgery
  • [MeSH-minor] Adult. Cesarean Section. Diagnosis, Differential. Female. Fibromatosis, Aggressive. Humans. Postoperative Period. Pregnancy. Reconstructive Surgical Procedures. Uterine Neoplasms / diagnosis

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  • (PMID = 26054134.001).
  • [ISSN] 0390-6663
  • [Journal-full-title] Clinical and experimental obstetrics & gynecology
  • [ISO-abbreviation] Clin Exp Obstet Gynecol
  • [Language] eng
  • [Publication-type] Case Reports; Journal Article; Review
  • [Publication-country] Canada
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100. Ueno H, Kobayashi H, Konishi T, Ishida F, Yamaguchi T, Hinoi T, Kanemitsu Y, Inoue Y, Tomita N, Matsubara N, Komori K, Ozawa H, Nagasaka T, Hasegawa H, Koyama M, Akagi Y, Yatsuoka T, Kumamoto K, Kurachi K, Tanakaya K, Yoshimatsu K, Watanabe T, Sugihara K, Ishida H: Prevalence of laparoscopic surgical treatment and its clinical outcomes in patients with familial adenomatous polyposis in Japan. Int J Clin Oncol; 2016 Aug;21(4):713-722
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  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • METHODS: This was a multicenter retrospective cohort study comprising 23 specialist institutions for colorectal disease and a cohort of 282 FAP patients who underwent total colectomy or proctocolectomy during 2000-2012.
  • No postoperative mortality was observed in this series, and laparoscopic surgery was comparable to open surgery in terms of stoma closure rate, incidence of intra-abdominal/abdominal desmoid tumors, and postoperative survival rate in both study periods.
  • [MeSH-major] Adenomatous Polyposis Coli / surgery. Colectomy / methods. Colorectal Neoplasms / surgery. Fibromatosis, Aggressive / surgery. Laparoscopy

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  • (PMID = 26820718.001).
  • [ISSN] 1437-7772
  • [Journal-full-title] International journal of clinical oncology
  • [ISO-abbreviation] Int. J. Clin. Oncol.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] Japan
  • [Keywords] NOTNLM ; Desmoid tumor / Familial adenomatous polyposis (FAP) / Laparoscopic surgery / Total colectomy / Total proctocolectomy
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